Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type II Classification (family/domain) vapBC/PIN-MazE
Location 350776..351428 Replicon chromosome
Accession NZ_CP031704
Organism Solimonas sp. K1W22B-7

Toxin (Protein)


Gene name vapC Uniprot ID -
Locus tag D0B54_RS01710 Protein ID WP_117288606.1
Coordinates 351006..351428 (+) Length 141 a.a.

Antitoxin (Protein)


Gene name vapB Uniprot ID -
Locus tag D0B54_RS01705 Protein ID WP_117288604.1
Coordinates 350776..351009 (+) Length 78 a.a.

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
D0B54_RS01685 347743..349146 - 1404 WP_117288596.1 efflux RND transporter periplasmic adaptor subunit -
D0B54_RS01690 349326..349943 + 618 WP_117288598.1 TetR/AcrR family transcriptional regulator -
D0B54_RS01695 350109..350351 + 243 WP_117288600.1 CopG family ribbon-helix-helix protein -
D0B54_RS01700 350377..350625 + 249 WP_205527239.1 type II toxin-antitoxin system RelE/ParE family toxin -
D0B54_RS01705 350776..351009 + 234 WP_117288604.1 AbrB/MazE/SpoVT family DNA-binding domain-containing protein Antitoxin
D0B54_RS01710 351006..351428 + 423 WP_117288606.1 PIN domain-containing protein Toxin
D0B54_RS01715 351483..351791 - 309 WP_117288608.1 type II toxin-antitoxin system RelB/DinJ family antitoxin -
D0B54_RS24085 351834..352139 + 306 WP_162932131.1 hypothetical protein -
D0B54_RS01720 352254..352661 + 408 WP_117288610.1 DNA mismatch endonuclease Vsr -
D0B54_RS24090 352627..353397 - 771 WP_162932132.1 hypothetical protein -
D0B54_RS24095 353394..354227 - 834 WP_162932133.1 hypothetical protein -
D0B54_RS01725 354217..356103 - 1887 WP_162932134.1 hypothetical protein -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin

PIN domain

(4-114)

Antitoxin

SpoVT-AbrB domain

(5-34)


Sequences

Toxin        


Download         Length: 141 a.a.        Molecular weight: 15283.60 Da        Isoelectric Point: 4.5502

>T109889 WP_117288606.1 NZ_CP031704:351006-351428 [Solimonas sp. K1W22B-7]
VKPFLDTNILLYAVAQDDPRAEIADALLAAGGIISVQALNEFASVARRKLKMSWDEVHTALDAFQSLCPDPVPLTLETHE
QALQLAQKYGLNLYDALMASAAILAGCPLMYSEDMQDGLELERRLTIRNPFAAGAKPRSL

Download         Length: 423 bp

>T109889 NZ_CP031704:351006-351428 [Solimonas sp. K1W22B-7]
GTGAAACCCTTTCTGGACACCAACATCCTGCTCTACGCCGTGGCGCAGGACGACCCGCGGGCGGAGATCGCAGACGCGCT
GCTCGCGGCAGGCGGGATCATCAGCGTGCAGGCACTGAACGAGTTCGCTTCCGTCGCGCGGCGCAAGCTGAAAATGAGTT
GGGACGAAGTCCACACCGCCCTCGACGCATTCCAGTCCCTCTGCCCAGACCCTGTCCCGCTGACCCTGGAGACGCACGAG
CAGGCGCTGCAGTTGGCCCAGAAGTACGGGCTGAATCTCTACGACGCCCTCATGGCCTCTGCCGCGATACTCGCCGGCTG
CCCGCTGATGTATTCGGAAGACATGCAGGACGGGCTTGAACTCGAGCGCCGCCTCACCATCCGCAACCCGTTCGCCGCTG
GCGCGAAGCCCCGCAGCTTGTAG

Antitoxin


Download         Length: 78 a.a.        Molecular weight: 8906.15 Da        Isoelectric Point: 10.5728

>AT109889 WP_117288604.1 NZ_CP031704:350776-351009 [Solimonas sp. K1W22B-7]
MQVSKWGNSLAVRLPAAVVEALKLQEGDEIEIRIASEREFEVRRDGRKQAALERLRKLRRPLPDGFSFDRDDAQSRK

Download         Length: 234 bp

>AT109889 NZ_CP031704:350776-351009 [Solimonas sp. K1W22B-7]
ATGCAGGTATCCAAGTGGGGCAACAGCCTGGCCGTGCGCCTGCCCGCCGCAGTGGTCGAGGCGCTGAAGCTGCAGGAAGG
CGACGAGATCGAAATCCGCATCGCCTCCGAGCGCGAGTTCGAGGTCCGGCGCGACGGGCGCAAGCAGGCGGCGCTGGAGC
GCCTGCGCAAGCTGCGCCGCCCTCTGCCCGACGGCTTCAGCTTCGACCGTGACGACGCCCAGTCACGCAAGTGA

Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure

Antitoxin

Source ID Structure

References