Detailed information of TA system
Overview
TA module
| Type | VIII | Classification (family/domain) | SdsR-RyeA/- |
| Location | 2642599..2642833 | Replicon | chromosome |
| Accession | NZ_CP031706 | ||
| Organism | Escherichia coli strain R1 | ||
Toxin (RNA)
| Gene name | SdsR | ||
| Locus tag | - | ||
| Coordinates | 2642600..2642703 (-) |
Antitoxin (RNA)
| Gene name | RyeA | ||
| Locus tag | - | ||
| Coordinates | 2642599..2642833 (+) |
Genomic Context
| Locus tag | Coordinates | Strand | Size (bp) | Protein ID | Product | Description |
|---|---|---|---|---|---|---|
| D0T88_RS12825 | 2638866..2639162 | + | 297 | WP_001484906.1 | host-nuclease inhibitor protein Gam | - |
| D0T88_RS12830 | 2639168..2639953 | + | 786 | WP_001484907.1 | phage recombination protein Bet | - |
| D0T88_RS12835 | 2639950..2640630 | + | 681 | WP_000186708.1 | YqaJ viral recombinase family protein | - |
| D0T88_RS12840 | 2640663..2640857 | + | 195 | WP_001307771.1 | type I toxin-antitoxin system endodeoxyribonuclease toxin RalR | - |
| D0T88_RS12845 | 2640850..2641038 | + | 189 | WP_024165285.1 | DUF1187 family protein | - |
| - | 2640856..2641034 | - | 179 | NuclAT_0 | - | - |
| - | 2640856..2641034 | - | 179 | NuclAT_0 | - | - |
| - | 2640856..2641034 | - | 179 | NuclAT_0 | - | - |
| - | 2640856..2641034 | - | 179 | NuclAT_0 | - | - |
| D0T88_RS12850 | 2641145..2641426 | + | 282 | WP_001311878.1 | excisionase | - |
| D0T88_RS12855 | 2641392..2642468 | + | 1077 | WP_001189085.1 | phage integrase Arm DNA-binding domain-containing protein | - |
| - | 2642599..2642833 | + | 235 | - | - | Antitoxin |
| - | 2642600..2642703 | - | 104 | - | - | Toxin |
| D0T88_RS12860 | 2642861..2643202 | - | 342 | WP_000976492.1 | YebY family protein | - |
| D0T88_RS12865 | 2643215..2644087 | - | 873 | WP_000879280.1 | copper homeostasis membrane protein CopD | - |
| D0T88_RS12870 | 2644091..2644465 | - | 375 | WP_000204699.1 | CopC domain-containing protein YobA | - |
| D0T88_RS12875 | 2644604..2644834 | + | 231 | WP_000916763.1 | DNA polymerase III subunit theta | - |
| D0T88_RS12880 | 2644936..2645592 | + | 657 | WP_000011652.1 | carbon-nitrogen hydrolase family protein | - |
| D0T88_RS12885 | 2645616..2646278 | + | 663 | WP_000944256.1 | exodeoxyribonuclease X | - |
Associated MGEs
| MGE detail |
Similar MGEs |
Relative position |
MGE Type | Cargo ARG | Virulence gene | Coordinates | Length (bp) |
|---|---|---|---|---|---|---|---|
| - | inside | Prophage | - | - | 2585193..2648335 | 63142 |
Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.
Sequences
Toxin
Download Length: 104 bp
>T109900 NZ_CP031706:c2642703-2642600 [Escherichia coli]
GGCAAGGCAACTAAGCCTGCATTAATGCCAACTTTTAGCGCACGGCTCTCTCCCAAGAGCCATTTCCCTGGACCGAATAC
AGGAATCGTATTCGGTCTCTTTTT
GGCAAGGCAACTAAGCCTGCATTAATGCCAACTTTTAGCGCACGGCTCTCTCCCAAGAGCCATTTCCCTGGACCGAATAC
AGGAATCGTATTCGGTCTCTTTTT
Antitoxin
Download Length: 235 bp
>AT109900 NZ_CP031706:2642599-2642833 [Escherichia coli]
TAAAAAGAGACCGAATACGATTCCTGTATTCGGTCCAGGGAAATGGCTCTTGGGAGAGAGCCGTGCGCTAAAAGTTGGCA
TTAATGCAGGCTTAGTTGCCTTGCCCTTTAAGAATAGATGACGACGCCAGGTTTTCCAGTTTGCGTGCAAAATGGTCAAT
AAAAAGCGTGGTGGTCATCAGCTGAAATGTTAAAAACCGCCCGTTCTGGTGAAAGAACTGAGGCGGTTTTTTTAT
TAAAAAGAGACCGAATACGATTCCTGTATTCGGTCCAGGGAAATGGCTCTTGGGAGAGAGCCGTGCGCTAAAAGTTGGCA
TTAATGCAGGCTTAGTTGCCTTGCCCTTTAAGAATAGATGACGACGCCAGGTTTTCCAGTTTGCGTGCAAAATGGTCAAT
AAAAAGCGTGGTGGTCATCAGCTGAAATGTTAAAAACCGCCCGTTCTGGTGAAAGAACTGAGGCGGTTTTTTTAT
