109926

Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type II Classification (family/domain) relBE/YoeB-RelB
Location 441056..441566 Replicon chromosome
Accession NZ_CP031716
Organism Acinetobacter wuhouensis strain WCHA60

Toxin (Protein)


Gene name relE Uniprot ID A0A385C064
Locus tag BEN71_RS02715 Protein ID WP_068973744.1
Coordinates 441056..441319 (-) Length 88 a.a.

Antitoxin (Protein)


Gene name relB Uniprot ID A0A385C2H4
Locus tag BEN71_RS02720 Protein ID WP_068973743.1
Coordinates 441303..441566 (-) Length 88 a.a.

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
BEN71_RS02700 436531..437871 - 1341 WP_068973747.1 amidohydrolase -
BEN71_RS02705 438372..439664 + 1293 WP_068973746.1 OprD family outer membrane porin -
BEN71_RS02710 440102..440959 + 858 WP_068973745.1 alpha/beta fold hydrolase -
BEN71_RS02715 441056..441319 - 264 WP_068973744.1 Txe/YoeB family addiction module toxin Toxin
BEN71_RS02720 441303..441566 - 264 WP_068973743.1 type II toxin-antitoxin system prevent-host-death family antitoxin Antitoxin
BEN71_RS02725 441733..442419 - 687 WP_068973742.1 DUF1345 domain-containing protein -
BEN71_RS02730 442707..443612 - 906 WP_068973741.1 DNA-binding transcriptional regulator HcaR -
BEN71_RS02735 443895..445262 + 1368 WP_068973740.1 aromatic ring-hydroxylating dioxygenase subunit alpha -
BEN71_RS02740 445259..445777 + 519 WP_068973739.1 3-phenylpropionate/cinnamic acid dioxygenase subunit beta -
BEN71_RS02745 445777..446103 + 327 WP_068973738.1 bifunctional 3-phenylpropionate/cinnamic acid dioxygenase ferredoxin subunit -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin

Toxin YoeB

(7-86)

Antitoxin

Type II toxin-antitoxin system, antitoxin Phd/YefM

(1-73)


Sequences

Toxin        


Download         Length: 88 a.a.        Molecular weight: 10303.76 Da        Isoelectric Point: 8.4722

>T109926 WP_068973744.1 NZ_CP031716:c441319-441056 [Acinetobacter wuhouensis]
MTRLTSFTPTAWETYIYWQSQDRKTLKRINTLIKECQRTPFEGIGKPEALLGDLSGLWSRRIDEKNRLVYEVTDTAITVI
SCRYHYE

Download         Length: 264 bp

>T109926 NZ_CP031716:c441319-441056 [Acinetobacter wuhouensis]
ATGACACGACTGACTAGTTTCACGCCTACAGCTTGGGAAACTTATATTTATTGGCAAAGCCAAGATAGAAAGACGCTCAA
AAGAATCAATACTTTAATCAAAGAATGTCAACGTACACCCTTTGAAGGTATTGGGAAGCCTGAAGCTTTACTCGGTGATT
TATCTGGATTGTGGAGCAGACGTATAGATGAAAAGAATCGACTGGTCTATGAAGTCACAGATACAGCAATCACCGTAATT
TCCTGCCGTTATCACTATGAATAA

Antitoxin


Download         Length: 88 a.a.        Molecular weight: 9672.88 Da        Isoelectric Point: 5.0474

>AT109926 WP_068973743.1 NZ_CP031716:c441566-441303 [Acinetobacter wuhouensis]
MHVFTYTDARNNLKTVLDKVIDDADVAVITRKEGQHAVVMGQDYYNSIMETLHLLSSPSNAAHLAKSIAELRASKAVERE
LLDDTTD

Download         Length: 264 bp

>AT109926 NZ_CP031716:c441566-441303 [Acinetobacter wuhouensis]
ATGCACGTATTTACATATACAGATGCACGTAACAATCTAAAAACTGTTTTAGATAAAGTGATAGATGATGCCGATGTCGC
TGTAATTACTCGTAAAGAAGGACAACATGCCGTTGTCATGGGACAAGATTATTACAATAGCATTATGGAAACATTACACC
TGTTATCTTCTCCAAGTAATGCTGCCCATTTAGCAAAATCAATTGCTGAATTACGCGCATCGAAAGCAGTCGAAAGAGAA
CTTTTAGATGACACGACTGACTAG

Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure
AlphaFold DB A0A385C064

Antitoxin

Source ID Structure
AlphaFold DB A0A385C2H4

References