Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type II Classification (family/domain) /Xre(antitoxin)
Location 3930700..3931872 Replicon chromosome
Accession NZ_CP031728
Organism Cellvibrio sp. KY-GH-1

Toxin (Protein)


Gene name - Uniprot ID -
Locus tag D0C16_RS16640 Protein ID WP_151033393.1
Coordinates 3931123..3931872 (+) Length 250 a.a.

Antitoxin (Protein)


Gene name - Uniprot ID -
Locus tag D0C16_RS16635 Protein ID WP_151033392.1
Coordinates 3930700..3931071 (+) Length 124 a.a.

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
D0C16_RS16610 3926377..3926841 + 465 WP_151034974.1 Lrp/AsnC family transcriptional regulator -
D0C16_RS16615 3926916..3927962 - 1047 WP_151033388.1 TIGR00266 family protein -
D0C16_RS16620 3927974..3928657 - 684 WP_151033389.1 TIGR00266 family protein -
D0C16_RS16625 3928668..3929330 - 663 WP_151033390.1 TIGR00266 family protein -
D0C16_RS16630 3929320..3930513 - 1194 WP_151033391.1 M48 family metallopeptidase -
D0C16_RS16635 3930700..3931071 + 372 WP_151033392.1 XRE family transcriptional regulator Antitoxin
D0C16_RS16640 3931123..3931872 + 750 WP_151033393.1 RES family NAD+ phosphorylase Toxin
D0C16_RS16645 3931957..3932538 + 582 WP_151033394.1 TetR/AcrR family transcriptional regulator -
D0C16_RS16650 3932638..3933387 + 750 WP_151033395.1 SDR family NAD(P)-dependent oxidoreductase -
D0C16_RS16655 3933440..3934735 - 1296 WP_151033396.1 fibronectin type III domain-containing protein -
D0C16_RS16660 3934836..3935276 - 441 WP_151034975.1 cyanase -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin

RES domain

(61-205)

Antitoxin

Cro/C1-type helix-turn-helix domain

(25-73)


Sequences

Toxin        


Download         Length: 250 a.a.        Molecular weight: 27941.71 Da        Isoelectric Point: 6.6031

>T109983 WP_151033393.1 NZ_CP031728:3931123-3931872 [Cellvibrio sp. KY-GH-1]
MIWEACEGATQLQTISGTAWRLVESQEQIATLGYVDTLEEQALLEELLDSVKPPYPANSDGYHYLLKTPFRYPPLRWGSR
FGRIHEPGIFYAGGNAHTTLAESAFYRFVFWYSMAASPIKNTITSAHTLFSVNYASQRGVKLQVAPFDRFAQQLTDRKDY
SATQQLGSNMRAANVEVFEYQSARDPQRGHCVGLFVPAALSQKKPADMTQWLCELGASEVAFKQVGHKEIIHFPVDLFLV
DGRLPMPAA

Download         Length: 750 bp

>T109983 NZ_CP031728:3931123-3931872 [Cellvibrio sp. KY-GH-1]
ATGATCTGGGAAGCTTGCGAAGGAGCAACGCAGTTACAAACAATTTCTGGCACTGCCTGGCGGTTGGTAGAAAGTCAGGA
GCAAATCGCCACCCTGGGTTATGTGGATACCCTGGAAGAACAAGCACTATTGGAGGAGTTACTGGATTCGGTAAAACCGC
CTTACCCCGCCAATAGCGACGGCTATCACTACCTGCTCAAAACCCCTTTTCGTTACCCGCCATTGCGCTGGGGCTCGCGC
TTCGGGCGCATTCATGAACCGGGTATTTTTTACGCTGGCGGCAACGCCCACACCACGCTCGCTGAATCAGCCTTCTACCG
TTTTGTGTTTTGGTATTCGATGGCTGCATCACCCATTAAAAACACAATTACCTCCGCACACACACTATTCAGTGTGAATT
ACGCAAGTCAGCGAGGTGTGAAATTACAAGTTGCGCCGTTTGATCGCTTCGCACAGCAACTCACCGATCGCAAAGATTAT
TCTGCGACTCAACAACTCGGAAGCAATATGCGTGCGGCAAACGTCGAAGTCTTCGAATACCAATCGGCGCGTGATCCGCA
GCGGGGCCATTGCGTCGGCTTGTTTGTTCCTGCTGCACTCTCCCAAAAAAAGCCGGCCGACATGACCCAATGGTTATGCG
AGCTGGGCGCGTCTGAAGTTGCGTTCAAACAAGTGGGGCACAAAGAGATCATCCATTTTCCTGTTGATCTCTTTCTGGTG
GATGGTCGTTTGCCTATGCCGGCGGCCTGA

Antitoxin


Download         Length: 124 a.a.        Molecular weight: 13181.51 Da        Isoelectric Point: 10.8744

>AT109983 WP_151033392.1 NZ_CP031728:3930700-3931071 [Cellvibrio sp. KY-GH-1]
MSALVQTNPNPAAVLAKAVLNAADQLGLKQAELAAVLGIHRTAISRLKQNPALDPKSKQGELALLLIRIARALFALTGGD
KDWIKHFMHNPNQVTGGVPAKQMESIQGLMQVLNFVDALRGKI

Download         Length: 372 bp

>AT109983 NZ_CP031728:3930700-3931071 [Cellvibrio sp. KY-GH-1]
ATGTCAGCCCTTGTACAAACCAATCCCAACCCGGCCGCTGTACTCGCCAAGGCGGTATTGAATGCCGCCGATCAGCTCGG
GTTAAAACAAGCCGAGCTTGCCGCCGTACTGGGCATTCACCGCACCGCCATTAGCCGGCTCAAACAGAACCCTGCGCTGG
ACCCCAAATCCAAGCAGGGAGAATTGGCACTACTGCTGATCCGTATCGCCCGCGCACTCTTCGCACTAACTGGCGGCGAT
AAAGATTGGATCAAACACTTTATGCACAACCCCAATCAGGTAACCGGTGGTGTTCCGGCCAAGCAAATGGAATCTATTCA
GGGCCTGATGCAAGTGCTGAACTTTGTTGATGCCCTGCGCGGCAAGATTTAA

Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure

Antitoxin

Source ID Structure

References