Detailed information of TA system
Bioinformatically predictedOverview
TA module
Type | II | Classification (family/domain) | relBE/RelB-YoeB |
Location | 2117064..2117572 | Replicon | chromosome |
Accession | NZ_CP031716 | ||
Organism | Acinetobacter wuhouensis strain WCHA60 |
Toxin (Protein)
Gene name | relE | Uniprot ID | A0A385C4A1 |
Locus tag | BEN71_RS10785 | Protein ID | WP_068974289.1 |
Coordinates | 2117064..2117318 (+) | Length | 85 a.a. |
Antitoxin (Protein)
Gene name | relB | Uniprot ID | A0A385C6L9 |
Locus tag | BEN71_RS10790 | Protein ID | WP_068974290.1 |
Coordinates | 2117315..2117572 (+) | Length | 86 a.a. |
Genomic Context
Locus tag | Coordinates | Strand | Size (bp) | Protein ID | Product | Description |
---|---|---|---|---|---|---|
BEN71_RS10765 | 2112921..2114189 | - | 1269 | WP_068974285.1 | D-amino acid dehydrogenase | - |
BEN71_RS10770 | 2114444..2115580 | - | 1137 | WP_068974286.1 | rod shape-determining protein RodA | - |
BEN71_RS10775 | 2115680..2116396 | - | 717 | WP_068974287.1 | 2-C-methyl-D-erythritol 4-phosphate cytidylyltransferase | - |
BEN71_RS10780 | 2116362..2116748 | - | 387 | WP_068974288.1 | cell division protein FtsB | - |
BEN71_RS10785 | 2117064..2117318 | + | 255 | WP_068974289.1 | type II toxin-antitoxin system prevent-host-death family antitoxin | Toxin |
BEN71_RS10790 | 2117315..2117572 | + | 258 | WP_068974290.1 | Txe/YoeB family addiction module toxin | Antitoxin |
BEN71_RS10795 | 2117663..2118952 | - | 1290 | WP_068974291.1 | phosphopyruvate hydratase | - |
BEN71_RS10800 | 2119017..2119874 | - | 858 | WP_068974292.1 | 3-deoxy-8-phosphooctulonate synthase | - |
BEN71_RS10805 | 2119902..2121542 | - | 1641 | WP_068974293.1 | CTP synthase | - |
BEN71_RS10810 | 2121771..2122247 | + | 477 | WP_068974294.1 | internalin | - |
Associated MGEs
MGE detail |
Similar MGEs |
Relative position |
MGE Type | Cargo ARG | Virulence gene | Coordinates | Length (bp) |
---|
Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.
Sequences
Toxin
Download Length: 85 a.a. Molecular weight: 9400.63 Da Isoelectric Point: 5.0618
>T109927 WP_068974289.1 NZ_CP031716:2117064-2117318 [Acinetobacter wuhouensis]
MKIVTYSDLRKNLATVLDGVIDDHSPVLVTRQNNQTAVLISLEDFNAYEETAHLLKSPANAKRLRDSIAQIEAGKTINHE
LIEE
MKIVTYSDLRKNLATVLDGVIDDHSPVLVTRQNNQTAVLISLEDFNAYEETAHLLKSPANAKRLRDSIAQIEAGKTINHE
LIEE
Download Length: 255 bp
>T109927 NZ_CP031716:2117064-2117318 [Acinetobacter wuhouensis]
ATGAAAATTGTTACATATTCGGATCTTCGTAAAAACTTAGCAACTGTATTAGATGGTGTCATTGATGATCATTCCCCTGT
ACTAGTGACTCGGCAAAATAATCAAACAGCCGTCTTGATCAGCTTAGAAGATTTTAATGCCTATGAAGAAACAGCCCATT
TGCTAAAAAGCCCTGCGAATGCAAAAAGATTGCGTGATTCAATTGCACAAATTGAAGCAGGTAAAACAATAAACCATGAG
CTGATTGAAGAATGA
ATGAAAATTGTTACATATTCGGATCTTCGTAAAAACTTAGCAACTGTATTAGATGGTGTCATTGATGATCATTCCCCTGT
ACTAGTGACTCGGCAAAATAATCAAACAGCCGTCTTGATCAGCTTAGAAGATTTTAATGCCTATGAAGAAACAGCCCATT
TGCTAAAAAGCCCTGCGAATGCAAAAAGATTGCGTGATTCAATTGCACAAATTGAAGCAGGTAAAACAATAAACCATGAG
CTGATTGAAGAATGA
Antitoxin
Download Length: 86 a.a. Molecular weight: 10283.77 Da Isoelectric Point: 8.8170
>AT109927 WP_068974290.1 NZ_CP031716:2117315-2117572 [Acinetobacter wuhouensis]
MILSWSNEAWEDYLYWQSTDKQTLKRINTLIKDIKRSPFDGVGKPEPLKHDLSGYWSRRIDKENRIVYKVTTESIIIVMC
RYHYD
MILSWSNEAWEDYLYWQSTDKQTLKRINTLIKDIKRSPFDGVGKPEPLKHDLSGYWSRRIDKENRIVYKVTTESIIIVMC
RYHYD
Download Length: 258 bp
>AT109927 NZ_CP031716:2117315-2117572 [Acinetobacter wuhouensis]
ATGATTTTAAGTTGGAGCAATGAGGCTTGGGAGGATTACCTTTATTGGCAATCTACGGATAAACAAACACTCAAAAGAAT
TAATACATTGATAAAAGACATTAAACGATCACCATTTGATGGAGTTGGCAAACCAGAACCTCTCAAACATGATCTCAGTG
GTTATTGGTCAAGACGCATTGATAAAGAAAATCGCATCGTTTATAAAGTCACAACAGAATCAATTATTATTGTGATGTGC
CGTTATCATTATGATTAA
ATGATTTTAAGTTGGAGCAATGAGGCTTGGGAGGATTACCTTTATTGGCAATCTACGGATAAACAAACACTCAAAAGAAT
TAATACATTGATAAAAGACATTAAACGATCACCATTTGATGGAGTTGGCAAACCAGAACCTCTCAAACATGATCTCAGTG
GTTATTGGTCAAGACGCATTGATAAAGAAAATCGCATCGTTTATAAAGTCACAACAGAATCAATTATTATTGTGATGTGC
CGTTATCATTATGATTAA
Similar Proteins
Only experimentally validated proteins are listed.
Protein | Organism | Identities (%) | Coverage (%) | Ha-value |
---|
Protein | Organism | Identities (%) | Coverage (%) | Ha-value |
---|
Structures
Toxin
Source | ID | Structure |
---|---|---|
AlphaFold DB | A0A385C4A1 |
Antitoxin
Source | ID | Structure |
---|---|---|
AlphaFold DB | A0A385C6L9 |