Detailed information of TA system TA109880

Bioinformatically predicted

Overview

TA module

• Type: II
• Classification (family/domain): relB-parE/ParE-RHH
• Location: 3254445..3255001
• Replicon: chromosome
• Accession: NZ_CP031697
• Organism: Xanthomonas oryzae pv. oryzae strain ICMP3125

Toxin (Protein)

• Gene name: parE
• Uniprot ID: -
• Locus tag: DZA53_RS15960
• Protein ID: WP_027703932.1
• Coordinates: 3254445..3254735 (-)
• Length: 97 a.a.

Antitoxin (Protein)

• Gene name: relB
• Uniprot ID: A0A854CIX2
• Locus tag: DZA53_RS15965
• Protein ID: WP_011408759.1
• Coordinates: 3254723..3255001 (-)
• Length: 93 a.a.

Genomic Context

Locus tag	Coordinates	Strand	Size (bp)	Protein ID	Product	Description
DZA53_RS15910	3250215..3251306	+	1092	WP_011408756.1	ribonuclease D	-
DZA53_RS15915	3251403..3251719	-	317	Protein_2877	ATP-dependent DNA ligase	-
DZA53_RS24825	3251779..3251985	-	207	Protein_2878	hypothetical protein	-
DZA53_RS15925	3252001..3252177	-	177	Protein_2879	DUF3606 domain-containing protein	-
DZA53_RS15930	3252399..3252800	+	402	WP_027703933.1	H-NS histone family protein	-
DZA53_RS15950	3253664..3253843	-	180	WP_015463309.1	hypothetical protein	-
DZA53_RS24830	3253987..3254184	-	198	WP_153296741.1	hypothetical protein	-
DZA53_RS15960	3254445..3254735	-	291	WP_027703932.1	type II toxin-antitoxin system RelE/ParE family toxin	Toxin
DZA53_RS15965	3254723..3255001	-	279	WP_011408759.1	CopG family ribbon-helix-helix protein	Antitoxin
DZA53_RS25105	3255082..3255285	-	204	WP_198912807.1	hypothetical protein	-
DZA53_RS25110	3255197..3255541	-	345	WP_198912817.1	hypothetical protein	-
DZA53_RS15975	3255486..3255686	-	201	WP_027703931.1	ribbon-helix-helix protein, CopG family	-
DZA53_RS15980	3256447..3257631	-	1185	WP_011408397.1	IS256 family transposase	-
DZA53_RS15990	3258212..3259177	+	966	WP_109181928.1	IS1595-like element ISXo5 family transposase	-
DZA53_RS15995	3259279..3259884	+	606	Protein_2890	DNA-3-methyladenine glycosylase	-

Associated MGEs

MGE detail	Similar MGEs	Relative position	MGE Type	Cargo ARG	Virulence gene	Coordinates	Length (bp)

Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.

Domains

Predicted by InterproScan

Toxin

• Toxin-antitoxin system, RelE/ParE toxin family (4-94)

Antitoxin

• Ribbon-helix-helix protein, CopG (5-42)

Sequences

Toxin

Protein

• Length: 97 a.a.
• Molecular weight: 10915.48 Da
• Isoelectric Point: 9.5554

>T109880 WP_027703932.1 NZ_CP031697:c3254735-3254445 [Xanthomonas oryzae pv. oryzae]
MPQVIFAPAAIGDMLRLREFLRPKNPDAARRAGEAIRRGVQALGAHPRMGRLIEDLSEQYREWLIDFGDSGYVARYRFDG
DTVTILAVRHQKEAGY

Nucleotide

• Length: 291 bp

>T109880 NZ_CP031697:c3254735-3254445 [Xanthomonas oryzae pv. oryzae]
ATGCCACAAGTAATCTTTGCGCCGGCGGCGATCGGGGACATGCTACGGCTGCGTGAATTCCTGAGGCCGAAGAATCCCGA
TGCCGCGAGGCGGGCCGGCGAAGCGATTAGGCGCGGCGTCCAGGCTCTCGGTGCCCACCCTCGAATGGGGCGGCTCATAG
AAGATCTGTCTGAACAGTATCGGGAGTGGCTTATCGATTTTGGGGATAGCGGCTATGTGGCTCGGTACCGCTTCGATGGG
GATACCGTCACGATTTTGGCCGTGCGACACCAGAAGGAAGCGGGGTACTGA

Antitoxin

Protein

• Length: 93 a.a.
• Molecular weight: 10826.11 Da
• Isoelectric Point: 4.9736

>AT109880 WP_011408759.1 NZ_CP031697:c3255001-3254723 [Xanthomonas oryzae pv. oryzae]
MVTATSIKLDDELKGRVQHLAESRRRTPHWIMREAIEQYVEREEKREALNRDTLKAWDEFQATGLHVTAEEVDKWLASWG
TDDELPPPECHK

Nucleotide

• Length: 279 bp

>AT109880 NZ_CP031697:c3255001-3254723 [Xanthomonas oryzae pv. oryzae]
ATGGTTACGGCAACTTCCATCAAGCTTGATGATGAATTGAAAGGGCGGGTTCAGCACTTGGCAGAGTCGCGCCGGCGTAC
CCCGCATTGGATCATGCGCGAAGCCATTGAGCAGTACGTCGAGCGCGAGGAAAAGCGCGAGGCGCTGAACCGGGACACGC
TCAAGGCATGGGATGAATTTCAGGCGACTGGCCTGCATGTGACCGCTGAGGAAGTGGACAAGTGGCTCGCGAGCTGGGGA
ACTGACGACGAACTGCCTCCGCCAGAATGCCACAAGTAA

Structures

Antitoxin

• AlphaFold DB: A0A854CIX2