Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type II Classification (family/domain) EcnAB/-
Location 4657674..4658039 Replicon chromosome
Accession NZ_CP031607
Organism Xanthomonas hortorum strain VT106

Toxin (Protein)


Gene name EcnB Uniprot ID V7Z935
Locus tag DYQ48_RS20795 Protein ID WP_006451341.1
Coordinates 4657674..4657808 (-) Length 45 a.a.

Antitoxin (Protein)


Gene name EcnA Uniprot ID V7Z8F2
Locus tag DYQ48_RS20800 Protein ID WP_006451340.1
Coordinates 4657887..4658039 (-) Length 51 a.a.

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
DYQ48_RS20780 4654608..4655552 - 945 WP_006451344.1 MBL fold metallo-hydrolase -
DYQ48_RS20785 4655760..4657049 - 1290 WP_074056473.1 tryptophan--tRNA ligase -
DYQ48_RS20790 4657223..4657432 - 210 WP_006451342.1 CsbD family protein -
DYQ48_RS20795 4657674..4657808 - 135 WP_006451341.1 entericidin A/B family lipoprotein Toxin
DYQ48_RS20800 4657887..4658039 - 153 WP_006451340.1 entericidin A/B family lipoprotein Antitoxin
DYQ48_RS20805 4658149..4659072 - 924 WP_095575354.1 arginase -
DYQ48_RS20810 4659534..4659986 + 453 WP_006452080.1 roadblock/LC7 domain-containing protein -
DYQ48_RS20815 4660050..4660409 + 360 WP_006452081.1 hypothetical protein -
DYQ48_RS20820 4660501..4661418 + 918 WP_154844954.1 hypothetical protein -
DYQ48_RS20825 4661415..4661957 + 543 WP_154844955.1 GTPase -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin

Entericidin A/B

(23-42)

Antitoxin

Entericidin A/B

(23-42)


Sequences

Toxin        


Download         Length: 45 a.a.        Molecular weight: 4493.34 Da        Isoelectric Point: 9.3487

>T109521 WP_006451341.1 NZ_CP031607:c4657808-4657674 [Xanthomonas hortorum]
MKRAIMLLVLSVFSVGMLAGCNTVAGAGKDVQGAGEKVEDAARK

Download         Length: 135 bp

>T109521 NZ_CP031607:c4657808-4657674 [Xanthomonas hortorum]
ATGAAGCGTGCAATTATGCTGCTGGTGCTGTCGGTGTTTTCGGTCGGTATGCTGGCGGGTTGCAACACCGTCGCAGGTGC
TGGCAAGGACGTGCAGGGCGCTGGCGAGAAAGTGGAAGACGCTGCGCGCAAGTGA

Antitoxin


Download         Length: 51 a.a.        Molecular weight: 5168.11 Da        Isoelectric Point: 8.2782

>AT109521 WP_006451340.1 NZ_CP031607:c4658039-4657887 [Xanthomonas hortorum]
MKRLLTLMVLGLFSAGVMTGCNTMAGAGKDMQGAGEKVEKKADNCSDGKC

Download         Length: 153 bp

>AT109521 NZ_CP031607:c4658039-4657887 [Xanthomonas hortorum]
ATGAAGCGACTGCTGACACTGATGGTGCTAGGCCTGTTTTCGGCTGGCGTGATGACTGGCTGCAACACCATGGCCGGCGC
CGGCAAGGACATGCAGGGCGCAGGTGAGAAGGTCGAAAAGAAGGCCGATAATTGCAGCGACGGCAAGTGCTGA

Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure
AlphaFold DB A0A6V7EZD1

Antitoxin

Source ID Structure
AlphaFold DB A0A2N7V051

References