Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type II Classification (family/domain) vapBC/VapC-YefM
Location 886500..887176 Replicon chromosome
Accession NZ_CP031606
Organism Pseudomonas sp. phDV1

Toxin (Protein)


Gene name vapC Uniprot ID -
Locus tag DZC76_RS04050 Protein ID WP_084340296.1
Coordinates 886751..887176 (+) Length 142 a.a.

Antitoxin (Protein)


Gene name vapB Uniprot ID W6QR28
Locus tag DZC76_RS04045 Protein ID WP_004424728.1
Coordinates 886500..886751 (+) Length 84 a.a.

Genomic Context

DZC76_RS04030DZC76_RS04045DZC76_RS04050DZC76_RS04055DZC76_RS04060DZC76_RS04065DZC76_RS04070DZC76_RS04075DZC76_RS04035DZC76_RS04040
Location: 883006..885663 (2658 bp)
Type: Others
Protein ID: WP_116617931.1
Location: 886500..886751 (252 bp)
Type: Antitoxin
Protein ID: WP_004424728.1
Location: 886751..887176 (426 bp)
Type: Toxin
Protein ID: WP_084340296.1
Location: 887286..888821 (1536 bp)
Type: Others
Protein ID: WP_004424723.1
Location: 888818..889360 (543 bp)
Type: Others
Protein ID: WP_004424722.1
Location: 889371..890513 (1143 bp)
Type: Others
Protein ID: WP_116617932.1
Location: 890516..891178 (663 bp)
Type: Others
Protein ID: WP_116617933.1
Location: 891153..891767 (615 bp)
Type: Others
Protein ID: WP_074855320.1
Location: 885666..885947 (282 bp)
Type: Others
Protein ID: WP_004424733.1
Location: 885944..886234 (291 bp)
Type: Others
Protein ID: WP_004424730.1
ToxinAntitoxinOther genes
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Locus tag
Coordinates
Strand
Size (bp)
Protein ID
Product
Description
DZC76_RS04030883006..885663+2658WP_116617931.1CRISPR-associated helicase Cas3'-
DZC76_RS04035885666..885947-282WP_004424733.1type II toxin-antitoxin system mRNA interferase toxin, RelE/StbE family-
DZC76_RS04040885944..886234-291WP_004424730.1hypothetical protein-
DZC76_RS04045886500..886751+252WP_004424728.1type II toxin-antitoxin system Phd/YefM family antitoxinAntitoxin
DZC76_RS04050886751..887176+426WP_084340296.1type II toxin-antitoxin system VapC family toxinToxin
DZC76_RS04055887286..888821+1536WP_004424723.1type I-E CRISPR-associated protein Cse1/CasA-
DZC76_RS04060888818..889360+543WP_004424722.1type I-E CRISPR-associated protein Cse2/CasB-
DZC76_RS04065889371..890513+1143WP_116617932.1type I-E CRISPR-associated protein Cas7/Cse4/CasC-
DZC76_RS04070890516..891178+663WP_116617933.1type I-E CRISPR-associated protein Cas5/CasD-
DZC76_RS04075891153..891767+615WP_074855320.1type I-E CRISPR-associated protein Cas6/Cse3/CasE-

Associated MGEs

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MGE
detail
Similar
MGEs
Relative
position
MGE Type
Cargo ARG
Virulence gene
Coordinates
Length (bp)
No matching records found


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin

PIN domain

(3-121)

Antitoxin

Type II toxin-antitoxin system, antitoxin Phd/YefM

(4-58)


Sequences

Toxin        


Download         Length: 142 a.a.        Molecular weight: 15426.01 Da        Isoelectric Point: 8.0845

>T109513 WP_084340296.1 NZ_CP031606:886751-887176 [Pseudomonas sp. phDV1]
MFVLDTNVVSELRKAKSAKADPRLVAWAQRLLPGQLFISAITVLELETGVLLVERRDPQQGRLLRSWLDSHVLPGFAGRI
LPVDAAVAQRCAQLHVPDPRAERDALIVATALVHGMTVATRNMADFLPTGVALINPWEFAG

Download         Length: 426 bp

>T109513 NZ_CP031606:886751-887176 [Pseudomonas sp. phDV1]
ATGTTCGTCCTCGACACTAATGTCGTGTCCGAACTGCGCAAGGCCAAGAGTGCCAAGGCCGACCCGCGCCTAGTGGCCTG
GGCTCAGCGCCTGCTGCCGGGGCAGTTGTTCATTTCCGCGATCACCGTGCTGGAGCTGGAAACCGGCGTGCTGCTAGTGG
AACGACGCGACCCGCAGCAGGGCCGCCTGCTGCGCTCCTGGCTCGATAGCCATGTACTACCCGGCTTCGCCGGACGCATC
CTGCCGGTCGACGCCGCCGTGGCGCAGCGTTGCGCGCAATTGCATGTCCCCGACCCACGCGCCGAACGCGATGCCTTGAT
CGTGGCCACGGCATTGGTGCATGGCATGACAGTCGCCACACGCAACATGGCGGACTTTCTGCCCACAGGCGTGGCACTGA
TCAACCCTTGGGAGTTTGCTGGCTAA

Antitoxin


Download         Length: 84 a.a.        Molecular weight: 8989.20 Da        Isoelectric Point: 5.6492

>AT109513 WP_004424728.1 NZ_CP031606:886500-886751 [Pseudomonas sp. phDV1]
MQTILTSREFNQDASGAKRAAKHGPVFITDRGKPAHVLLSIEEYQRLTGGPGSIIDLLAMPTVEDIEFEAPRAQGLSRPA
DLS

Download         Length: 252 bp

>AT109513 NZ_CP031606:886500-886751 [Pseudomonas sp. phDV1]
ATGCAAACCATCCTTACCAGTCGCGAGTTCAATCAGGACGCCAGTGGTGCCAAGCGTGCTGCCAAACATGGGCCGGTCTT
TATCACGGATCGTGGCAAACCGGCTCATGTGCTGCTGAGCATCGAGGAATACCAGCGTCTGACCGGCGGCCCCGGCAGCA
TCATCGATCTGCTGGCCATGCCGACAGTCGAGGACATCGAGTTCGAGGCGCCGCGTGCGCAAGGTTTGTCGCGCCCGGCG
GATTTGAGCTGA

Similar Proteins

Only experimentally validated proteins are listed.

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Protein
Organism
Identities (%)
Coverage (%)
Ha-value
No matching records found
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Protein
Organism
Identities (%)
Coverage (%)
Ha-value
No matching records found

Structures

Toxin

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Source
ID
Structure
No matching records found

Antitoxin

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Source
ID
Structure
AlphaFold DBW6QR28

References