Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type II Classification (family/domain) PumA-relB/upstrm_HI1419-dnstrm_HI1420
Location 6297865..6298461 Replicon chromosome
Accession NZ_CP031648
Organism Pseudomonas fluorescens strain Pf275

Toxin (Protein)


Gene name PumA Uniprot ID -
Locus tag DZG01_RS29190 Protein ID WP_109752224.1
Coordinates 6298159..6298461 (-) Length 101 a.a.

Antitoxin (Protein)


Gene name relB Uniprot ID -
Locus tag DZG01_RS29185 Protein ID WP_109752223.1
Coordinates 6297865..6298155 (-) Length 97 a.a.

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
DZG01_RS29165 6294108..6296234 - 2127 WP_116834071.1 TonB-dependent copper receptor -
DZG01_RS29170 6296319..6296723 - 405 WP_116834072.1 DUF2946 domain-containing protein -
DZG01_RS29175 6296781..6297260 - 480 WP_109752221.1 copper chaperone PCu(A)C -
DZG01_RS29180 6297308..6297706 - 399 WP_116834073.1 DUF2946 domain-containing protein -
DZG01_RS29185 6297865..6298155 - 291 WP_109752223.1 putative addiction module antidote protein Antitoxin
DZG01_RS29190 6298159..6298461 - 303 WP_109752224.1 type II toxin-antitoxin system RelE/ParE family toxin Toxin
DZG01_RS29195 6298654..6299382 - 729 WP_116834074.1 cobalt-precorrin-6A reductase -
DZG01_RS29200 6299379..6300476 - 1098 WP_116834075.1 cobalt-precorrin-5B (C(1))-methyltransferase -
DZG01_RS29205 6300469..6301680 - 1212 WP_116834076.1 precorrin-6y C5,15-methyltransferase (decarboxylating) subunit CbiE -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin

Addiction module killer protein, predicted

(1-96)

Antitoxin

Uncharacterized protein HI1420

(5-94)


Sequences

Toxin        


Download         Length: 101 a.a.        Molecular weight: 11268.84 Da        Isoelectric Point: 9.5454

>T109601 WP_109752224.1 NZ_CP031648:c6298461-6298159 [Pseudomonas fluorescens]
MIEFEHSRVFSSWLSGLKDISGKARIIARLRSAEHGNFGDCEPVGSAVYEMRIHSGPGYRVYFSRRGPVFYLLLVGGDKS
TQKRDITRAIQMAQTMGNEE

Download         Length: 303 bp

>T109601 NZ_CP031648:c6298461-6298159 [Pseudomonas fluorescens]
ATGATCGAATTTGAACACTCCCGAGTATTTTCAAGCTGGCTTAGCGGGTTGAAGGACATCTCTGGGAAGGCTCGCATCAT
CGCCAGGCTTCGATCTGCAGAGCATGGAAATTTTGGTGATTGCGAACCGGTGGGCAGCGCAGTATATGAGATGCGTATTC
ACTCGGGTCCGGGCTACAGAGTGTACTTCTCCCGTCGAGGCCCCGTGTTTTATTTACTGCTTGTGGGAGGTGACAAATCG
ACTCAGAAACGGGATATCACACGCGCTATTCAAATGGCGCAAACCATGGGCAATGAGGAGTGA

Antitoxin


Download         Length: 97 a.a.        Molecular weight: 10431.98 Da        Isoelectric Point: 4.8096

>AT109601 WP_109752223.1 NZ_CP031648:c6298155-6297865 [Pseudomonas fluorescens]
MTEEFTRFDAATYLKTPEEMAAYLDACFEEDAGDGVLVRAALNDIARAKGMTQIARDAGLGRESLYKALGSAGNPEFTTI
MKVMKVLGLRLHATTI

Download         Length: 291 bp

>AT109601 NZ_CP031648:c6298155-6297865 [Pseudomonas fluorescens]
ATGACCGAGGAATTCACACGTTTCGATGCAGCCACCTACCTCAAGACGCCTGAGGAAATGGCCGCATATCTGGATGCCTG
TTTTGAAGAAGATGCGGGTGACGGCGTACTGGTTCGAGCAGCTCTTAACGATATCGCCAGGGCAAAAGGCATGACGCAAA
TTGCCCGTGATGCGGGCCTGGGGCGAGAGAGTCTTTACAAAGCACTGGGAAGTGCGGGTAATCCAGAGTTCACAACTATC
ATGAAAGTCATGAAAGTTTTGGGCTTGAGGTTACATGCTACAACCATTTAA

Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure

Antitoxin

Source ID Structure

References