Detailed information of TA system    

insolicoBioinformatically predicted

Overview


TA module


Type II Classification (family/domain) parDE/RelE-RHH
Location 885666..886234 Replicon chromosome
Accession NZ_CP031606
Organism Pseudomonas sp. phDV1

Toxin (Protein)


Gene name parE Uniprot ID W6QTT6
Locus tag DZC76_RS04035 Protein ID WP_004424733.1
Coordinates 885666..885947 (-) Length 94 a.a.

Antitoxin (Protein)


Gene name parD Uniprot ID W6RBZ2
Locus tag DZC76_RS04040 Protein ID WP_004424730.1
Coordinates 885944..886234 (-) Length 97 a.a.

Genomic Context


DZC76_RS04030DZC76_RS04045DZC76_RS04050DZC76_RS04055DZC76_RS04060DZC76_RS04065DZC76_RS04070DZC76_RS04035DZC76_RS04040
Location: 883006..885663 (2658 bp)
Type: Others
Protein ID: WP_116617931.1
Location: 886500..886751 (252 bp)
Type: Others
Protein ID: WP_004424728.1
Location: 886751..887176 (426 bp)
Type: Others
Protein ID: WP_084340296.1
Location: 887286..888821 (1536 bp)
Type: Others
Protein ID: WP_004424723.1
Location: 888818..889360 (543 bp)
Type: Others
Protein ID: WP_004424722.1
Location: 889371..890513 (1143 bp)
Type: Others
Protein ID: WP_116617932.1
Location: 890516..891178 (663 bp)
Type: Others
Protein ID: WP_116617933.1
Location: 885666..885947 (282 bp)
Type: Toxin
Protein ID: WP_004424733.1
Location: 885944..886234 (291 bp)
Type: Antitoxin
Protein ID: WP_004424730.1
ToxinAntitoxinOther genes
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Locus tag
Coordinates
Strand
Size (bp)
Protein ID
Product
Description
DZC76_RS04030883006..885663+2658WP_116617931.1CRISPR-associated helicase Cas3'-
DZC76_RS04035885666..885947-282WP_004424733.1type II toxin-antitoxin system mRNA interferase toxin, RelE/StbE familyToxin
DZC76_RS04040885944..886234-291WP_004424730.1hypothetical proteinAntitoxin
DZC76_RS04045886500..886751+252WP_004424728.1type II toxin-antitoxin system Phd/YefM family antitoxin-
DZC76_RS04050886751..887176+426WP_084340296.1type II toxin-antitoxin system VapC family toxin-
DZC76_RS04055887286..888821+1536WP_004424723.1type I-E CRISPR-associated protein Cse1/CasA-
DZC76_RS04060888818..889360+543WP_004424722.1type I-E CRISPR-associated protein Cse2/CasB-
DZC76_RS04065889371..890513+1143WP_116617932.1type I-E CRISPR-associated protein Cas7/Cse4/CasC-
DZC76_RS04070890516..891178+663WP_116617933.1type I-E CRISPR-associated protein Cas5/CasD-

Associated MGEs


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MGE
detail
Similar
MGEs
Relative
position
MGE Type
Cargo ARG
Virulence gene
Coordinates
Length (bp)
No matching records found


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains


Predicted by InterproScan

Toxin

(4-89)

Antitoxin


No domain identified.



Sequences


Toxin        


Download         Length: 94 a.a.        Molecular weight: 10565.07 Da        Isoelectric Point: 8.6765

>T109512 WP_004424733.1 NZ_CP031606:c885947-885666 [Pseudomonas sp. phDV1]
VKLAWTRLALNDRQAIRSYIAQDNPIATLALDELFTEKASRLADHPGLGRPGRVSGTRELVVHQHDLMIYDLVNDQVRIL
RVLHTARQWPSAD

Download         Length: 282 bp

>T109512 NZ_CP031606:c885947-885666 [Pseudomonas sp. phDV1]
GTGAAACTGGCCTGGACGCGTCTTGCGCTGAACGACCGCCAAGCCATCCGCAGTTATATCGCCCAGGACAATCCCATTGC
CACCCTGGCGCTGGATGAATTGTTCACGGAGAAGGCCAGCCGCCTGGCCGATCATCCCGGCTTGGGGCGACCAGGCCGGG
TAAGCGGCACTCGCGAACTGGTTGTGCATCAGCACGATCTGATGATCTACGACCTGGTCAATGACCAAGTACGGATACTC
CGCGTGTTGCATACGGCCCGCCAGTGGCCAAGTGCAGACTGA

Antitoxin


Download         Length: 97 a.a.        Molecular weight: 10878.08 Da        Isoelectric Point: 4.7266

>AT109512 WP_004424730.1 NZ_CP031606:c886234-885944 [Pseudomonas sp. phDV1]
MSEATFTFRVDDALKSEFAQAAKARDRTGAQLLRDFMRDFVRQQQEAAEHDVWLRRQVQMGLDSANAGELLSSEEVEAEA
AAWRAEMRRKLDSAAS

Download         Length: 291 bp

>AT109512 NZ_CP031606:c886234-885944 [Pseudomonas sp. phDV1]
ATGAGTGAAGCCACCTTTACCTTTCGCGTAGACGACGCCCTGAAAAGCGAATTTGCCCAGGCAGCCAAGGCCCGCGACCG
TACCGGCGCGCAGTTGCTGCGCGACTTCATGCGCGACTTCGTCCGGCAGCAGCAAGAGGCCGCCGAGCACGATGTCTGGC
TGCGCCGCCAGGTACAGATGGGGCTGGATTCGGCCAATGCCGGTGAGTTGCTCAGCAGCGAAGAGGTCGAAGCCGAAGCC
GCCGCATGGCGCGCTGAAATGCGCCGCAAGCTGGACAGCGCCGCGTCGTGA

Similar Proteins


Only experimentally validated proteins are listed.

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Protein
Organism
Identities (%)
Coverage (%)
Ha-value
No matching records found
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Protein
Organism
Identities (%)
Coverage (%)
Ha-value
No matching records found

Structures


Toxin

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Source
ID
Structure
AlphaFold DBW6QTT6


Antitoxin

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Source
ID
Structure
AlphaFold DBW6RBZ2

References