Detailed information of TA system    

insolicoBioinformatically predicted

Overview


TA module


Type VIII Classification (family/domain) SdsR-RyeA/-
Location 1917343..1917488 Replicon chromosome
Accession NZ_CP031792
Organism Klebsiella pneumoniae strain INF116-sc-2279924

Toxin (RNA)


Gene name SdsR
Locus tag -
Coordinates 1917379..1917481 (+)

Antitoxin (RNA)


Gene name RyeA
Locus tag -
Coordinates 1917343..1917488 (-)

Genomic Context


Locus tag Coordinates Strand Size (bp) Protein ID Product Description
D0883_RS09480 1912473..1914533 + 2061 WP_004151449.1 oligopeptidase B -
D0883_RS09485 1914537..1915196 - 660 WP_002911407.1 exodeoxyribonuclease X -
D0883_RS09490 1915275..1915505 - 231 WP_002911406.1 DNA polymerase III subunit theta -
D0883_RS09495 1915618..1915992 + 375 WP_004151448.1 CopC domain-containing protein YobA -
D0883_RS09500 1915996..1916865 + 870 WP_004175431.1 copper homeostasis membrane protein CopD -
D0883_RS09505 1916882..1917220 + 339 WP_002911404.1 YebY family protein -
- 1917343..1917488 - 146 - - Antitoxin
- 1917379..1917481 + 103 - - Toxin
D0883_RS27655 1917856..1917999 - 144 WP_002911398.1 Ecr family regulatory small membrane protein -
D0883_RS09515 1918104..1919072 - 969 WP_014907334.1 VirK/YbjX family protein -
D0883_RS09520 1919229..1919882 + 654 WP_020804905.1 protein-serine/threonine phosphatase -
D0883_RS09525 1919879..1920070 - 192 WP_002911395.1 YebW family protein -
D0883_RS09530 1920168..1920407 - 240 WP_002911393.1 YebV family protein -
D0883_RS09535 1920523..1921956 - 1434 WP_004148845.1 16S rRNA (cytosine(1407)-C(5))-methyltransferase RsmF -

Associated MGEs


MGE
detail
Similar
MGEs
Relative
position
MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Sequences


Toxin        


Download         Length: 103 bp

>T110105 NZ_CP031792:1917379-1917481 [Klebsiella pneumoniae]
GCAAGGCGACTTAGCCTGCATTAATGCCAACTTTTAGCGCACGGCTCTCTCCCAAGAGCCATTTCCCTGGACCGAATACA
GGAATCGTATTCGGTCTCTTTTT

Antitoxin


Download         Length: 146 bp

>AT110105 NZ_CP031792:c1917488-1917343 [Klebsiella pneumoniae]
TAAAGATAAAAAGAGACCGAATACGATTCCTGTATTCGGTCCAGGGAAATGGCTCTTGGGAGAGAGCCGTGCGCTAAAAG
TTGGCATTAATGCAGGCTAAGTCGCCTTGCACTATAAGAATAGTTTAACGCGTCAGCTTTTCCAGT

Structures


Antitoxin

Download structure file

Antitoxin

Download structure file

References