109925

Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type II Classification (family/domain) relBE/YafQ-RelB
Location 1596..2163 Replicon plasmid p5_010060
Accession NZ_CP031713
Organism Acinetobacter wuhouensis strain WCHA60

Toxin (Protein)


Gene name relE Uniprot ID A0A385BZ38
Locus tag BEN71_RS00570 Protein ID WP_068975706.1
Coordinates 1596..1877 (-) Length 94 a.a.

Antitoxin (Protein)


Gene name relB Uniprot ID A0A385BZ53
Locus tag BEN71_RS00575 Protein ID WP_068975707.1
Coordinates 1870..2163 (-) Length 98 a.a.

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
BEN71_RS00565 722..1537 - 816 WP_068975705.1 hypothetical protein -
BEN71_RS00570 1596..1877 - 282 WP_068975706.1 type II toxin-antitoxin system YafQ family toxin Toxin
BEN71_RS00575 1870..2163 - 294 WP_068975707.1 type II toxin-antitoxin system RelB/DinJ family antitoxin Antitoxin
BEN71_RS00580 2306..2806 - 501 WP_068975708.1 hypothetical protein -
BEN71_RS00585 2803..3732 - 930 WP_086322811.1 MobA/MobL family protein -
BEN71_RS19165 3732..3887 - 156 WP_167443670.1 hypothetical protein -
BEN71_RS00595 4168..4593 + 426 WP_068975702.1 conjugal transfer protein TraD -
BEN71_RS00600 4631..5056 + 426 WP_068975703.1 hypothetical protein -
BEN71_RS00605 5092..5367 + 276 WP_068975704.1 hypothetical protein -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)
- inside Non-Mobilizable plasmid - - 1..5424 5424


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin

Toxin-antitoxin system, YafQ-like toxin

(4-93)

Antitoxin

RelB antitoxin/Antitoxin DinJ

(1-90)


Sequences

Toxin        


Download         Length: 94 a.a.        Molecular weight: 10707.43 Da        Isoelectric Point: 6.8522

>T109925 WP_068975706.1 NZ_CP031713:c1877-1596 [Acinetobacter wuhouensis]
MAKRKIIVTSSFKRDIKRRYLELVTAEWAEVLDCLVANSPLPEKYLDHPLKGGAEFKNCRDCHVKPDLVLIYRLVGDDVL
ELHQLDSHSEIFG

Download         Length: 282 bp

>T109925 NZ_CP031713:c1877-1596 [Acinetobacter wuhouensis]
ATGGCTAAACGCAAGATCATCGTAACCAGTTCTTTTAAACGTGATATTAAAAGACGTTATTTAGAACTGGTAACGGCTGA
ATGGGCCGAGGTACTGGACTGTTTAGTCGCTAATAGTCCATTGCCTGAAAAATACCTAGATCACCCCTTAAAAGGTGGTG
CTGAGTTTAAAAATTGTCGAGATTGCCACGTTAAACCTGATTTAGTCTTGATTTATAGGCTCGTAGGGGATGATGTTTTA
GAATTACACCAGTTAGATAGCCATTCAGAAATTTTTGGTTAA

Antitoxin


Download         Length: 98 a.a.        Molecular weight: 10971.56 Da        Isoelectric Point: 4.4345

>AT109925 WP_068975707.1 NZ_CP031713:c2163-1870 [Acinetobacter wuhouensis]
MSAVNFNMRLEAELKEKVTPILEDYGLTMPQAFKLFLNQIVKTKTIPLSFDYARETALTPKAAAKLLQSLKEIENGEYTE
YETVEEAIQAMSEEAHG

Download         Length: 294 bp

>AT109925 NZ_CP031713:c2163-1870 [Acinetobacter wuhouensis]
ATGTCCGCAGTCAATTTCAATATGCGTTTAGAGGCAGAACTAAAAGAAAAAGTTACTCCTATTTTGGAGGACTACGGTTT
AACCATGCCACAGGCATTTAAACTGTTCTTGAATCAAATTGTTAAAACGAAAACGATTCCATTGTCTTTTGATTATGCAA
GGGAAACAGCTTTAACCCCTAAAGCAGCAGCAAAGTTGCTTCAATCTCTTAAAGAAATTGAAAATGGGGAGTACACCGAG
TACGAAACAGTAGAAGAAGCCATCCAAGCAATGTCGGAAGAAGCACATGGCTAA

Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure
AlphaFold DB A0A385BZ38

Antitoxin

Source ID Structure
AlphaFold DB A0A385BZ53

References