109885

Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type II Classification (family/domain) EcnAB/-
Location 4023088..4023438 Replicon chromosome
Accession NZ_CP031698
Organism Xanthomonas oryzae pv. oryzae strain PXO142

Toxin (Protein)


Gene name EcnB Uniprot ID G7TLC7
Locus tag DZA55_RS19995 Protein ID WP_011257368.1
Coordinates 4023088..4023222 (-) Length 45 a.a.

Antitoxin (Protein)


Gene name EcnA Uniprot ID G7TLC8
Locus tag DZA55_RS20000 Protein ID WP_011407410.1
Coordinates 4023286..4023438 (-) Length 51 a.a.

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
DZA55_RS19980 (DZA55_19950) 4020105..4021049 - 945 WP_027704118.1 MBL fold metallo-hydrolase -
DZA55_RS19985 (DZA55_19955) 4021180..4022469 - 1290 WP_069959696.1 tryptophan--tRNA ligase -
DZA55_RS19990 (DZA55_19960) 4022638..4022847 - 210 WP_011407411.1 CsbD family protein -
DZA55_RS19995 (DZA55_19965) 4023088..4023222 - 135 WP_011257368.1 entericidin A/B family lipoprotein Toxin
DZA55_RS20000 (DZA55_19970) 4023286..4023438 - 153 WP_011407410.1 entericidin A/B family lipoprotein Antitoxin
DZA55_RS20005 (DZA55_19975) 4023546..4024469 - 924 WP_011407409.1 arginase -
DZA55_RS25540 4024791..4025009 + 219 Protein_3609 hypothetical protein -
DZA55_RS20010 (DZA55_19980) 4025001..4025456 + 456 Protein_3610 hypothetical protein -
DZA55_RS25545 4025453..4025995 + 543 Protein_3611 GTPase -
DZA55_RS20030 (DZA55_20000) 4026475..4027158 + 684 WP_011257363.1 dTMP kinase -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin

Entericidin A/B

(23-42)

Antitoxin

Entericidin A/B

(23-42)


Sequences

Toxin        


Download         Length: 45 a.a.        Molecular weight: 4457.33 Da        Isoelectric Point: 10.2040

>T109885 WP_011257368.1 NZ_CP031698:c4023222-4023088 [Xanthomonas oryzae pv. oryzae]
MKRAIVLLVLSMLSVGLLSGCNTVAGAGKDVKGAGEKVEDAARK

Download         Length: 135 bp

>T109885 NZ_CP031698:c4023222-4023088 [Xanthomonas oryzae pv. oryzae]
ATGAAGCGTGCAATTGTGCTGCTCGTGCTGTCCATGTTGTCGGTCGGTCTGCTGTCGGGCTGCAACACCGTCGCAGGTGC
CGGCAAGGACGTGAAGGGCGCCGGCGAGAAGGTGGAAGACGCAGCGCGTAAGTAA

Antitoxin


Download         Length: 51 a.a.        Molecular weight: 5046.99 Da        Isoelectric Point: 8.7942

>AT109885 WP_011407410.1 NZ_CP031698:c4023438-4023286 [Xanthomonas oryzae pv. oryzae]
MKRLLTLMVLGLFSAGVMTGCNTVAGAGKDLQGAGGKVEKTAEKCSDGKC

Download         Length: 153 bp

>AT109885 NZ_CP031698:c4023438-4023286 [Xanthomonas oryzae pv. oryzae]
ATGAAGCGACTGCTGACACTGATGGTGCTGGGCCTGTTTTCGGCCGGCGTGATGACGGGCTGCAACACCGTGGCTGGCGC
TGGCAAGGACTTGCAGGGCGCGGGTGGGAAGGTCGAGAAAACGGCCGAAAAATGCAGCGATGGTAAGTGCTGA

Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure
AlphaFold DB A0A0C5UG40

Antitoxin

Source ID Structure
AlphaFold DB A0A0C5V759

References