Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type II Classification (family/domain) relBE/RHH(antitoxin)
Location 3118324..3118883 Replicon chromosome
Accession NZ_CP031606
Organism Pseudomonas sp. phDV1

Toxin (Protein)


Gene name relE Uniprot ID -
Locus tag DZC76_RS15015 Protein ID WP_108235141.1
Coordinates 3118593..3118883 (+) Length 97 a.a.

Antitoxin (Protein)


Gene name relB Uniprot ID -
Locus tag DZC76_RS15010 Protein ID WP_108235142.1
Coordinates 3118324..3118596 (+) Length 91 a.a.

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
DZC76_RS14995 3114352..3115661 - 1310 Protein_2865 AMP-binding protein -
DZC76_RS15000 3115770..3116909 - 1140 WP_116619260.1 acyl-CoA dehydrogenase family protein -
DZC76_RS15005 3117073..3118071 + 999 WP_116619262.1 AraC family transcriptional regulator -
DZC76_RS15010 3118324..3118596 + 273 WP_108235142.1 ribbon-helix-helix protein, CopG family Antitoxin
DZC76_RS15015 3118593..3118883 + 291 WP_108235141.1 type II toxin-antitoxin system RelE/ParE family toxin Toxin
DZC76_RS15020 3119142..3120524 - 1383 WP_116619264.1 GHKL domain-containing protein -
DZC76_RS15025 3120521..3121198 - 678 WP_116619266.1 response regulator transcription factor -
DZC76_RS15030 3121265..3121870 - 606 WP_108235139.1 outer membrane beta-barrel protein -
DZC76_RS15035 3121983..3123155 - 1173 WP_100546803.1 MFS transporter -
DZC76_RS15040 3123391..3123558 + 168 WP_039964770.1 periplasmic nitrate reductase, NapE protein -
DZC76_RS15045 3123587..3123847 + 261 WP_003461524.1 chaperone NapD -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin

Toxin-antitoxin system, RelE/ParE toxin family

(4-91)

Antitoxin

Ribbon-helix-helix protein, CopG

(4-40)


Sequences

Toxin        


Download         Length: 97 a.a.        Molecular weight: 10857.50 Da        Isoelectric Point: 6.7178

>T109516 WP_108235141.1 NZ_CP031606:3118593-3118883 [Pseudomonas sp. phDV1]
VRLAYSENAVADLVRLREFIAENDPLAAARVAAELLSRIENLCLYPEMGRAVELAPSPKAIRDAVFGKYIVRYSAHTETI
VILRIWHHNEDRTPSI

Download         Length: 291 bp

>T109516 NZ_CP031606:3118593-3118883 [Pseudomonas sp. phDV1]
GTGAGACTGGCCTACTCAGAAAACGCGGTGGCAGACCTCGTTCGCCTGCGCGAATTCATAGCAGAGAACGATCCTCTTGC
TGCTGCACGCGTTGCAGCAGAGCTCCTTTCTCGCATCGAGAATCTTTGTCTATATCCAGAAATGGGCCGCGCTGTTGAGC
TTGCTCCAAGCCCAAAAGCCATTCGAGACGCAGTTTTCGGAAAATATATAGTCCGCTATTCAGCCCACACAGAAACTATC
GTCATTCTTCGTATATGGCACCACAACGAAGACCGTACACCAAGCATCTAA

Antitoxin


Download         Length: 91 a.a.        Molecular weight: 10274.51 Da        Isoelectric Point: 4.4573

>AT109516 WP_108235142.1 NZ_CP031606:3118324-3118596 [Pseudomonas sp. phDV1]
MSVTTVRLQPELEENLGAMAEKLQRSKSWLINQALREFFERQELEQNRWQETLQAMESVAQGRVVSGEAVTAWLQSWGTD
NELSPPKAGQ

Download         Length: 273 bp

>AT109516 NZ_CP031606:3118324-3118596 [Pseudomonas sp. phDV1]
ATGAGCGTCACAACCGTCCGGCTTCAACCGGAGCTCGAAGAAAATCTTGGCGCTATGGCCGAGAAGCTTCAGAGAAGTAA
AAGTTGGCTTATTAATCAAGCGCTTAGAGAGTTCTTTGAGCGCCAGGAGCTAGAGCAGAACCGCTGGCAAGAAACACTGC
AAGCGATGGAGTCAGTGGCGCAGGGCCGAGTTGTATCCGGCGAAGCTGTGACTGCCTGGCTGCAAAGCTGGGGCACCGAC
AATGAGCTATCCCCACCAAAGGCTGGTCAGTGA

Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure

Antitoxin

Source ID Structure

References