109881

Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type II Classification (family/domain) EcnAB/-
Location 4702017..4702367 Replicon chromosome
Accession NZ_CP031697
Organism Xanthomonas oryzae pv. oryzae strain ICMP3125

Toxin (Protein)


Gene name EcnB Uniprot ID G7TLC7
Locus tag DZA53_RS23110 Protein ID WP_011257368.1
Coordinates 4702017..4702151 (-) Length 45 a.a.

Antitoxin (Protein)


Gene name EcnA Uniprot ID G7TLC8
Locus tag DZA53_RS23115 Protein ID WP_011407410.1
Coordinates 4702215..4702367 (-) Length 51 a.a.

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
DZA53_RS23095 4699031..4700053 - 1023 WP_075240574.1 MBL fold metallo-hydrolase -
DZA53_RS23100 4700106..4701395 - 1290 WP_011257370.1 tryptophan--tRNA ligase -
DZA53_RS23105 4701564..4701773 - 210 WP_011407411.1 CsbD family protein -
DZA53_RS23110 4702017..4702151 - 135 WP_011257368.1 entericidin A/B family lipoprotein Toxin
DZA53_RS23115 4702215..4702367 - 153 WP_011407410.1 entericidin A/B family lipoprotein Antitoxin
DZA53_RS23120 4702475..4703398 - 924 WP_011407409.1 arginase -
DZA53_RS23125 4703720..4704394 + 675 WP_011257366.1 hypothetical protein -
DZA53_RS23130 4704391..4704630 + 240 WP_011257365.1 hypothetical protein -
DZA53_RS23135 4704637..4704933 + 297 WP_012446308.1 hypothetical protein -
DZA53_RS23145 4705413..4706096 + 684 WP_011257363.1 dTMP kinase -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin

Entericidin A/B

(23-42)

Antitoxin

Entericidin A/B

(23-42)


Sequences

Toxin        


Download         Length: 45 a.a.        Molecular weight: 4457.33 Da        Isoelectric Point: 10.2040

>T109881 WP_011257368.1 NZ_CP031697:c4702151-4702017 [Xanthomonas oryzae pv. oryzae]
MKRAIVLLVLSMLSVGLLSGCNTVAGAGKDVKGAGEKVEDAARK

Download         Length: 135 bp

>T109881 NZ_CP031697:c4702151-4702017 [Xanthomonas oryzae pv. oryzae]
ATGAAGCGTGCAATTGTGCTGCTCGTGCTGTCCATGTTGTCGGTCGGTCTGCTGTCGGGCTGCAACACCGTCGCAGGTGC
CGGCAAGGACGTGAAGGGCGCCGGCGAGAAGGTGGAAGACGCAGCGCGTAAGTAA

Antitoxin


Download         Length: 51 a.a.        Molecular weight: 5046.99 Da        Isoelectric Point: 8.7942

>AT109881 WP_011407410.1 NZ_CP031697:c4702367-4702215 [Xanthomonas oryzae pv. oryzae]
MKRLLTLMVLGLFSAGVMTGCNTVAGAGKDLQGAGGKVEKTAEKCSDGKC

Download         Length: 153 bp

>AT109881 NZ_CP031697:c4702367-4702215 [Xanthomonas oryzae pv. oryzae]
ATGAAGCGACTGCTGACACTGATGGTGCTGGGCCTGTTTTCGGCCGGCGTGATGACGGGCTGCAACACCGTGGCTGGCGC
TGGCAAGGACTTGCAGGGCGCGGGTGGGAAGGTCGAGAAAACGGCCGAAAAATGCAGCGATGGTAAGTGCTGA

Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure
AlphaFold DB A0A0C5UG40

Antitoxin

Source ID Structure
AlphaFold DB A0A0C5V759

References