Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type II Classification (family/domain) tacT-ataR/DUF1778(antitoxin)
Location 140487..141238 Replicon chromosome
Accession NZ_CP031728
Organism Cellvibrio sp. KY-GH-1

Toxin (Protein)


Gene name tacT Uniprot ID -
Locus tag D0C16_RS00485 Protein ID WP_151030521.1
Coordinates 140487..140990 (-) Length 168 a.a.

Antitoxin (Protein)


Gene name ataR Uniprot ID -
Locus tag D0C16_RS00490 Protein ID WP_151030522.1
Coordinates 140972..141238 (-) Length 89 a.a.

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
D0C16_RS00465 135926..136102 - 177 WP_151030517.1 YezD family protein -
D0C16_RS00470 136508..137530 - 1023 WP_151030518.1 sulfate ABC transporter substrate-binding protein -
D0C16_RS00475 138243..139241 + 999 WP_151030519.1 SMP-30/gluconolactonase/LRE family protein -
D0C16_RS00480 139394..140287 + 894 WP_151030520.1 dienelactone hydrolase family protein -
D0C16_RS00485 140487..140990 - 504 WP_151030521.1 GNAT family N-acetyltransferase Toxin
D0C16_RS00490 140972..141238 - 267 WP_151030522.1 DUF1778 domain-containing protein Antitoxin
D0C16_RS00495 141454..141777 + 324 WP_151030523.1 GntR family transcriptional regulator -
D0C16_RS00500 141792..142700 + 909 WP_151030524.1 ABC transporter ATP-binding protein -
D0C16_RS00505 142697..143386 + 690 WP_151030525.1 hypothetical protein -
D0C16_RS00510 143657..144136 + 480 WP_151030526.1 rhodanese-like domain-containing protein -
D0C16_RS00515 144265..145533 - 1269 WP_151030527.1 efflux RND transporter periplasmic adaptor subunit -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin

GNAT domain

(47-148)

Antitoxin

Vibrio phage ICP1, Orf50

(3-88)


Sequences

Toxin        


Download         Length: 168 a.a.        Molecular weight: 17981.87 Da        Isoelectric Point: 10.2251

>T109979 WP_151030521.1 NZ_CP031728:c140990-140487 [Cellvibrio sp. KY-GH-1]
IALGKITAPGLLASTHELGNFNSGNSTLDEWLIRRALKNQESGASRTFVICEDGSRVIGYYALATGSIERISAAGSFSRG
MPDPIPVIILGRLAVDIKFQGKRLGAALLKDAMLRTLAIASNVGVRGLLVHAISEQAKQFYLQYGFQKSPTDPMTLLLSL
KNISQHL

Download         Length: 504 bp

>T109979 NZ_CP031728:c140990-140487 [Cellvibrio sp. KY-GH-1]
ATCGCCTTGGGAAAAATAACAGCACCTGGCCTACTCGCCTCCACACATGAATTAGGAAATTTTAATAGCGGAAATAGCAC
ACTGGATGAGTGGCTTATTCGCAGGGCTTTAAAGAATCAGGAAAGCGGTGCAAGCAGAACATTCGTTATTTGTGAAGATG
GCTCAAGGGTTATCGGCTACTACGCACTTGCCACAGGAAGTATCGAAAGAATTTCAGCAGCGGGAAGTTTTTCTCGCGGA
ATGCCAGATCCTATTCCCGTTATCATTCTCGGACGTCTTGCGGTTGACATAAAATTTCAAGGGAAACGCCTTGGAGCCGC
CCTGCTAAAAGATGCAATGTTAAGGACACTCGCTATTGCTAGTAATGTAGGGGTGAGAGGGTTACTAGTACATGCAATAT
CAGAGCAAGCGAAGCAATTTTATTTACAATATGGATTCCAGAAATCCCCGACTGATCCTATGACTTTGCTTCTTTCACTT
AAAAATATAAGCCAACATTTGTAA

Antitoxin


Download         Length: 89 a.a.        Molecular weight: 9935.41 Da        Isoelectric Point: 5.1297

>AT109979 WP_151030522.1 NZ_CP031728:c141238-140972 [Cellvibrio sp. KY-GH-1]
MSRTAPINMRVEPSQHALLTKAAALLNKDRSAFILDVACREAENVLLDQRLLQFNDKDFKDFEAALTAPIPENAKLKALL
NEESPWEK

Download         Length: 267 bp

>AT109979 NZ_CP031728:c141238-140972 [Cellvibrio sp. KY-GH-1]
ATGTCTAGAACAGCACCAATCAATATGCGTGTTGAACCCAGTCAACACGCCTTATTAACCAAAGCCGCAGCACTGCTAAA
CAAAGACAGAAGTGCATTTATTTTGGATGTCGCTTGCAGGGAAGCGGAGAATGTCCTCCTCGACCAACGCTTGCTGCAAT
TTAACGATAAAGATTTTAAAGATTTTGAAGCGGCGTTAACGGCCCCGATTCCAGAAAATGCAAAGTTGAAAGCGCTGCTG
AATGAGGAATCGCCTTGGGAAAAATAA

Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure

Antitoxin

Source ID Structure

References