Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type II Classification (family/domain) relBE/YoeB-YefM
Location 3723954..3724459 Replicon chromosome
Accession NZ_CP031607
Organism Xanthomonas hortorum strain VT106

Toxin (Protein)


Gene name relE Uniprot ID A0A6V7D3A5
Locus tag DYQ48_RS16245 Protein ID WP_074056859.1
Coordinates 3724202..3724459 (+) Length 86 a.a.

Antitoxin (Protein)


Gene name relE Uniprot ID F0BZS9
Locus tag DYQ48_RS16240 Protein ID WP_006448404.1
Coordinates 3723954..3724205 (+) Length 84 a.a.

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
DYQ48_RS16220 3719326..3720480 - 1155 WP_154844815.1 2-methylcitrate synthase -
DYQ48_RS16225 3720556..3721452 - 897 WP_074056861.1 methylisocitrate lyase -
DYQ48_RS16230 3721580..3723199 + 1620 WP_180334374.1 propionate catabolism operon regulatory protein PrpR -
DYQ48_RS16235 3723442..3723768 - 327 WP_006448403.1 hypothetical protein -
DYQ48_RS16240 3723954..3724205 + 252 WP_006448404.1 type II toxin-antitoxin system prevent-host-death family antitoxin Antitoxin
DYQ48_RS16245 3724202..3724459 + 258 WP_074056859.1 Txe/YoeB family addiction module toxin Toxin
DYQ48_RS16255 3724974..3725327 - 354 WP_003483889.1 PilZ domain-containing protein -
DYQ48_RS16260 3725324..3726283 - 960 WP_006448409.1 DNA polymerase III subunit delta' -
DYQ48_RS16265 3726280..3727389 - 1110 WP_074056858.1 endolytic transglycosylase MltG -
DYQ48_RS16270 3727405..3728760 - 1356 WP_074056857.1 aminodeoxychorismate synthase component I -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin

Toxin YoeB

(2-84)

Antitoxin

Type II toxin-antitoxin system, antitoxin Phd/YefM

(1-74)


Sequences

Toxin        


Download         Length: 86 a.a.        Molecular weight: 10156.66 Da        Isoelectric Point: 9.6587

>T109520 WP_074056859.1 NZ_CP031607:3724202-3724459 [Xanthomonas hortorum]
VILQFADNAWEDYLYWQQTDKKMLKRINELIKAIQRDPFQGIGKPEPLRHALAGYWSRRINDEHRIVYKAENGILLIAQA
RYHYG

Download         Length: 258 bp

>T109520 NZ_CP031607:3724202-3724459 [Xanthomonas hortorum]
GTGATTCTGCAGTTTGCTGACAATGCCTGGGAGGACTACCTCTACTGGCAACAGACCGACAAGAAGATGCTCAAACGCAT
CAACGAGTTGATCAAGGCCATTCAGCGCGATCCTTTCCAGGGCATCGGCAAACCCGAACCGTTGCGCCATGCGCTGGCGG
GCTACTGGTCACGCCGCATCAACGACGAACACCGGATTGTCTACAAGGCCGAGAACGGCATCCTGCTGATTGCTCAGGCG
CGCTACCACTACGGGTAA

Antitoxin


Download         Length: 84 a.a.        Molecular weight: 9255.48 Da        Isoelectric Point: 4.6536

>AT109520 WP_006448404.1 NZ_CP031607:3723954-3724205 [Xanthomonas hortorum]
MDTITYSAARASLADTMDRVVNDHEPVIITRSGERAVVMVSLEDYKAMEETAYLLRSPKSAQRLLESIAQLEAGRGKERE
LAE

Download         Length: 252 bp

>AT109520 NZ_CP031607:3723954-3724205 [Xanthomonas hortorum]
ATGGACACCATCACCTACAGCGCCGCGCGTGCCTCTCTGGCCGACACCATGGACCGTGTCGTCAATGACCACGAGCCGGT
GATCATCACGCGCAGCGGTGAGCGCGCCGTGGTCATGGTGTCGCTGGAAGATTACAAGGCCATGGAAGAGACCGCCTACC
TGTTGCGCAGCCCGAAGAGTGCGCAACGGCTGCTGGAATCCATTGCCCAGCTTGAGGCCGGTCGCGGCAAGGAACGGGAA
CTGGCTGAGTGA

Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure
AlphaFold DB A0A6V7D3A5

Antitoxin

Source ID Structure
AlphaFold DB A0A0G8MAJ7

References