Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type II Classification (family/domain) vapBC/PIN-MazE
Location 3847353..3847971 Replicon chromosome
Accession NZ_CP031728
Organism Cellvibrio sp. KY-GH-1

Toxin (Protein)


Gene name vapC Uniprot ID -
Locus tag D0C16_RS16260 Protein ID WP_151033323.1
Coordinates 3847570..3847971 (+) Length 134 a.a.

Antitoxin (Protein)


Gene name vapB Uniprot ID -
Locus tag D0C16_RS16255 Protein ID WP_151033322.1
Coordinates 3847353..3847580 (+) Length 76 a.a.

Genomic Context

D0C16_RS16240D0C16_RS16245D0C16_RS16250D0C16_RS16255D0C16_RS16260D0C16_RS16265D0C16_RS16270D0C16_RS16280D0C16_RS16275D0C16_RS16285D0C16_RS16290D0C16_RS16295
Location: 3845365..3846333 (969 bp)
Type: Others
Protein ID: WP_151033319.1
Location: 3846375..3846857 (483 bp)
Type: Others
Protein ID: WP_151033320.1
Location: 3846888..3847226 (339 bp)
Type: Others
Protein ID: WP_151033321.1
Location: 3847353..3847580 (228 bp)
Type: Antitoxin
Protein ID: WP_151033322.1
Location: 3847570..3847971 (402 bp)
Type: Toxin
Protein ID: WP_151033323.1
Location: 3847990..3849123 (1134 bp)
Type: Others
Protein ID: WP_151033324.1
Location: 3849181..3849576 (396 bp)
Type: Others
Protein ID: WP_191968516.1
Location: 3849951..3850735 (785 bp)
Type: Others
Protein ID: Protein_3224
Location: 3849584..3849862 (279 bp)
Type: Others
Protein ID: WP_151033326.1
Location: 3850799..3851266 (468 bp)
Type: Others
Protein ID: WP_151033327.1
Location: 3851306..3851596 (291 bp)
Type: Others
Protein ID: WP_151033328.1
Location: 3851669..3852394 (726 bp)
Type: Others
Protein ID: WP_151033329.1
ToxinAntitoxinOther genes
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Locus tag
Coordinates
Strand
Size (bp)
Protein ID
Product
Description
D0C16_RS162403845365..3846333+969WP_151033319.1chemotaxis protein CheB-
D0C16_RS162453846375..3846857+483WP_151033320.1chemotaxis protein CheW-
D0C16_RS162503846888..3847226+339WP_151033321.1FKBP-type peptidyl-prolyl cis-trans isomerase-
D0C16_RS162553847353..3847580+228WP_151033322.1AbrB/MazE/SpoVT family DNA-binding domain-containing proteinAntitoxin
D0C16_RS162603847570..3847971+402WP_151033323.1PIN domain-containing proteinToxin
D0C16_RS162653847990..3849123+1134WP_151033324.1SIR2 family protein-
D0C16_RS162703849181..3849576+396WP_191968516.1hypothetical protein-
D0C16_RS162753849584..3849862-279WP_151033326.1RsmE family RNA methyltransferase-
D0C16_RS162803849951..3850735+785Protein_3224alpha/beta fold hydrolase-
D0C16_RS162853850799..3851266-468WP_151033327.1DTW domain-containing protein-
D0C16_RS162903851306..3851596-291WP_151033328.1peptidylprolyl isomerase-
D0C16_RS162953851669..3852394-726WP_151033329.116S rRNA (uracil(1498)-N(3))-methyltransferase-

Associated MGEs

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MGE
detail
Similar
MGEs
Relative
position
MGE Type
Cargo ARG
Virulence gene
Coordinates
Length (bp)
-insideGenomic island--3845365..386591720552


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin

PIN domain

(5-115)

Antitoxin

SpoVT-AbrB domain

(5-34)


Sequences

Toxin        


Download         Length: 134 a.a.        Molecular weight: 14902.00 Da        Isoelectric Point: 4.6339

>T109982 WP_151033323.1 NZ_CP031728:3847570-3847971 [Cellvibrio sp. KY-GH-1]
MRDRIFLDTNILVYVLLDEGPKQQTALELLQSGCVISTQVLNEFSQVARKKAKLEWQEISDLSHAIQTLTEVIPLTQEIH
NTALEIAAQYGYGFYDSLIIAAAHESQCNLLASGDMQNLQTIKQLAITNPFHT

Download         Length: 402 bp

>T109982 NZ_CP031728:3847570-3847971 [Cellvibrio sp. KY-GH-1]
ATGAGAGATAGGATTTTTCTCGACACCAATATTCTGGTGTACGTCCTCTTGGACGAAGGCCCCAAACAACAAACCGCACT
CGAACTTCTCCAATCAGGTTGCGTTATCAGCACCCAAGTGCTGAATGAATTCAGTCAGGTCGCCCGCAAAAAAGCCAAGC
TCGAATGGCAAGAAATATCCGACCTCAGCCACGCCATCCAAACACTTACCGAAGTCATTCCACTTACACAAGAAATCCAC
AACACAGCGCTGGAAATTGCAGCGCAATATGGTTATGGGTTTTATGATTCGTTGATTATTGCCGCTGCGCATGAAAGCCA
ATGTAATTTGCTGGCATCGGGGGATATGCAAAACTTGCAAACGATAAAACAACTGGCAATAACTAACCCTTTCCACACTT
AA

Antitoxin


Download         Length: 76 a.a.        Molecular weight: 8486.74 Da        Isoelectric Point: 10.3120

>AT109982 WP_151033322.1 NZ_CP031728:3847353-3847580 [Cellvibrio sp. KY-GH-1]
MQIAKWGNSLAIRIPANVAKSLELKAGDEVEIVASPTGFEVIKDDRKSKALETLNRFKGRLPKNFTFNRDELNER

Download         Length: 228 bp

>AT109982 NZ_CP031728:3847353-3847580 [Cellvibrio sp. KY-GH-1]
ATGCAAATCGCCAAATGGGGCAATAGCCTCGCCATTCGCATCCCTGCGAATGTCGCCAAATCGCTCGAACTTAAAGCCGG
TGATGAAGTTGAAATTGTGGCATCCCCCACCGGCTTTGAAGTCATCAAAGACGATCGCAAAAGCAAAGCACTGGAAACCC
TCAACCGCTTCAAAGGTCGTTTGCCCAAAAATTTTACATTTAATCGGGATGAATTGAATGAGAGATAG

Similar Proteins

Only experimentally validated proteins are listed.

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Protein
Organism
Identities (%)
Coverage (%)
Ha-value
No matching records found
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Protein
Organism
Identities (%)
Coverage (%)
Ha-value
No matching records found

Structures

Toxin

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Source
ID
Structure
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Antitoxin

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Source
ID
Structure
No matching records found

References