Detailed information of TA system TA110025

Bioinformatically predicted

Overview

TA module

• Type: IV
• Classification (family/domain): ygfYX/Cpta(toxin)
• Location: 1467953..1468622
• Replicon: chromosome
• Accession: NZ_CP031775
• Organism: Shewanella decolorationis strain Ni1-3

Toxin (Protein)

• Gene name: ygfX
• Uniprot ID: -
• Locus tag: D0436_RS23385
• Protein ID: WP_254803617.1
• Coordinates: 1468182..1468622 (+)
• Length: 147 a.a.

Antitoxin (Protein)

• Gene name: ygfY
• Uniprot ID: -
• Locus tag: D0436_RS06395
• Protein ID: WP_084294861.1
• Coordinates: 1467953..1468201 (+)
• Length: 83 a.a.

Genomic Context

Locus tag	Coordinates	Strand	Size (bp)	Protein ID	Product	Description
D0436_RS06370 (D0436_16110)	1463590..1464396	+	807	WP_011717885.1	prolipoprotein diacylglyceryl transferase	-
D0436_RS06375 (D0436_16105)	1464396..1465190	+	795	WP_208659651.1	thymidylate synthase	-
D0436_RS06380 (D0436_16100)	1465308..1466477	+	1170	WP_126511708.1	Na+/H+ antiporter NhaA	-
D0436_RS06385 (D0436_16095)	1466480..1466866	+	387	WP_023266792.1	hypothetical protein	-
D0436_RS06390 (D0436_16090)	1466962..1467870	+	909	WP_023266793.1	transcriptional activator NhaR	-
D0436_RS06395 (D0436_16085)	1467953..1468201	+	249	WP_084294861.1	succinate dehydrogenase assembly factor 2	Antitoxin
D0436_RS23385	1468182..1468622	+	441	WP_254803617.1	hypothetical protein	Toxin
D0436_RS06400 (D0436_16075)	1468713..1470326	-	1614	WP_086903302.1	L-aspartate oxidase	-
D0436_RS06405 (D0436_16070)	1470516..1471094	+	579	WP_011623604.1	RNA polymerase sigma factor RpoE	-
D0436_RS06410 (D0436_16065)	1471121..1471744	+	624	WP_208659650.1	RseA family anti-sigma factor	-
D0436_RS06415 (D0436_16060)	1471757..1472689	+	933	WP_208659649.1	MucB/RseB C-terminal domain-containing protein	-
D0436_RS06420 (D0436_16055)	1472701..1473174	+	474	WP_208659648.1	SoxR reducing system RseC family protein	-

Associated MGEs

MGE detail	Similar MGEs	Relative position	MGE Type	Cargo ARG	Virulence gene	Coordinates	Length (bp)

Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.

Domains

Predicted by InterproScan

Toxin

• Inner membrane protein YgfX (5-134)

Antitoxin

• Flavinator of succinate dehydrogenase (7-77)

Sequences

Toxin

Protein

• Length: 147 a.a.
• Molecular weight: 17093.11 Da
• Isoelectric Point: 8.9094

>T110025 WP_254803617.1 NZ_CP031775:1468182-1468622 [Shewanella decolorationis]
VAERRHSFSVKASRDQRLSLVVFVCVCGTSLLIWPETDVVFWLVLKLVFAVLILGFLGYKLWRLRTWHCRFELNGKGEGW
LSTGEAFYVLPRTWVTPFVCLIYYQSADKLYLLPLWADMFSDTDYRHLCRLLLKVKTQATSQHESL

Nucleotide

• Length: 441 bp

>T110025 NZ_CP031775:1468182-1468622 [Shewanella decolorationis]
GTGGCAGAGCGGCGCCATAGTTTTAGCGTAAAAGCCTCTCGCGACCAGCGACTCTCGTTGGTCGTTTTTGTTTGTGTCTG
CGGTACCTCGTTACTTATCTGGCCTGAAACGGACGTCGTATTTTGGCTTGTGCTTAAGTTAGTGTTCGCTGTTTTAATCC
TCGGATTCTTGGGCTATAAGTTATGGCGACTGAGAACTTGGCATTGTCGTTTTGAGCTCAATGGAAAGGGGGAAGGCTGG
CTCTCGACGGGGGAGGCGTTTTATGTACTCCCGAGAACTTGGGTAACGCCCTTTGTTTGCTTAATTTACTATCAGTCTGC
CGATAAGTTGTATCTCTTGCCCCTTTGGGCCGATATGTTTAGCGATACAGATTACCGCCACTTATGCCGGCTATTACTTA
AAGTTAAAACTCAGGCGACGAGCCAACATGAGTCCTTGTAA

Antitoxin

Protein

• Length: 83 a.a.
• Molecular weight: 9559.09 Da
• Isoelectric Point: 4.3313

>AT110025 WP_084294861.1 NZ_CP031775:1467953-1468201 [Shewanella decolorationis]
MELMNIARVRWACRRGMLELDVLFQPFVENVYQDLSDDDKALFIRLLECEDPELFAWFMGHEACPDAELARMVVQVRGRA
AP

Nucleotide

• Length: 249 bp

>AT110025 NZ_CP031775:1467953-1468201 [Shewanella decolorationis]
TTGGAGTTAATGAACATTGCACGGGTCCGCTGGGCATGTCGCCGCGGAATGCTCGAATTGGACGTCTTGTTCCAGCCTTT
CGTCGAAAATGTTTATCAGGATTTGTCGGATGACGACAAGGCCCTGTTTATTCGTTTACTCGAGTGTGAAGACCCTGAAT
TATTTGCTTGGTTTATGGGTCATGAAGCCTGTCCCGATGCAGAGCTTGCCCGCATGGTAGTGCAAGTCCGTGGCAGAGCG
GCGCCATAG