Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type II Classification (family/domain) vapBC/VapC-StbC
Location 161332..161987 Replicon chromosome
Accession NZ_CP031746
Organism Auritidibacter sp. NML130574

Toxin (Protein)


Gene name vapC Uniprot ID -
Locus tag DCC27_RS00835 Protein ID WP_110100194.1
Coordinates 161562..161987 (+) Length 142 a.a.

Antitoxin (Protein)


Gene name vapB Uniprot ID -
Locus tag DCC27_RS00830 Protein ID WP_110100006.1
Coordinates 161332..161565 (+) Length 78 a.a.

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
DCC27_RS00820 157597..159804 - 2208 WP_110100192.1 choline BCCT transporter BetT -
DCC27_RS00825 160099..161184 + 1086 WP_110100193.1 redox-regulated ATPase YchF -
DCC27_RS00830 161332..161565 + 234 WP_110100006.1 Arc family DNA-binding protein Antitoxin
DCC27_RS00835 161562..161987 + 426 WP_110100194.1 type II toxin-antitoxin system VapC family toxin Toxin
DCC27_RS00840 162000..162536 + 537 WP_158524689.1 GNAT family N-acetyltransferase -
DCC27_RS00845 162682..162876 - 195 WP_146206388.1 hypothetical protein -
DCC27_RS00850 163080..163805 + 726 WP_110100197.1 hypothetical protein -
DCC27_RS12275 164036..164263 + 228 WP_199445857.1 type II toxin-antitoxin system RelE/ParE family toxin -
DCC27_RS00860 164269..164574 + 306 WP_110100392.1 helix-turn-helix domain-containing protein -
DCC27_RS00865 164725..164958 + 234 WP_110100198.1 hypothetical protein -
DCC27_RS00870 164943..165317 + 375 WP_146206389.1 hypothetical protein -
DCC27_RS00875 165583..166347 + 765 WP_110100200.1 sulfite exporter TauE/SafE family protein -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin

PIN domain

(2-128)

Antitoxin

Arc-like DNA binding domain

(13-40)


Sequences

Toxin        


Download         Length: 142 a.a.        Molecular weight: 15255.42 Da        Isoelectric Point: 5.2123

>T109989 WP_110100194.1 NZ_CP031746:161562-161987 [Auritidibacter sp. NML130574]
VIILDTNVISEIFRPLPEPRVADWLTSLEGDVAITSVTLAELLAGLRRLPDGRRRDALTRRIDVALAPYRGGRAVLPFDD
VAADRYADVLVARERAGAPISTADAQTAAICLAHGATCATRNVKDFQHTGVELVDPWKVDA

Download         Length: 426 bp

>T109989 NZ_CP031746:161562-161987 [Auritidibacter sp. NML130574]
GTGATCATCCTCGACACAAACGTGATCTCGGAGATCTTTCGACCCTTGCCCGAGCCACGCGTAGCGGACTGGCTCACGTC
CCTGGAGGGTGACGTAGCCATCACGTCCGTCACGCTCGCAGAACTGCTGGCAGGTTTGCGGCGGTTGCCGGATGGTCGGC
GCAGAGATGCGCTGACCAGACGAATTGACGTGGCGCTCGCACCGTACAGGGGCGGCCGCGCTGTGTTGCCGTTCGATGAC
GTGGCCGCCGACCGCTATGCCGACGTGCTCGTGGCTCGAGAGCGCGCGGGAGCGCCGATCAGTACCGCCGACGCGCAGAC
CGCCGCGATCTGCCTGGCGCACGGAGCAACCTGCGCTACGCGCAATGTGAAGGACTTCCAGCACACCGGCGTAGAACTGG
TGGATCCGTGGAAGGTCGATGCGTGA

Antitoxin


Download         Length: 78 a.a.        Molecular weight: 8242.47 Da        Isoelectric Point: 5.6643

>AT109989 WP_110100006.1 NZ_CP031746:161332-161565 [Auritidibacter sp. NML130574]
MSSIIVRGLDDAVKQQLAAQAKEHGRSMEAEVRAILTKAARRPHIGIALLAAAQDVGGVEELPIPVRDDVARAVDFE

Download         Length: 234 bp

>AT109989 NZ_CP031746:161332-161565 [Auritidibacter sp. NML130574]
ATGTCATCCATCATCGTTCGCGGTCTCGACGACGCCGTGAAGCAGCAACTCGCTGCACAGGCGAAGGAGCACGGTCGGTC
GATGGAAGCCGAAGTTCGCGCCATCCTGACCAAAGCTGCACGCCGGCCGCACATAGGAATCGCTCTGCTGGCAGCCGCGC
AGGATGTCGGGGGAGTCGAGGAGCTACCGATCCCGGTGCGCGATGACGTCGCGCGGGCGGTGGACTTCGAGTGA

Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure

Antitoxin

Source ID Structure

References