Detailed information of TA system
Bioinformatically predictedOverview
TA module
Type | II | Classification (family/domain) | relE-paaA/RelE(toxin) |
Location | 3018936..3019386 | Replicon | chromosome |
Accession | NZ_CP031716 | ||
Organism | Acinetobacter wuhouensis strain WCHA60 |
Toxin (Protein)
Gene name | relE | Uniprot ID | A0A385C6N3 |
Locus tag | BEN71_RS15015 | Protein ID | WP_068974807.1 |
Coordinates | 3019111..3019386 (+) | Length | 92 a.a. |
Antitoxin (Protein)
Gene name | paaA | Uniprot ID | A0A385C6H6 |
Locus tag | BEN71_RS15010 | Protein ID | WP_068974806.1 |
Coordinates | 3018936..3019124 (+) | Length | 63 a.a. |
Genomic Context
Locus tag | Coordinates | Strand | Size (bp) | Protein ID | Product | Description |
---|---|---|---|---|---|---|
BEN71_RS14970 | 3014332..3015627 | - | 1296 | WP_068974798.1 | iron-sulfur cluster carrier protein ApbC | - |
BEN71_RS14975 | 3016112..3016405 | - | 294 | WP_068974799.1 | hypothetical protein | - |
BEN71_RS14980 | 3016544..3016843 | + | 300 | WP_068974800.1 | hypothetical protein | - |
BEN71_RS14985 | 3016889..3017077 | - | 189 | WP_068974801.1 | hypothetical protein | - |
BEN71_RS14990 | 3017286..3017510 | + | 225 | WP_068974802.1 | hypothetical protein | - |
BEN71_RS14995 | 3017500..3017847 | + | 348 | WP_068974803.1 | hypothetical protein | - |
BEN71_RS15000 | 3017858..3018172 | - | 315 | WP_068974804.1 | antibiotic biosynthesis monooxygenase | - |
BEN71_RS15005 | 3018227..3018742 | - | 516 | WP_068974805.1 | hypothetical protein | - |
BEN71_RS15010 | 3018936..3019124 | + | 189 | WP_068974806.1 | antitoxin | Antitoxin |
BEN71_RS15015 | 3019111..3019386 | + | 276 | WP_068974807.1 | type II toxin-antitoxin system RelE/ParE family toxin | Toxin |
BEN71_RS15020 | 3019419..3020249 | - | 831 | WP_068974821.1 | hypothetical protein | - |
BEN71_RS15025 | 3020440..3022497 | + | 2058 | WP_068974808.1 | methionine--tRNA ligase | - |
BEN71_RS15030 | 3023210..3024001 | + | 792 | WP_068974809.1 | segregation/condensation protein A | - |
Associated MGEs
MGE detail |
Similar MGEs |
Relative position |
MGE Type | Cargo ARG | Virulence gene | Coordinates | Length (bp) |
---|
Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.
Sequences
Toxin
Download Length: 92 a.a. Molecular weight: 10510.09 Da Isoelectric Point: 5.0233
>T109929 WP_068974807.1 NZ_CP031716:3019111-3019386 [Acinetobacter wuhouensis]
MLTVNWKINAVHDLEEIIDYIFIQNPGAAINLEDEILNTAESLADMPYSGRIGRVSGTRERIVHPNYMIIYQLLFDSIEI
LNIVHTKKHYP
MLTVNWKINAVHDLEEIIDYIFIQNPGAAINLEDEILNTAESLADMPYSGRIGRVSGTRERIVHPNYMIIYQLLFDSIEI
LNIVHTKKHYP
Download Length: 276 bp
>T109929 NZ_CP031716:3019111-3019386 [Acinetobacter wuhouensis]
ATGTTGACCGTTAACTGGAAAATAAACGCTGTTCATGACTTAGAGGAAATTATTGATTATATTTTCATTCAAAACCCTGG
AGCCGCAATAAATCTCGAAGATGAAATTTTAAATACGGCTGAGAGCCTTGCTGATATGCCATACAGTGGGCGTATAGGTC
GAGTTTCTGGGACGAGAGAAAGGATCGTACATCCCAATTACATGATTATTTATCAGCTTTTATTTGATTCAATTGAAATT
CTCAATATCGTACATACAAAAAAGCATTATCCATAA
ATGTTGACCGTTAACTGGAAAATAAACGCTGTTCATGACTTAGAGGAAATTATTGATTATATTTTCATTCAAAACCCTGG
AGCCGCAATAAATCTCGAAGATGAAATTTTAAATACGGCTGAGAGCCTTGCTGATATGCCATACAGTGGGCGTATAGGTC
GAGTTTCTGGGACGAGAGAAAGGATCGTACATCCCAATTACATGATTATTTATCAGCTTTTATTTGATTCAATTGAAATT
CTCAATATCGTACATACAAAAAAGCATTATCCATAA
Antitoxin
Download Length: 63 a.a. Molecular weight: 7544.34 Da Isoelectric Point: 4.4678
>AT109929 WP_068974806.1 NZ_CP031716:3018936-3019124 [Acinetobacter wuhouensis]
MNEVFDPFVSEFDDADMEQNYNEWLKNKVEQSIVDSRPSISHDQVIERMKQKREERLKNVDR
MNEVFDPFVSEFDDADMEQNYNEWLKNKVEQSIVDSRPSISHDQVIERMKQKREERLKNVDR
Download Length: 189 bp
>AT109929 NZ_CP031716:3018936-3019124 [Acinetobacter wuhouensis]
ATGAATGAAGTATTTGATCCTTTCGTGTCAGAATTTGACGATGCGGATATGGAACAAAATTACAATGAATGGCTGAAAAA
CAAAGTTGAACAGTCTATTGTCGATTCACGCCCATCCATTTCACATGATCAAGTTATTGAACGCATGAAGCAAAAGCGCG
AAGAAAGATTAAAAAATGTTGACCGTTAA
ATGAATGAAGTATTTGATCCTTTCGTGTCAGAATTTGACGATGCGGATATGGAACAAAATTACAATGAATGGCTGAAAAA
CAAAGTTGAACAGTCTATTGTCGATTCACGCCCATCCATTTCACATGATCAAGTTATTGAACGCATGAAGCAAAAGCGCG
AAGAAAGATTAAAAAATGTTGACCGTTAA
Similar Proteins
Only experimentally validated proteins are listed.
Protein | Organism | Identities (%) | Coverage (%) | Ha-value |
---|
Protein | Organism | Identities (%) | Coverage (%) | Ha-value |
---|
Structures
Toxin
Source | ID | Structure |
---|---|---|
AlphaFold DB | A0A385C6N3 |
Antitoxin
Source | ID | Structure |
---|---|---|
AlphaFold DB | A0A385C6H6 |