Detailed information of TA system TA109980

Bioinformatically predicted

Overview

TA module

• Type: II
• Classification (family/domain): relBE/YoeB-RelB
• Location: 1790959..1791464
• Replicon: chromosome
• Accession: NZ_CP031728
• Organism: Cellvibrio sp. KY-GH-1

Toxin (Protein)

• Gene name: relB
• Uniprot ID: -
• Locus tag: D0C16_RS07555
• Protein ID: WP_151031746.1
• Coordinates: 1790959..1791213 (-)
• Length: 85 a.a.

Antitoxin (Protein)

• Gene name: relE
• Uniprot ID: -
• Locus tag: D0C16_RS07560
• Protein ID: WP_151031747.1
• Coordinates: 1791210..1791464 (-)
• Length: 85 a.a.

Genomic Context

Locus tag	Coordinates	Strand	Size (bp)	Protein ID	Product	Description
D0C16_RS07540	1787185..1788378	+	1194	WP_151031744.1	MFS transporter	-
D0C16_RS07545	1788600..1789946	-	1347	Protein_1493	IS1182 family transposase	-
D0C16_RS07550	1790057..1790917	-	861	WP_151031745.1	formyltetrahydrofolate deformylase	-
D0C16_RS07555	1790959..1791213	-	255	WP_151031746.1	Txe/YoeB family addiction module toxin	Toxin
D0C16_RS07560	1791210..1791464	-	255	WP_151031747.1	type II toxin-antitoxin system prevent-host-death family antitoxin	Antitoxin
D0C16_RS07565	1791636..1792058	+	423	WP_151031748.1	DUF1780 domain-containing protein	-
D0C16_RS07570	1792301..1793092	-	792	WP_151031749.1	hypothetical protein	-
D0C16_RS07580	1793631..1794122	+	492	WP_151031750.1	hypothetical protein	-
D0C16_RS07585	1794139..1794951	+	813	WP_151031751.1	peptidoglycan-binding protein	-
D0C16_RS07590	1795097..1796194	-	1098	WP_151031752.1	NADH:flavin oxidoreductase/NADH oxidase	-

Associated MGEs

MGE detail	Similar MGEs	Relative position	MGE Type	Cargo ARG	Virulence gene	Coordinates	Length (bp)

Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.

Domains

Predicted by InterproScan

Toxin

• Toxin YoeB (5-84)

Antitoxin

• Type II toxin-antitoxin system, antitoxin Phd/YefM (1-73)

Sequences

Toxin

Protein

• Length: 85 a.a.
• Molecular weight: 10429.94 Da
• Isoelectric Point: 8.8109

>T109980 WP_151031746.1 NZ_CP031728:c1791213-1790959 [Cellvibrio sp. KY-GH-1]
MILAWADHAWEDYLYWQKADMKTLKRINTLVKEIQRQPFAGIGDPEPLKHHWSGYWSRRIDREYRLVYRVENETIFVVQC
RYHY

Nucleotide

• Length: 255 bp

>T109980 NZ_CP031728:c1791213-1790959 [Cellvibrio sp. KY-GH-1]
ATGATTCTGGCGTGGGCGGATCATGCCTGGGAGGATTACCTCTACTGGCAAAAAGCCGATATGAAAACTCTTAAGCGCAT
TAATACCCTTGTTAAAGAGATCCAGCGCCAGCCGTTTGCTGGAATAGGCGACCCGGAACCGCTGAAGCATCATTGGTCGG
GTTATTGGTCGCGGCGGATTGATCGCGAGTATCGACTGGTTTATCGCGTTGAGAATGAAACTATCTTTGTGGTGCAATGC
CGTTATCACTATTGA

Antitoxin

Protein

• Length: 85 a.a.
• Molecular weight: 9268.46 Da
• Isoelectric Point: 4.7045

>AT109980 WP_151031747.1 NZ_CP031728:c1791464-1791210 [Cellvibrio sp. KY-GH-1]
MDTMSYTAFRNDLASVLDKVNDDHKPVLITRQNGKPAVVISLEDFQAYEETAYLMASPKNAVRLNDSINQVAAGKATPRG
LIEE

Nucleotide

• Length: 255 bp

>AT109980 NZ_CP031728:c1791464-1791210 [Cellvibrio sp. KY-GH-1]
ATGGATACCATGAGCTATACCGCCTTTCGCAATGATCTAGCCAGTGTGCTGGATAAGGTGAACGATGATCATAAGCCGGT
ACTAATTACCCGTCAGAACGGTAAGCCGGCGGTGGTGATTAGCCTGGAAGATTTTCAGGCCTATGAGGAAACTGCCTATT
TGATGGCTAGCCCTAAAAATGCTGTGCGCTTGAATGATTCGATTAACCAGGTGGCCGCTGGGAAGGCTACGCCGCGGGGG
TTAATCGAGGAATGA