Detailed information of TA system    

insolicoBioinformatically predicted

Overview


TA module


Type VIII Classification (family/domain) SdsR-RyeA/-
Location 1943148..1943293 Replicon chromosome
Accession NZ_CP031613
Organism Klebsiella pneumoniae strain ZYST1

Toxin (RNA)


Gene name SdsR
Locus tag -
Coordinates 1943184..1943286 (+)

Antitoxin (RNA)


Gene name RyeA
Locus tag -
Coordinates 1943148..1943293 (-)

Genomic Context


Locus tag Coordinates Strand Size (bp) Protein ID Product Description
DWV03_RS09815 1938278..1940338 + 2061 WP_004151449.1 oligopeptidase B -
DWV03_RS09820 1940342..1941001 - 660 WP_002911407.1 exodeoxyribonuclease X -
DWV03_RS09825 1941080..1941310 - 231 WP_002911406.1 DNA polymerase III subunit theta -
DWV03_RS09830 1941423..1941797 + 375 WP_004151448.1 CopC domain-containing protein YobA -
DWV03_RS09835 1941801..1942670 + 870 WP_009307538.1 copper homeostasis membrane protein CopD -
DWV03_RS09840 1942687..1943025 + 339 WP_009307539.1 YebY family protein -
- 1943148..1943293 - 146 - - Antitoxin
- 1943184..1943286 + 103 - - Toxin
DWV03_RS28740 1943662..1943805 - 144 WP_002911398.1 Ecr family regulatory small membrane protein -
DWV03_RS09850 1943910..1944878 - 969 WP_004151446.1 VirK/YbjX family protein -
DWV03_RS09855 1945035..1945688 + 654 WP_009307541.1 protein-serine/threonine phosphatase -
DWV03_RS09860 1945685..1945876 - 192 WP_002911395.1 YebW family protein -
DWV03_RS09865 1945974..1946213 - 240 WP_002911393.1 YebV family protein -
DWV03_RS09870 1946329..1947762 - 1434 WP_004148845.1 16S rRNA (cytosine(1407)-C(5))-methyltransferase RsmF -

Associated MGEs


MGE
detail
Similar
MGEs
Relative
position
MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Sequences


Toxin        


Download         Length: 103 bp

>T109549 NZ_CP031613:1943184-1943286 [Klebsiella pneumoniae]
GCAAGGCGACTTAGCCTGCATTAATGCCAACTTTTAGCGCACGGCTCTCTCCCAAGAGCCATTTCCCTGGACCGAATACA
GGAATCGTATTCGGTCTCTTTTT

Antitoxin


Download         Length: 146 bp

>AT109549 NZ_CP031613:c1943293-1943148 [Klebsiella pneumoniae]
TAAAGATAAAAAGAGACCGAATACGATTCCTGTATTCGGTCCAGGGAAATGGCTCTTGGGAGAGAGCCGTGCGCTAAAAG
TTGGCATTAATGCAGGCTAAGTCGCCTTGCACTATAAGAATAGTTTAACGCGTCAGCTTTTCCAGT

Structures


Antitoxin

Download structure file

Antitoxin

Download structure file

References