Detailed information of TA system TA109982

Bioinformatically predicted

Overview

TA module

• Type: II
• Classification (family/domain): vapBC/PIN-MazE
• Location: 3847353..3847971
• Replicon: chromosome
• Accession: NZ_CP031728
• Organism: Cellvibrio sp. KY-GH-1

Toxin (Protein)

• Gene name: vapC
• Uniprot ID: -
• Locus tag: D0C16_RS16260
• Protein ID: WP_151033323.1
• Coordinates: 3847570..3847971 (+)
• Length: 134 a.a.

Antitoxin (Protein)

• Gene name: vapB
• Uniprot ID: -
• Locus tag: D0C16_RS16255
• Protein ID: WP_151033322.1
• Coordinates: 3847353..3847580 (+)
• Length: 76 a.a.

Genomic Context

Locus tag	Coordinates	Strand	Size (bp)	Protein ID	Product	Description
D0C16_RS16240	3845365..3846333	+	969	WP_151033319.1	chemotaxis protein CheB	-
D0C16_RS16245	3846375..3846857	+	483	WP_151033320.1	chemotaxis protein CheW	-
D0C16_RS16250	3846888..3847226	+	339	WP_151033321.1	FKBP-type peptidyl-prolyl cis-trans isomerase	-
D0C16_RS16255	3847353..3847580	+	228	WP_151033322.1	AbrB/MazE/SpoVT family DNA-binding domain-containing protein	Antitoxin
D0C16_RS16260	3847570..3847971	+	402	WP_151033323.1	PIN domain-containing protein	Toxin
D0C16_RS16265	3847990..3849123	+	1134	WP_151033324.1	SIR2 family protein	-
D0C16_RS16270	3849181..3849576	+	396	WP_191968516.1	hypothetical protein	-
D0C16_RS16275	3849584..3849862	-	279	WP_151033326.1	RsmE family RNA methyltransferase	-
D0C16_RS16280	3849951..3850735	+	785	Protein_3224	alpha/beta fold hydrolase	-
D0C16_RS16285	3850799..3851266	-	468	WP_151033327.1	DTW domain-containing protein	-
D0C16_RS16290	3851306..3851596	-	291	WP_151033328.1	peptidylprolyl isomerase	-
D0C16_RS16295	3851669..3852394	-	726	WP_151033329.1	16S rRNA (uracil(1498)-N(3))-methyltransferase	-

Associated MGEs

MGE detail	Similar MGEs	Relative position	MGE Type	Cargo ARG	Virulence gene	Coordinates	Length (bp)
	-	inside	Genomic island	-	-	3845365..3865917	20552

Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.

Domains

Predicted by InterproScan

Toxin

• PIN domain (5-115)

Antitoxin

• SpoVT-AbrB domain (5-34)

Sequences

Toxin

Protein

• Length: 134 a.a.
• Molecular weight: 14902.00 Da
• Isoelectric Point: 4.6339

>T109982 WP_151033323.1 NZ_CP031728:3847570-3847971 [Cellvibrio sp. KY-GH-1]
MRDRIFLDTNILVYVLLDEGPKQQTALELLQSGCVISTQVLNEFSQVARKKAKLEWQEISDLSHAIQTLTEVIPLTQEIH
NTALEIAAQYGYGFYDSLIIAAAHESQCNLLASGDMQNLQTIKQLAITNPFHT

Nucleotide

• Length: 402 bp

>T109982 NZ_CP031728:3847570-3847971 [Cellvibrio sp. KY-GH-1]
ATGAGAGATAGGATTTTTCTCGACACCAATATTCTGGTGTACGTCCTCTTGGACGAAGGCCCCAAACAACAAACCGCACT
CGAACTTCTCCAATCAGGTTGCGTTATCAGCACCCAAGTGCTGAATGAATTCAGTCAGGTCGCCCGCAAAAAAGCCAAGC
TCGAATGGCAAGAAATATCCGACCTCAGCCACGCCATCCAAACACTTACCGAAGTCATTCCACTTACACAAGAAATCCAC
AACACAGCGCTGGAAATTGCAGCGCAATATGGTTATGGGTTTTATGATTCGTTGATTATTGCCGCTGCGCATGAAAGCCA
ATGTAATTTGCTGGCATCGGGGGATATGCAAAACTTGCAAACGATAAAACAACTGGCAATAACTAACCCTTTCCACACTT
AA

Antitoxin

Protein

• Length: 76 a.a.
• Molecular weight: 8486.74 Da
• Isoelectric Point: 10.3120

>AT109982 WP_151033322.1 NZ_CP031728:3847353-3847580 [Cellvibrio sp. KY-GH-1]
MQIAKWGNSLAIRIPANVAKSLELKAGDEVEIVASPTGFEVIKDDRKSKALETLNRFKGRLPKNFTFNRDELNER

Nucleotide

• Length: 228 bp

>AT109982 NZ_CP031728:3847353-3847580 [Cellvibrio sp. KY-GH-1]
ATGCAAATCGCCAAATGGGGCAATAGCCTCGCCATTCGCATCCCTGCGAATGTCGCCAAATCGCTCGAACTTAAAGCCGG
TGATGAAGTTGAAATTGTGGCATCCCCCACCGGCTTTGAAGTCATCAAAGACGATCGCAAAAGCAAAGCACTGGAAACCC
TCAACCGCTTCAAAGGTCGTTTGCCCAAAAATTTTACATTTAATCGGGATGAATTGAATGAGAGATAG