109855

Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type II Classification (family/domain) relBE/ParE-DnaT
Location 74752..75286 Replicon chromosome
Accession NZ_CP031692
Organism Haemophilus influenzae strain P595-8370

Toxin (Protein)


Gene name relE Uniprot ID -
Locus tag CH556_RS00380 Protein ID WP_116945019.1
Coordinates 74996..75286 (+) Length 97 a.a.

Antitoxin (Protein)


Gene name relB Uniprot ID -
Locus tag CH556_RS00375 Protein ID WP_116945020.1
Coordinates 74752..75006 (+) Length 85 a.a.

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
CH556_RS00345 70344..70604 + 261 WP_005669564.1 hypothetical protein -
CH556_RS00350 70635..71000 + 366 WP_005669560.1 endonuclease domain-containing protein -
CH556_RS00355 71338..73404 + 2067 WP_116945022.1 glycine--tRNA ligase subunit beta -
CH556_RS00365 73922..74230 + 309 WP_116945021.1 P2 family phage major capsid protein -
CH556_RS09210 74230..74454 + 225 Protein_70 hypothetical protein -
CH556_RS00375 74752..75006 + 255 WP_116945020.1 stability protein StbD Antitoxin
CH556_RS00380 74996..75286 + 291 WP_116945019.1 type II toxin-antitoxin system RelE/ParE family toxin Toxin
CH556_RS00385 75367..75552 + 186 WP_116945206.1 hypothetical protein -
CH556_RS09175 75722..75859 + 138 WP_162877091.1 hypothetical protein -
CH556_RS00390 76202..77236 - 1035 WP_116945018.1 DNA polymerase III subunit delta -
CH556_RS00395 77236..77739 - 504 WP_005651506.1 hypothetical protein -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin

Toxin-antitoxin system, RelE/ParE toxin family

(5-83)

Antitoxin


No domain identified.



Sequences

Toxin        


Download         Length: 97 a.a.        Molecular weight: 11512.44 Da        Isoelectric Point: 10.6484

>T109855 WP_116945019.1 NZ_CP031692:74996-75286 [Haemophilus influenzae]
MTYKLIFDKRALKEWNKLGETLRQQFKNKLAERMINPRIQADKLKGENDLYKIKLRSTGYRLVYQVRDQEITIIVVSVGK
RERLEVYKTAEQRTAH

Download         Length: 291 bp

>T109855 NZ_CP031692:74996-75286 [Haemophilus influenzae]
ATGACTTATAAACTCATTTTTGATAAACGCGCATTAAAAGAATGGAATAAATTGGGGGAAACCTTACGCCAACAATTTAA
AAATAAATTAGCCGAAAGAATGATAAATCCACGCATTCAAGCCGACAAATTAAAGGGCGAAAATGATTTATATAAAATCA
AATTAAGAAGCACTGGTTATCGATTAGTTTATCAAGTAAGAGATCAGGAAATCACCATTATTGTTGTATCTGTTGGAAAA
AGGGAACGATTAGAAGTCTATAAAACCGCAGAACAAAGAACAGCCCACTAA

Antitoxin


Download         Length: 85 a.a.        Molecular weight: 9435.78 Da        Isoelectric Point: 4.0737

>AT109855 WP_116945020.1 NZ_CP031692:74752-75006 [Haemophilus influenzae]
MALHQILAEQAASITDLKRNPMGVIQESESGIVAILNRNQPAFYCITPELFSHMQELIEDLELGRMANERLSTLEPVEVD
LNDL

Download         Length: 255 bp

>AT109855 NZ_CP031692:74752-75006 [Haemophilus influenzae]
ATGGCATTACATCAAATACTGGCAGAACAAGCGGCAAGCATTACAGACTTAAAACGAAACCCAATGGGCGTAATTCAAGA
AAGCGAAAGCGGAATAGTCGCAATATTGAACCGAAACCAACCCGCATTTTATTGCATCACCCCCGAATTATTCTCTCATA
TGCAAGAATTAATCGAAGATTTAGAGCTCGGCAGAATGGCAAATGAACGGCTATCCACCCTAGAACCAGTAGAGGTTGAT
CTAAATGACTTATAA

Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure

Antitoxin

Source ID Structure

References