Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type II Classification (family/domain) parDE/ParE-CC2985
Location 261649..262195 Replicon plasmid p.A
Accession NZ_CP031752
Organism Cereibacter sphaeroides strain EBL0706

Toxin (Protein)


Gene name parE Uniprot ID -
Locus tag D0Z66_RS20735 Protein ID WP_011910870.1
Coordinates 261649..261942 (-) Length 98 a.a.

Antitoxin (Protein)


Gene name parD Uniprot ID -
Locus tag D0Z66_RS20740 Protein ID WP_011910869.1
Coordinates 261929..262195 (-) Length 89 a.a.

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
D0Z66_RS22275 256860..257003 - 144 WP_181969655.1 hypothetical protein -
D0Z66_RS20715 257218..258420 + 1203 WP_117345263.1 Fic family protein -
D0Z66_RS20720 258514..259746 - 1233 WP_181969656.1 AAA family ATPase -
D0Z66_RS20725 260352..260771 + 420 WP_011910872.1 hypothetical protein -
D0Z66_RS20730 261316..261564 - 249 WP_011910871.1 AzlD domain-containing protein -
D0Z66_RS20735 261649..261942 - 294 WP_011910870.1 type II toxin-antitoxin system RelE/ParE family toxin Toxin
D0Z66_RS20740 261929..262195 - 267 WP_011910869.1 type II toxin-antitoxin system ParD family antitoxin Antitoxin
D0Z66_RS20750 262871..263695 + 825 Protein_249 hypothetical protein -
D0Z66_RS20760 264713..266044 - 1332 WP_011910866.1 HipA domain-containing protein -
D0Z66_RS20765 266044..266355 - 312 WP_080517499.1 helix-turn-helix transcriptional regulator -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)
- inside Non-Mobilizable plasmid - - 1..298364 298364


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin

Toxin-antitoxin system, RelE/ParE toxin family

(4-92)

Antitoxin

Antitoxin ParD

(2-80)


Sequences

Toxin        


Download         Length: 98 a.a.        Molecular weight: 11036.64 Da        Isoelectric Point: 7.4636

>T109992 WP_011910870.1 NZ_CP031752:c261942-261649 [Cereibacter sphaeroides]
VTKIDFTRDAERDLIDIFLYGIEHFGPVQAERYTKTLNAKIDMAAEHPDFGADYGFVIKGVRRYEAVSHAIYYRSTGVGI
LVLRVLHGRMDPARHLA

Download         Length: 294 bp

>T109992 NZ_CP031752:c261942-261649 [Cereibacter sphaeroides]
GTGACGAAAATTGACTTCACGCGTGATGCCGAACGGGACCTGATCGACATCTTCCTCTACGGGATCGAACATTTCGGCCC
GGTTCAGGCCGAGAGGTACACGAAGACGCTCAACGCCAAGATCGACATGGCGGCAGAGCATCCAGATTTTGGGGCTGACT
ACGGCTTCGTTATCAAGGGTGTTCGCAGGTACGAGGCTGTGTCCCACGCTATATACTACCGCTCTACAGGGGTAGGTATT
CTCGTGCTGCGCGTCCTGCACGGCCGGATGGATCCGGCCCGTCATCTGGCTTGA

Antitoxin


Download         Length: 89 a.a.        Molecular weight: 10073.22 Da        Isoelectric Point: 4.7064

>AT109992 WP_011910869.1 NZ_CP031752:c262195-261929 [Cereibacter sphaeroides]
MSRLTISMPDQMNEWVEAQIAAGRYGNVSEYFRDLVRRDQERREAAVAELRTMLERADASGVSDRSFPDILEAARREARQ
KGLLGDEN

Download         Length: 267 bp

>AT109992 NZ_CP031752:c262195-261929 [Cereibacter sphaeroides]
ATGTCCAGACTGACCATCTCGATGCCCGACCAGATGAACGAGTGGGTCGAGGCGCAGATCGCGGCGGGCCGTTACGGTAA
CGTCAGCGAGTACTTCCGGGACCTGGTACGGCGTGACCAAGAGCGCAGGGAAGCGGCCGTTGCCGAGCTCCGGACCATGC
TTGAGCGCGCGGACGCGAGCGGTGTCTCTGATCGCTCCTTCCCAGATATCCTGGAGGCGGCGCGCCGGGAGGCCCGACAA
AAGGGTCTGCTTGGTGACGAAAATTGA

Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure

Antitoxin

Source ID Structure

References