Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type II Classification (family/domain) yoeB-relB/YoeB-RelB
Location 84..597 Replicon plasmid p4_010060
Accession NZ_CP031712
Organism Acinetobacter wuhouensis strain WCHA60

Toxin (Protein)


Gene name yoeB Uniprot ID N8YGB2
Locus tag BEN71_RS00490 Protein ID WP_000184943.1
Coordinates 84..347 (-) Length 88 a.a.

Antitoxin (Protein)


Gene name relB Uniprot ID N8ZW56
Locus tag BEN71_RS00495 Protein ID WP_000557944.1
Coordinates 334..597 (-) Length 88 a.a.

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
BEN71_RS00490 84..347 - 264 WP_000184943.1 Txe/YoeB family addiction module toxin Toxin
BEN71_RS00495 334..597 - 264 WP_000557944.1 type II toxin-antitoxin system prevent-host-death family antitoxin Antitoxin
BEN71_RS00500 733..1212 - 480 WP_065995571.1 cysteine hydrolase family protein -
BEN71_RS00505 2159..2548 - 390 WP_068975737.1 SgcJ/EcaC family oxidoreductase -
BEN71_RS00510 2930..3217 - 288 WP_000857160.1 hypothetical protein -
BEN71_RS00515 3214..4164 - 951 WP_001031297.1 replication initiation protein -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)
- inside Non-Mobilizable plasmid - - 1..12273 12273


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin

Toxin YoeB

(8-87)

Antitoxin

Type II toxin-antitoxin system, antitoxin Phd/YefM

(1-74)


Sequences

Toxin        


Download         Length: 88 a.a.        Molecular weight: 10649.09 Da        Isoelectric Point: 8.4866

>T109924 WP_000184943.1 NZ_CP031712:c347-84 [Acinetobacter wuhouensis]
MTNRNVEWTDNAWDEYIYWQTQDKKILKRINTLIKECQRTPFEGTGKPEPLKANLSGFWSRRIDEKHRLVYEVTDERISI
IQCRFHY

Download         Length: 264 bp

>T109924 NZ_CP031712:c347-84 [Acinetobacter wuhouensis]
ATGACGAATCGTAACGTCGAATGGACTGATAATGCCTGGGATGAATATATCTATTGGCAGACACAGGATAAAAAGATACT
TAAGCGTATTAATACCTTAATCAAAGAATGTCAGCGAACACCTTTTGAAGGAACAGGAAAACCAGAACCTTTAAAAGCTA
ATCTTTCAGGATTTTGGAGTCGTAGGATTGATGAAAAGCATAGATTAGTTTATGAAGTGACAGATGAACGAATCTCTATA
ATTCAATGTCGATTCCATTACTAA

Antitoxin


Download         Length: 88 a.a.        Molecular weight: 9834.99 Da        Isoelectric Point: 5.0829

>AT109924 WP_000557944.1 NZ_CP031712:c597-334 [Acinetobacter wuhouensis]
MHVFTYTDARNNLKSVLDKVIDDVDVAFITRKEGGHAVVMGQDHYDSLMETLYLLSSPNNASRLNESIAQLRAGKTKHRE
LIEDDES

Download         Length: 264 bp

>AT109924 NZ_CP031712:c597-334 [Acinetobacter wuhouensis]
ATGCATGTATTTACATATACGGACGCACGTAACAATTTAAAATCTGTTTTAGATAAAGTAATTGATGATGTAGACGTTGC
TTTTATTACAAGAAAAGAAGGTGGCCATGCTGTAGTAATGGGACAAGATCATTATGATAGCTTAATGGAAACGTTATATC
TCCTTTCATCTCCAAATAATGCAAGTCGTTTAAATGAATCAATTGCTCAATTACGTGCAGGGAAAACAAAACACAGAGAG
TTGATTGAGGATGACGAATCGTAA

Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure
AlphaFold DB A0A6C0XPS2

Antitoxin

Source ID Structure
AlphaFold DB A0A6C0XPU2

References