Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type II Classification (family/domain) rlegTA/AbiEii-AbiEi
Location 1955953..1957472 Replicon chromosome
Accession NZ_CP031697
Organism Xanthomonas oryzae pv. oryzae strain ICMP3125

Toxin (Protein)


Gene name rlegT Uniprot ID A0A0K0GMB6
Locus tag DZA53_RS09745 Protein ID WP_011259680.1
Coordinates 1956549..1957472 (+) Length 308 a.a.

Antitoxin (Protein)


Gene name rlegA Uniprot ID A0A0K0GMG7
Locus tag DZA53_RS09740 Protein ID WP_012445456.1
Coordinates 1955953..1956552 (+) Length 200 a.a.

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
DZA53_RS09700 1951836..1952054 - 219 Protein_1748 DUF1788 domain-containing protein -
DZA53_RS09705 1952035..1952774 - 740 Protein_1749 DUF1819 family protein -
DZA53_RS09710 1952824..1953850 + 1027 WP_099051289.1 IS630 family transposase -
DZA53_RS09720 1953993..1954791 + 799 WP_094187763.1 IS5 family transposase -
DZA53_RS09725 1954778..1955266 - 489 WP_027703988.1 BrxE family protein -
DZA53_RS09730 1955298..1955618 - 321 WP_027703987.1 hypothetical protein -
DZA53_RS09740 1955953..1956552 + 600 WP_012445456.1 AbiEi antitoxin N-terminal domain-containing protein Antitoxin
DZA53_RS09745 1956549..1957472 + 924 WP_011259680.1 nucleotidyl transferase AbiEii/AbiGii toxin family protein Toxin
DZA53_RS09750 1957552..1957800 - 249 WP_033013473.1 hypothetical protein -
DZA53_RS09755 1957834..1958055 - 222 Protein_1757 hypothetical protein -
DZA53_RS09760 1958488..1958730 + 243 WP_011259679.1 hypothetical protein -
DZA53_RS09765 1959155..1959664 + 510 WP_011259678.1 hypothetical protein -
DZA53_RS09770 1959681..1960213 - 533 Protein_1760 methyltransferase domain-containing protein -
DZA53_RS09775 1960233..1961609 - 1377 Protein_1761 IS5 family transposase -
DZA53_RS09780 1961721..1961873 - 153 Protein_1762 SAM-dependent methyltransferase -
DZA53_RS25035 1962008..1962229 + 222 WP_154215184.1 hypothetical protein -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin

Nucleotidyl transferase AbiEii toxin, Type IV TA system

(41-269)

Antitoxin

Transcriptional regulator, AbiEi antitoxin

(7-52)


Sequences

Toxin        


Download         Length: 308 a.a.        Molecular weight: 34114.16 Da        Isoelectric Point: 5.4588

>T109879 WP_011259680.1 NZ_CP031697:1956549-1957472 [Xanthomonas oryzae pv. oryzae]
MNEPDKSRRTVAASVRARLLNKARAERLDFNLLLTRYALERVLYRLSVSEQQGQFLLKGALLFDIWFDIPHRPTHDADLL
GFGSTEIPHLEDLFRRISQIASDDGIVFQADSVKAAEIRKEANYAGVRVTMIGLLDGARCTVQIDIGFGDAVTPGPDNVQ
YPVILDGMPQPQLRVYPRYTVVAEKLEAMVKLGILNSRMKDYFDLWVLAGHSDFDGAVLATAIRATFECRGTAIPPGAPL
GLTDEFGLDEQKTKQWQAFLRKNTLEPMPLTTVIEALREFVLPVLAALAAGEGFDRQWRAGAGWDAA

