Detailed information of TA system TA109883

Bioinformatically predicted

Overview

TA module

• Type: II
• Classification (family/domain): relB-parE/ParE-RHH
• Location: 1560385..1560941
• Replicon: chromosome
• Accession: NZ_CP031698
• Organism: Xanthomonas oryzae pv. oryzae strain PXO142

Toxin (Protein)

• Gene name: parE
• Uniprot ID: -
• Locus tag: DZA55_RS07775
• Protein ID: WP_229001948.1
• Coordinates: 1560690..1560941 (+)
• Length: 84 a.a.

Antitoxin (Protein)

• Gene name: relB
• Uniprot ID: A0A854CIX2
• Locus tag: DZA55_RS07770
• Protein ID: WP_011408759.1
• Coordinates: 1560385..1560663 (+)
• Length: 93 a.a.

Genomic Context

Locus tag	Coordinates	Strand	Size (bp)	Protein ID	Product	Description
DZA55_RS07740 (DZA55_07740)	1555502..1556059	-	558	WP_011259349.1	DNA-3-methyladenine glycosylase	-
DZA55_RS07745 (DZA55_07745)	1556209..1557174	-	966	WP_109181928.1	IS1595-like element ISXo5 family transposase	-
DZA55_RS07755 (DZA55_07755)	1557755..1558939	+	1185	WP_011408760.1	IS256-like element IS1113 family transposase	-
DZA55_RS07765 (DZA55_07765)	1559803..1560189	+	387	WP_205412094.1	hypothetical protein	-
DZA55_RS07770 (DZA55_07770)	1560385..1560663	+	279	WP_011408759.1	CopG family ribbon-helix-helix protein	Antitoxin
DZA55_RS07775 (DZA55_07775)	1560690..1560941	+	252	WP_229001948.1	type II toxin-antitoxin system RelE/ParE family toxin	Toxin
DZA55_RS25215	1561202..1561399	+	198	WP_004541336.1	hypothetical protein	-
DZA55_RS07785 (DZA55_07785)	1561468..1561722	+	255	WP_223293127.1	hypothetical protein	-
DZA55_RS25220 (DZA55_07790)	1561939..1562058	+	120	Protein_1393	IS3 family transposase	-
DZA55_RS25700	1562027..1562155	+	129	WP_012444694.1	hypothetical protein	-
DZA55_RS07805 (DZA55_07805)	1562586..1562987	-	402	WP_011259345.1	H-NS family nucleoid-associated regulatory protein	-
DZA55_RS07810 (DZA55_07810)	1563209..1563385	+	177	Protein_1396	DUF3606 domain-containing protein	-
DZA55_RS07820 (DZA55_07820)	1563667..1564004	+	338	Protein_1397	ATP-dependent DNA ligase	-
DZA55_RS07825 (DZA55_07825)	1564080..1565171	-	1092	WP_041182166.1	ribonuclease D	-

Associated MGEs

MGE detail	Similar MGEs	Relative position	MGE Type	Cargo ARG	Virulence gene	Coordinates	Length (bp)

Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.

Domains

Predicted by InterproScan

Toxin

• Toxin-antitoxin system, RelE/ParE toxin family (3-81)

Antitoxin

• Ribbon-helix-helix protein, CopG (5-42)

Sequences

Toxin

Protein

• Length: 84 a.a.
• Molecular weight: 9603.92 Da
• Isoelectric Point: 9.9718

>T109883 WP_229001948.1 NZ_CP031698:1560690-1560941 [Xanthomonas oryzae pv. oryzae]
MLRLREFLRPKNPDAARRAGEAIRRGVQALGAHPRMGRLIEDLSEQYREWLIDFGDSGYVARYRFDGDTVTILAVRHQKE
AGY

Nucleotide

• Length: 252 bp

>T109883 NZ_CP031698:1560690-1560941 [Xanthomonas oryzae pv. oryzae]
ATGCTACGGCTGCGTGAATTCCTGAGGCCGAAGAATCCCGATGCCGCGAGGCGGGCCGGCGAAGCGATTAGGCGCGGCGT
CCAGGCTCTCGGTGCCCACCCTCGAATGGGGCGGCTCATAGAAGATCTGTCTGAACAGTATCGGGAGTGGCTTATCGATT
TTGGGGATAGCGGCTATGTGGCTCGGTACCGCTTCGATGGGGATACCGTCACGATTTTGGCCGTGCGACACCAGAAGGAA
GCGGGGTACTGA

Antitoxin

Protein

• Length: 93 a.a.
• Molecular weight: 10826.11 Da
• Isoelectric Point: 4.9736

>AT109883 WP_011408759.1 NZ_CP031698:1560385-1560663 [Xanthomonas oryzae pv. oryzae]
MVTATSIKLDDELKGRVQHLAESRRRTPHWIMREAIEQYVEREEKREALNRDTLKAWDEFQATGLHVTAEEVDKWLASWG
TDDELPPPECHK

Nucleotide

• Length: 279 bp

>AT109883 NZ_CP031698:1560385-1560663 [Xanthomonas oryzae pv. oryzae]
ATGGTTACGGCAACTTCCATCAAGCTTGATGATGAATTGAAAGGGCGGGTTCAGCACTTGGCAGAGTCGCGCCGGCGTAC
CCCGCATTGGATCATGCGCGAAGCCATTGAGCAGTACGTCGAGCGCGAGGAAAAGCGCGAGGCGCTGAACCGGGACACGC
TCAAGGCATGGGATGAATTTCAGGCGACTGGCCTGCATGTGACCGCTGAGGAAGTGGACAAGTGGCTCGCTAGCTGGGGA
ACTGACGACGAACTGCCTCCGCCAGAATGCCACAAGTAA

Structures

Antitoxin

• AlphaFold DB: A0A854CIX2