Detailed information of TA system TA110027

Bioinformatically predicted

Overview

TA module

• Type: II
• Classification (family/domain): ataRT/DUF1778(antitoxin)
• Location: 4308403..4309172
• Replicon: chromosome
• Accession: NZ_CP031775
• Organism: Shewanella decolorationis strain Ni1-3

Toxin (Protein)

• Gene name: ataT
• Uniprot ID: -
• Locus tag: D0436_RS18780
• Protein ID: WP_096070663.1
• Coordinates: 4308660..4309172 (+)
• Length: 171 a.a.

Antitoxin (Protein)

• Gene name: ataR
• Uniprot ID: -
• Locus tag: D0436_RS18775
• Protein ID: WP_000212004.1
• Coordinates: 4308403..4308669 (+)
• Length: 89 a.a.

Genomic Context

Locus tag	Coordinates	Strand	Size (bp)	Protein ID	Product	Description
D0436_RS18755 (D0436_04045)	4304104..4304616	-	513	WP_175542028.1	S26 family signal peptidase	-
D0436_RS18760 (D0436_04040)	4304600..4304947	-	348	WP_071701358.1	plasmid-related protein	-
D0436_RS18765 (D0436_04035)	4304940..4307342	-	2403	WP_208661501.1	type IV secretion system protein TraC	-
D0436_RS18770 (D0436_04030)	4307342..4308034	-	693	WP_096070662.1	DsbC family protein	-
D0436_RS18775 (D0436_04025)	4308403..4308669	+	267	WP_000212004.1	DUF1778 domain-containing protein	Antitoxin
D0436_RS18780 (D0436_04020)	4308660..4309172	+	513	WP_096070663.1	GNAT family N-acetyltransferase	Toxin
D0436_RS18785 (D0436_04015)	4309208..4309594	-	387	WP_000180225.1	TraA family conjugative transfer protein	-
D0436_RS18790 (D0436_04010)	4309591..4310163	-	573	WP_024008834.1	type IV conjugative transfer system lipoprotein TraV	-
D0436_RS18795 (D0436_04005)	4310238..4311527	-	1290	WP_208661500.1	TraB/VirB10 family protein	-
D0436_RS18800 (D0436_04000)	4311530..4312426	-	897	WP_208662888.1	type-F conjugative transfer system secretin TraK	-
D0436_RS18805 (D0436_03995)	4312410..4313036	-	627	WP_208661498.1	TraE/TraK family type IV conjugative transfer system protein	-
D0436_RS18810 (D0436_03990)	4313033..4313314	-	282	WP_000433891.1	type IV conjugative transfer system protein TraL	-

Associated MGEs

MGE detail	Similar MGEs	Relative position	MGE Type	Cargo ARG	Virulence gene	Coordinates	Length (bp)

Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.

Domains

Predicted by InterproScan

Toxin

• GNAT domain (42-146)

Antitoxin

• Vibrio phage ICP1, Orf50 (8-83)

Sequences

Toxin

Protein

• Length: 171 a.a.
• Molecular weight: 18719.63 Da
• Isoelectric Point: 8.7083

>T110027 WP_096070663.1 NZ_CP031775:4308660-4309172 [Shewanella decolorationis]
MGISAPTLLTDEHQLNAFQCGIEELDTWLRKQALKNQKRGTARVYVVNDTEVHQVIGYYAIAMGSVSREQAFSSLRRNSP
DPIPMVILARLGVDKAHQGQGIAAGLLKDCIIRSVQAMNAVGGAGILVHAIDDTAQTFYKKFGFKESTFDPLVLMARICD
IEKSLSTRLR

Nucleotide

• Length: 513 bp

>T110027 NZ_CP031775:4308660-4309172 [Shewanella decolorationis]
TTGGGAATAAGTGCACCAACCCTCCTCACTGATGAGCACCAGCTTAATGCCTTTCAATGTGGCATCGAAGAACTCGATAC
TTGGTTAAGAAAGCAGGCGTTAAAGAATCAAAAGCGGGGAACCGCGAGAGTGTATGTGGTCAATGACACGGAAGTACATC
AAGTGATTGGGTACTATGCCATTGCCATGGGATCAGTTTCCAGAGAGCAAGCCTTCAGTTCATTAAGAAGAAATAGTCCA
GATCCCATTCCCATGGTGATTCTAGCCAGGCTTGGAGTAGATAAAGCCCATCAAGGTCAAGGCATTGCAGCCGGTCTTTT
AAAAGATTGTATCATTCGCTCAGTACAAGCAATGAACGCTGTCGGTGGAGCAGGAATTTTAGTTCATGCTATTGATGACA
CTGCGCAAACGTTCTACAAGAAATTTGGCTTCAAAGAATCGACGTTTGATCCTTTAGTACTCATGGCAAGGATCTGCGAT
ATCGAAAAATCATTGTCGACAAGACTGAGATGA

Antitoxin

Protein

• Length: 89 a.a.
• Molecular weight: 9956.48 Da
• Isoelectric Point: 5.8580

>AT110027 WP_000212004.1 NZ_CP031775:4308403-4308669 [Shewanella decolorationis]
MATKTAPINMRVLPSVRDIIDAAASLKKVDRTVFIQQAALNEAHSILAEQRDFVLEAKAFEAFDNELRAEPQTLEGMKDL
FKRKAPWE

Nucleotide

• Length: 267 bp

>AT110027 NZ_CP031775:4308403-4308669 [Shewanella decolorationis]
ATGGCTACAAAGACAGCCCCAATCAACATGCGAGTACTGCCATCGGTAAGAGACATCATCGATGCCGCAGCAAGTTTAAA
AAAAGTTGATAGAACCGTGTTCATTCAGCAAGCAGCGCTCAATGAAGCGCATAGTATACTGGCAGAACAGCGGGATTTTG
TTCTAGAAGCAAAGGCTTTTGAAGCGTTTGATAACGAACTTCGTGCAGAGCCACAGACTCTTGAAGGTATGAAAGATCTG
TTTAAGAGGAAAGCGCCTTGGGAATAA