Download         Length: 924 bp

>T109879 NZ_CP031697:1956549-1957472 [Xanthomonas oryzae pv. oryzae]
ATGAACGAACCTGACAAGAGCAGGCGCACTGTTGCCGCGTCGGTTCGCGCCCGGCTGCTCAACAAGGCCCGCGCCGAAAG
ACTCGACTTCAACCTGCTGCTGACCCGCTACGCGCTGGAGCGCGTCCTTTACCGCCTGAGCGTTTCGGAGCAGCAGGGTC
AATTCTTGCTCAAAGGTGCGCTGCTGTTCGACATCTGGTTCGACATACCGCATCGCCCGACGCACGATGCCGACCTGCTG
GGCTTCGGCTCCACCGAGATCCCACATCTGGAAGACCTGTTCCGCAGAATCAGTCAAATCGCCAGCGATGACGGCATCGT
GTTTCAGGCCGACAGCGTGAAGGCCGCCGAAATCCGCAAGGAGGCCAACTACGCGGGCGTCCGTGTGACGATGATCGGCC
TGCTCGATGGCGCGCGCTGCACGGTGCAGATCGACATCGGTTTCGGCGACGCCGTGACGCCCGGCCCGGACAACGTGCAG
TACCCAGTCATCCTCGACGGCATGCCGCAGCCGCAACTGCGGGTCTATCCCCGCTACACCGTGGTCGCCGAAAAGCTGGA
AGCGATGGTCAAGCTCGGCATCCTCAACAGCCGGATGAAGGACTACTTCGACCTCTGGGTTCTCGCCGGACATTCCGACT
TCGACGGTGCGGTGCTGGCCACGGCCATTCGCGCCACGTTCGAGTGCAGGGGTACGGCCATCCCACCCGGCGCGCCGCTG
GGCCTCACCGATGAGTTCGGCCTGGACGAGCAGAAGACAAAGCAGTGGCAGGCGTTCCTGCGCAAGAACACCTTGGAGCC
GATGCCGCTGACCACGGTGATCGAAGCGCTGCGCGAATTCGTGCTGCCCGTGCTGGCCGCGCTCGCGGCAGGCGAAGGTT
TCGACCGCCAGTGGCGCGCGGGCGCGGGATGGGATGCGGCCTGA

Antitoxin


Download         Length: 200 a.a.        Molecular weight: 22051.76 Da        Isoelectric Point: 10.1240

>AT109879 WP_012445456.1 NZ_CP031697:1955953-1956552 [Xanthomonas oryzae pv. oryzae]
MDTTIDKLLELVRTRGLLRPHDLAPLGIPRVALTRAVRRGQLERVGRGLYGLVARPVSAHGTLAEVARRVPKGVVCLLSA
LRVHDLTTQAPFEVWLAIDNKAAAPKLDYPPLRLVRFSGPALSEGVEEHVVDGVPVHVTSVAKTVADCFKYRNKIGIDVA
LEALREAWVARRMTSDEIWHYAKIDRVANVMRPYLESLA

Download         Length: 600 bp

>AT109879 NZ_CP031697:1955953-1956552 [Xanthomonas oryzae pv. oryzae]
ATGGACACGACCATCGACAAGCTGCTGGAGCTGGTGCGTACGCGGGGACTTCTGCGCCCGCACGATCTGGCCCCACTGGG
CATCCCACGGGTGGCCCTGACGCGGGCCGTTCGGCGCGGGCAACTGGAGCGCGTCGGGCGCGGCCTGTACGGCCTGGTGG
CGCGTCCGGTGTCGGCCCACGGCACGCTGGCCGAAGTCGCGCGCCGCGTGCCCAAGGGCGTGGTCTGCCTGCTGTCGGCG
CTGCGCGTCCACGACCTGACGACCCAGGCCCCGTTCGAGGTGTGGCTGGCCATCGACAACAAGGCCGCTGCCCCGAAGCT
GGACTACCCGCCGCTACGTCTCGTGCGCTTCTCCGGGCCGGCGCTGAGCGAGGGCGTCGAGGAACACGTTGTCGATGGTG
TGCCCGTCCACGTGACCAGCGTCGCCAAGACCGTGGCCGACTGCTTCAAGTACCGCAACAAGATCGGCATCGACGTGGCG
CTGGAAGCGCTGCGCGAGGCGTGGGTTGCCCGGCGCATGACCAGCGACGAGATCTGGCACTACGCCAAGATCGACCGCGT
CGCCAACGTGATGCGTCCCTATCTGGAGAGCCTGGCATGA

Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure
AlphaFold DB A0A0K0GMB6

Antitoxin

Source ID Structure
AlphaFold DB A0A0K0GMG7

References