Detailed information of TA system    

insolicoBioinformatically predicted

Overview


TA module


Type VIII Classification (family/domain) SdsR-RyeA/-
Location 2043916..2044061 Replicon chromosome
Accession NZ_CP031721
Organism Klebsiella pneumoniae strain SCKP020003

Toxin (RNA)


Gene name SdsR
Locus tag -
Coordinates 2043952..2044054 (+)

Antitoxin (RNA)


Gene name RyeA
Locus tag -
Coordinates 2043916..2044061 (-)

Genomic Context


Locus tag Coordinates Strand Size (bp) Protein ID Product Description
CAY64_RS11730 2039046..2041106 + 2061 WP_004151449.1 oligopeptidase B -
CAY64_RS11735 2041110..2041769 - 660 WP_002911407.1 exodeoxyribonuclease X -
CAY64_RS11740 2041848..2042078 - 231 WP_002911406.1 DNA polymerase III subunit theta -
CAY64_RS11745 2042191..2042565 + 375 WP_004151448.1 CopC domain-containing protein YobA -
CAY64_RS11750 2042569..2043438 + 870 WP_062955019.1 copper homeostasis membrane protein CopD -
CAY64_RS11755 2043455..2043793 + 339 WP_002911404.1 YebY family protein -
- 2043916..2044061 - 146 - - Antitoxin
- 2043952..2044054 + 103 - - Toxin
CAY64_RS29000 2044429..2044572 - 144 WP_002911398.1 Ecr family regulatory small membrane protein -
CAY64_RS11765 2044677..2045645 - 969 WP_004151446.1 VirK/YbjX family protein -
CAY64_RS11770 2045802..2046455 + 654 WP_004180432.1 protein-serine/threonine phosphatase -
CAY64_RS11775 2046452..2046643 - 192 WP_002911395.1 YebW family protein -
CAY64_RS11780 2046741..2046980 - 240 WP_002911393.1 YebV family protein -
CAY64_RS11785 2047096..2048529 - 1434 WP_004148845.1 16S rRNA (cytosine(1407)-C(5))-methyltransferase RsmF -

Associated MGEs


MGE
detail
Similar
MGEs
Relative
position
MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Sequences


Toxin        


Download         Length: 103 bp

>T109945 NZ_CP031721:2043952-2044054 [Klebsiella pneumoniae]
GCAAGGCGACTTAGCCTGCATTAATGCCAACTTTTAGCGCACGGCTCTCTCCCAAGAGCCATTTCCCTGGACCGAATACA
GGAATCGTATTCGGTCTCTTTTT

Antitoxin


Download         Length: 146 bp

>AT109945 NZ_CP031721:c2044061-2043916 [Klebsiella pneumoniae]
TAAAGATAAAAAGAGACCGAATACGATTCCTGTATTCGGTCCAGGGAAATGGCTCTTGGGAGAGAGCCGTGCGCTAAAAG
TTGGCATTAATGCAGGCTAAGTCGCCTTGCACTATAAGAATAGTTTAACGCGTCAGCTTTTCCAGT

Structures


Antitoxin

Download structure file

Antitoxin

Download structure file

References