Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type II Classification (family/domain) relBE/ParE-YafN
Location 66492..67027 Replicon plasmid unnamed2
Accession NZ_CP031651
Organism Pantoea agglomerans strain TH81

Toxin (Protein)


Gene name relE Uniprot ID -
Locus tag D0A61_RS22160 Protein ID WP_122459971.1
Coordinates 66740..67027 (+) Length 96 a.a.

Antitoxin (Protein)


Gene name relB Uniprot ID -
Locus tag D0A61_RS22155 Protein ID WP_122459970.1
Coordinates 66492..66743 (+) Length 84 a.a.

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
D0A61_RS22135 62095..62364 - 270 WP_010257103.1 DUF1471 domain-containing protein -
D0A61_RS22140 62640..63776 - 1137 WP_122459968.1 HlyD family secretion protein -
D0A61_RS22145 63778..64104 - 327 WP_010257107.1 DUF3302 domain-containing protein -
D0A61_RS22150 64699..66351 + 1653 WP_122459969.1 intermembrane transport protein PqiB -
D0A61_RS22155 66492..66743 + 252 WP_122459970.1 type II toxin-antitoxin system Phd/YefM family antitoxin Antitoxin
D0A61_RS22160 66740..67027 + 288 WP_122459971.1 type II toxin-antitoxin system RelE/ParE family toxin Toxin
D0A61_RS22165 67390..67704 + 315 WP_122459972.1 hypothetical protein -
D0A61_RS22170 67701..68519 - 819 WP_069027206.1 DUF4225 domain-containing protein -
D0A61_RS22175 68778..69008 + 231 Protein_60 helix-turn-helix domain-containing protein -
D0A61_RS22180 69028..69665 + 638 Protein_61 transposase -
D0A61_RS22190 70224..71819 + 1596 WP_122459974.1 GNAT family N-acetyltransferase -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)
- inside Mobilizable plasmid - - 1..182169 182169
- flank IS/Tn - - 69049..69492 443


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin

Toxin-antitoxin system, RelE/ParE toxin family

(5-83)

Antitoxin


No domain identified.



Sequences

Toxin        


Download         Length: 96 a.a.        Molecular weight: 11174.03 Da        Isoelectric Point: 10.1343

>T109613 WP_122459971.1 NZ_CP031651:66740-67027 [Pantoea agglomerans]
VSYTVKFREEAFKEWQKLDKSLQQQFAKKLKECCDNPHIPSARLRGIKDCYKIKLRASGFRLVYQVIDDQLVIAVVAVGK
RERSDVYHLASERMR

Download         Length: 288 bp

>T109613 NZ_CP031651:66740-67027 [Pantoea agglomerans]
GTGAGTTATACCGTCAAATTCAGGGAAGAGGCATTTAAAGAATGGCAGAAGCTGGACAAATCTCTCCAGCAGCAGTTTGC
CAAAAAACTGAAGGAATGTTGTGACAATCCCCATATTCCTTCTGCCAGACTACGAGGGATTAAAGACTGCTATAAAATCA
AACTCAGAGCGTCCGGGTTTCGCCTGGTTTATCAGGTAATAGACGATCAACTGGTGATTGCCGTTGTTGCTGTGGGTAAA
CGCGAGCGCAGCGATGTTTATCATCTTGCCAGTGAAAGGATGCGGTAG

Antitoxin


Download         Length: 84 a.a.        Molecular weight: 9147.45 Da        Isoelectric Point: 3.9507

>AT109613 WP_122459970.1 NZ_CP031651:66492-66743 [Pantoea agglomerans]
MPNIILSDTSASVSELKKNPMATVNAGDGYPVAILNRNQPAFYCVPAELYEQMLDALDDQELVKLVNERSKQPLIDVDLD
ALL

Download         Length: 252 bp

>AT109613 NZ_CP031651:66492-66743 [Pantoea agglomerans]
ATGCCAAACATTATTTTAAGCGATACCAGTGCCAGCGTAAGCGAACTGAAGAAAAATCCGATGGCCACGGTTAATGCAGG
TGACGGTTATCCTGTCGCCATTCTTAACCGCAACCAGCCTGCATTCTATTGCGTCCCGGCTGAGCTTTATGAACAAATGC
TTGATGCCCTTGACGATCAGGAACTGGTTAAGCTGGTCAATGAACGTAGCAAACAGCCGTTAATTGATGTCGATTTGGAT
GCGCTTTTGTGA

Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure

Antitoxin

Source ID Structure

References