Detailed information of TA system    

insolicoBioinformatically predicted

Overview


TA module


Type VIII Classification (family/domain) SdsR-RyeA/-
Location 2134082..2134353 Replicon chromosome
Accession NZ_CP031653
Organism Escherichia coli strain UK_Dog_Liverpool

Toxin (RNA)


Gene name SdsR
Locus tag -
Coordinates 2134212..2134315 (+)

Antitoxin (RNA)


Gene name RyeA
Locus tag -
Coordinates 2134082..2134353 (-)

Genomic Context


Locus tag Coordinates Strand Size (bp) Protein ID Product Description
DL545_RS11045 2130637..2131299 - 663 WP_000944256.1 exodeoxyribonuclease X -
DL545_RS11050 2131323..2131979 - 657 WP_000011658.1 carbon-nitrogen hydrolase family protein -
DL545_RS11055 2132081..2132311 - 231 WP_000916763.1 DNA polymerase III subunit theta -
DL545_RS11060 2132450..2132824 + 375 WP_000204699.1 CopC domain-containing protein YobA -
DL545_RS11065 2132828..2133700 + 873 WP_000879280.1 copper homeostasis membrane protein CopD -
DL545_RS11070 2133713..2134054 + 342 WP_000976492.1 YebY family protein -
- 2134082..2134353 - 272 - - Antitoxin
- 2134212..2134315 + 104 - - Toxin
DL545_RS11075 2134450..2135106 + 657 WP_000812724.1 protein-serine/threonine phosphatase -
DL545_RS11080 2135107..2135298 - 192 WP_001296140.1 YebW family protein -
DL545_RS11085 2135403..2135639 - 237 WP_001295499.1 DUF1480 family protein -
DL545_RS11090 2135757..2137196 - 1440 WP_000057023.1 16S rRNA (cytosine(1407)-C(5))-methyltransferase RsmF -

Associated MGEs


MGE
detail
Similar
MGEs
Relative
position
MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Sequences


Toxin        


Download         Length: 104 bp

>T109631 NZ_CP031653:2134212-2134315 [Escherichia coli]
GGCAAGGCAACTAAGCCTGCATTAATGCCAACTTTTAGCGCACGGCTCTCTCCCAAGAGCCATTTCCCTGGACCGAATAC
AGGAATCGTGTTCGGTCTCTTTTT

Antitoxin


Download         Length: 272 bp

>AT109631 NZ_CP031653:c2134353-2134082 [Escherichia coli]
AAAGTCAGCGAAGGAAATGCTTCTGGCTTTTAACAGATAAAAAGAGACCGAACACGATTCCTGTATTCGGTCCAGGGAAA
TGGCTCTTGGGAGAGAGCCGTGCGCTAAAAGTTGGCATTAATGCAGGCTTAGTTGCCTTGCCCTTTAAGAATAGATGACG
ACGCCAGGTTTTCCAGTTTGCGTGCAAAATGGTCAATAAAAAGCGTGGTGGTCATCAGCTGAAATGTTAAAAACCGCCCG
TTCTGGTGAAAGAACTGAGGCGGTTTTTTTAT

Structures


Antitoxin

Download structure file

Antitoxin

Download structure file

References