Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type II Classification (family/domain) relBE/Phd(antitoxin)
Location 741839..742380 Replicon chromosome
Accession NZ_CP031606
Organism Pseudomonas sp. phDV1

Toxin (Protein)


Gene name relE Uniprot ID W6QQQ0
Locus tag DZC76_RS03360 Protein ID WP_039965077.1
Coordinates 741839..742135 (-) Length 99 a.a.

Antitoxin (Protein)


Gene name relB Uniprot ID -
Locus tag DZC76_RS03365 Protein ID WP_116617865.1
Coordinates 742123..742380 (-) Length 86 a.a.

Genomic Context

DZC76_RS03330DZC76_RS03335DZC76_RS03350DZC76_RS03355DZC76_RS03375DZC76_RS03385DZC76_RS03390DZC76_RS03345DZC76_RS03360DZC76_RS03365DZC76_RS03370DZC76_RS03380DZC76_RS03395
Location: 737443..737586 (144 bp)
Type: Others
Protein ID: WP_116617861.1
Location: 737677..737970 (294 bp)
Type: Others
Protein ID: Protein_654
Location: 739074..740516 (1443 bp)
Type: Others
Protein ID: WP_116617864.1
Location: 740516..741835 (1320 bp)
Type: Others
Protein ID: WP_004425062.1
Location: 743817..744593 (777 bp)
Type: Others
Protein ID: WP_116617866.1
Location: 745860..746108 (249 bp)
Type: Others
Protein ID: WP_004425048.1
Location: 746177..746455 (279 bp)
Type: Others
Protein ID: WP_004425044.1
Location: 738349..738819 (471 bp)
Type: Others
Protein ID: WP_162884207.1
Location: 741839..742135 (297 bp)
Type: Toxin
Protein ID: WP_039965077.1
Location: 742123..742380 (258 bp)
Type: Antitoxin
Protein ID: WP_116617865.1
Location: 742449..743573 (1125 bp)
Type: Others
Protein ID: WP_004425056.1
Location: 744594..745619 (1026 bp)
Type: Others
Protein ID: WP_116617867.1
Location: 746717..747193 (477 bp)
Type: Others
Protein ID: WP_116617868.1
ToxinAntitoxinOther genes
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Locus tag
Coordinates
Strand
Size (bp)
Protein ID
Product
Description
DZC76_RS03330737443..737586+144WP_116617861.1DUF2474 domain-containing protein-
DZC76_RS03335737677..737970+294Protein_654aldehyde dehydrogenase family protein-
DZC76_RS03345738349..738819-471WP_162884207.1hypothetical protein-
DZC76_RS03350739074..740516+1443WP_116617864.1TldD/PmbA family protein-
DZC76_RS03355740516..741835+1320WP_004425062.1Zn-dependent protease-
DZC76_RS03360741839..742135-297WP_039965077.1type II toxin-antitoxin system RelE/ParE family toxinToxin
DZC76_RS03365742123..742380-258WP_116617865.1type II toxin-antitoxin system Phd/YefM family antitoxinAntitoxin
DZC76_RS03370742449..743573-1125WP_004425056.1class I SAM-dependent methyltransferase-
DZC76_RS03375743817..744593+777WP_116617866.1ferredoxin--NADP reductase-
DZC76_RS03380744594..745619-1026WP_116617867.1hemolysin family protein-
DZC76_RS03385745860..746108+249WP_004425048.1YdcH family protein-
DZC76_RS03390746177..746455+279WP_004425044.1DUF465 domain-containing protein-
DZC76_RS03395746717..747193-477WP_116617868.1GNAT family N-acetyltransferase-

Associated MGEs

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MGE
detail
Similar
MGEs
Relative
position
MGE Type
Cargo ARG
Virulence gene
Coordinates
Length (bp)
No matching records found


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin

Toxin-antitoxin system, RelE/ParE toxin family

(4-90)

Antitoxin

Type II toxin-antitoxin system, antitoxin Phd/YefM

(1-73)


Sequences

Toxin        


Download         Length: 99 a.a.        Molecular weight: 11393.23 Da        Isoelectric Point: 5.5623

>T109511 WP_039965077.1 NZ_CP031606:c742135-741839 [Pseudomonas sp. phDV1]
MAEIVWTNTALEQLDDLAHYIALDKPDAARALVMRAVETVSRLADFPLSGRVPDELPHSVYREIVIPPCRIFYRYTDTTV
FIIHIMREERVLRAHMLE

Download         Length: 297 bp

>T109511 NZ_CP031606:c742135-741839 [Pseudomonas sp. phDV1]
ATGGCTGAAATAGTCTGGACGAACACCGCCCTCGAGCAGCTCGACGATCTCGCGCACTACATCGCCCTCGACAAACCGGA
CGCCGCGCGAGCGCTGGTCATGAGGGCCGTTGAAACGGTTTCACGGTTAGCAGACTTTCCCCTGTCGGGCCGCGTTCCGG
ATGAGCTTCCACACTCGGTGTACCGCGAAATCGTCATCCCACCCTGCCGAATTTTCTACCGTTATACAGACACAACGGTT
TTCATCATCCACATCATGCGAGAGGAGCGCGTGCTGCGCGCCCACATGCTCGAGTGA

Antitoxin


Download         Length: 86 a.a.        Molecular weight: 9772.28 Da        Isoelectric Point: 7.3181

>AT109511 WP_116617865.1 NZ_CP031606:c742380-742123 [Pseudomonas sp. phDV1]
MKVELVTNLKRQATKILADLHESKEPVLITEHGMPSAYLVDVDDYQFMQKRLALLDALARGERAVIEGNTQNHEQAKERL
SKWLK

Download         Length: 258 bp

>AT109511 NZ_CP031606:c742380-742123 [Pseudomonas sp. phDV1]
ATGAAAGTCGAGTTGGTCACCAACCTGAAGCGGCAAGCCACCAAGATTCTGGCCGACCTTCACGAGTCCAAAGAGCCCGT
ACTGATCACCGAGCATGGAATGCCCTCGGCTTATCTGGTGGATGTCGATGATTATCAGTTCATGCAGAAGCGTCTTGCCC
TTCTGGATGCACTGGCTCGCGGTGAGCGCGCCGTTATCGAGGGCAACACCCAGAACCATGAGCAGGCCAAGGAACGGCTG
AGCAAATGGCTGAAATAG

Similar Proteins

Only experimentally validated proteins are listed.

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Protein
Organism
Identities (%)
Coverage (%)
Ha-value
No matching records found
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Protein
Organism
Identities (%)
Coverage (%)
Ha-value
No matching records found

Structures

Toxin

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Source
ID
Structure
AlphaFold DBW6QQQ0

Antitoxin

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Source
ID
Structure
No matching records found

References