Detailed information of TA system TA109985

Bioinformatically predicted

Overview

TA module

• Type: II
• Classification (family/domain): relBE/ParE-Phd
• Location: 4760208..4760761
• Replicon: chromosome
• Accession: NZ_CP031728
• Organism: Cellvibrio sp. KY-GH-1

Toxin (Protein)

• Gene name: relE
• Uniprot ID: -
• Locus tag: D0C16_RS20120
• Protein ID: WP_151033996.1
• Coordinates: 4760208..4760516 (-)
• Length: 103 a.a.

Antitoxin (Protein)

• Gene name: relB
• Uniprot ID: -
• Locus tag: D0C16_RS20125
• Protein ID: WP_151033997.1
• Coordinates: 4760504..4760761 (-)
• Length: 86 a.a.

Genomic Context

Locus tag	Coordinates	Strand	Size (bp)	Protein ID	Product	Description
D0C16_RS20100	4755313..4758645	-	3333	WP_191968564.1	ligand-binding sensor domain-containing diguanylate cyclase	-
D0C16_RS20105	4758788..4759003	-	216	WP_151033993.1	DUF4287 domain-containing protein	-
D0C16_RS20110	4759095..4759568	-	474	WP_151033994.1	L,D-transpeptidase family protein	-
D0C16_RS20115	4759565..4760167	-	603	WP_151033995.1	GNAT family N-acetyltransferase	-
D0C16_RS20120	4760208..4760516	-	309	WP_151033996.1	type II toxin-antitoxin system RelE/ParE family toxin	Toxin
D0C16_RS20125	4760504..4760761	-	258	WP_151033997.1	type II toxin-antitoxin system Phd/YefM family antitoxin	Antitoxin
D0C16_RS20130	4761437..4762009	-	573	WP_151033998.1	hypothetical protein	-
D0C16_RS20135	4762314..4763768	-	1455	WP_151033999.1	decarboxylating NADP(+)-dependent phosphogluconate dehydrogenase	-
D0C16_RS20140	4764028..4765146	-	1119	WP_151034000.1	tRNA epoxyqueuosine(34) reductase QueG	-

Associated MGEs

MGE detail	Similar MGEs	Relative position	MGE Type	Cargo ARG	Virulence gene	Coordinates	Length (bp)

Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.

Domains

Predicted by InterproScan

Toxin

• Toxin-antitoxin system, RelE/ParE toxin family (4-90)

Antitoxin

• Type II toxin-antitoxin system, antitoxin Phd/YefM (1-68)

Sequences

Toxin

Protein

• Length: 103 a.a.
• Molecular weight: 11659.55 Da
• Isoelectric Point: 6.7116

>T109985 WP_151033996.1 NZ_CP031728:c4760516-4760208 [Cellvibrio sp. KY-GH-1]
MVEIIWTNAATHDLNEIAEYIALSNPIAAAELVTDILAKVERLEQFPKSGKVPLAIPELNYRELTASPCRVLYRTDKNTV
HIMHVCREERSLRKFLIERGTL

Nucleotide

• Length: 309 bp

>T109985 NZ_CP031728:c4760516-4760208 [Cellvibrio sp. KY-GH-1]
ATGGTTGAAATAATATGGACCAACGCCGCAACTCACGACCTCAATGAAATCGCGGAATACATCGCCCTAAGCAACCCCAT
TGCAGCCGCAGAACTGGTAACGGATATTCTTGCTAAAGTTGAACGCCTTGAACAATTCCCCAAGTCGGGGAAGGTTCCTT
TAGCCATTCCTGAGCTAAATTATCGAGAACTAACTGCATCCCCTTGTCGGGTACTTTACCGCACAGACAAAAACACCGTT
CATATTATGCATGTGTGTCGCGAGGAGCGCAGCTTGCGAAAATTTCTAATAGAGCGGGGAACACTGTAA

Antitoxin

Protein

• Length: 86 a.a.
• Molecular weight: 9789.47 Da
• Isoelectric Point: 6.7289

>AT109985 WP_151033997.1 NZ_CP031728:c4760761-4760504 [Cellvibrio sp. KY-GH-1]
MKTELVTTLKREATKILAELHDTKEPVLITEHGLPSAYLVDVEDYEFMVDRMKLLEGIARGEKDILEGRVLTHAQAKDKL
KKWLK

Nucleotide

• Length: 258 bp

>AT109985 NZ_CP031728:c4760761-4760504 [Cellvibrio sp. KY-GH-1]
ATGAAAACCGAGCTTGTCACCACCCTGAAGCGTGAAGCCACCAAAATTTTGGCCGAGCTGCACGACACTAAAGAACCCGT
GCTTATCACCGAACACGGTTTACCTTCAGCTTATCTAGTAGATGTTGAAGACTATGAGTTTATGGTTGACCGGATGAAGC
TATTAGAAGGAATAGCACGAGGCGAAAAAGATATTTTAGAAGGACGAGTATTAACGCACGCACAAGCTAAGGATAAGCTG
AAGAAATGGTTGAAATAA