109927

Detailed information of TA system    

insolicoBioinformatically predicted

Overview


TA module


Type II Classification (family/domain) relBE/RelB-YoeB
Location 2117064..2117572 Replicon chromosome
Accession NZ_CP031716
Organism Acinetobacter wuhouensis strain WCHA60

Toxin (Protein)


Gene name relE Uniprot ID A0A385C4A1
Locus tag BEN71_RS10785 Protein ID WP_068974289.1
Coordinates 2117064..2117318 (+) Length 85 a.a.

Antitoxin (Protein)


Gene name relB Uniprot ID A0A385C6L9
Locus tag BEN71_RS10790 Protein ID WP_068974290.1
Coordinates 2117315..2117572 (+) Length 86 a.a.

Genomic Context


Locus tag Coordinates Strand Size (bp) Protein ID Product Description
BEN71_RS10765 2112921..2114189 - 1269 WP_068974285.1 D-amino acid dehydrogenase -
BEN71_RS10770 2114444..2115580 - 1137 WP_068974286.1 rod shape-determining protein RodA -
BEN71_RS10775 2115680..2116396 - 717 WP_068974287.1 2-C-methyl-D-erythritol 4-phosphate cytidylyltransferase -
BEN71_RS10780 2116362..2116748 - 387 WP_068974288.1 cell division protein FtsB -
BEN71_RS10785 2117064..2117318 + 255 WP_068974289.1 type II toxin-antitoxin system prevent-host-death family antitoxin Toxin
BEN71_RS10790 2117315..2117572 + 258 WP_068974290.1 Txe/YoeB family addiction module toxin Antitoxin
BEN71_RS10795 2117663..2118952 - 1290 WP_068974291.1 phosphopyruvate hydratase -
BEN71_RS10800 2119017..2119874 - 858 WP_068974292.1 3-deoxy-8-phosphooctulonate synthase -
BEN71_RS10805 2119902..2121542 - 1641 WP_068974293.1 CTP synthase -
BEN71_RS10810 2121771..2122247 + 477 WP_068974294.1 internalin -

Associated MGEs


MGE
detail
Similar
MGEs
Relative
position
MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains


Predicted by InterproScan

Toxin

(1-74)

Antitoxin

(1-84)


Sequences


Toxin        


Download         Length: 85 a.a.        Molecular weight: 9400.63 Da        Isoelectric Point: 5.0618

>T109927 WP_068974289.1 NZ_CP031716:2117064-2117318 [Acinetobacter wuhouensis]
MKIVTYSDLRKNLATVLDGVIDDHSPVLVTRQNNQTAVLISLEDFNAYEETAHLLKSPANAKRLRDSIAQIEAGKTINHE
LIEE

Download         Length: 255 bp

>T109927 NZ_CP031716:2117064-2117318 [Acinetobacter wuhouensis]
ATGAAAATTGTTACATATTCGGATCTTCGTAAAAACTTAGCAACTGTATTAGATGGTGTCATTGATGATCATTCCCCTGT
ACTAGTGACTCGGCAAAATAATCAAACAGCCGTCTTGATCAGCTTAGAAGATTTTAATGCCTATGAAGAAACAGCCCATT
TGCTAAAAAGCCCTGCGAATGCAAAAAGATTGCGTGATTCAATTGCACAAATTGAAGCAGGTAAAACAATAAACCATGAG
CTGATTGAAGAATGA

Antitoxin


Download         Length: 86 a.a.        Molecular weight: 10283.77 Da        Isoelectric Point: 8.8170

>AT109927 WP_068974290.1 NZ_CP031716:2117315-2117572 [Acinetobacter wuhouensis]
MILSWSNEAWEDYLYWQSTDKQTLKRINTLIKDIKRSPFDGVGKPEPLKHDLSGYWSRRIDKENRIVYKVTTESIIIVMC
RYHYD

Download         Length: 258 bp

>AT109927 NZ_CP031716:2117315-2117572 [Acinetobacter wuhouensis]
ATGATTTTAAGTTGGAGCAATGAGGCTTGGGAGGATTACCTTTATTGGCAATCTACGGATAAACAAACACTCAAAAGAAT
TAATACATTGATAAAAGACATTAAACGATCACCATTTGATGGAGTTGGCAAACCAGAACCTCTCAAACATGATCTCAGTG
GTTATTGGTCAAGACGCATTGATAAAGAAAATCGCATCGTTTATAAAGTCACAACAGAATCAATTATTATTGTGATGTGC
CGTTATCATTATGATTAA

Similar Proteins


Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures


Toxin

Source ID Structure
AlphaFold DB A0A385C4A1


Antitoxin

Source ID Structure
AlphaFold DB A0A385C6L9

References