Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type II Classification (family/domain) parDE/CC2985(antitoxin)
Location 3217492..3218030 Replicon chromosome
Accession NZ_CP031598
Organism Roseovarius indicus strain DSM 26383

Toxin (Protein)


Gene name parE Uniprot ID -
Locus tag RIdsm_RS15355 Protein ID WP_057815874.1
Coordinates 3217492..3217791 (-) Length 100 a.a.

Antitoxin (Protein)


Gene name parD Uniprot ID -
Locus tag RIdsm_RS15360 Protein ID WP_057815872.1
Coordinates 3217788..3218030 (-) Length 81 a.a.

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
RIdsm_RS15325 3212618..3213859 + 1242 WP_057815881.1 DUF2029 domain-containing protein -
RIdsm_RS15330 3213873..3214433 + 561 WP_057815879.1 acetolactate synthase small subunit -
RIdsm_RS15335 3214434..3214799 - 366 WP_057815877.1 hypothetical protein -
RIdsm_RS15340 3215113..3215850 + 738 WP_082647374.1 helix-turn-helix domain-containing protein -
RIdsm_RS15345 3215971..3217131 + 1161 WP_057815875.1 aromatic ring-hydroxylating dioxygenase subunit alpha -
RIdsm_RS15350 3217158..3217373 + 216 WP_057816197.1 hypothetical protein -
RIdsm_RS15355 3217492..3217791 - 300 WP_057815874.1 type II toxin-antitoxin system RelE/ParE family toxin Toxin
RIdsm_RS15360 3217788..3218030 - 243 WP_057815872.1 type II toxin-antitoxin system ParD family antitoxin Antitoxin
RIdsm_RS15365 3218173..3219315 + 1143 WP_057815870.1 acyl-CoA dehydrogenase family protein -
RIdsm_RS15370 3219312..3220355 + 1044 WP_057815867.1 enoyl-CoA hydratase/isomerase family protein -
RIdsm_RS15375 3220360..3221232 + 873 WP_057815865.1 3-hydroxyisobutyrate dehydrogenase -
RIdsm_RS15380 3221310..3221507 + 198 WP_057815863.1 DUF2892 domain-containing protein -
RIdsm_RS15385 3221633..3221926 + 294 WP_138179212.1 excinuclease ABC subunit A -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin

Toxin-antitoxin system, RelE/ParE toxin family

(5-93)

Antitoxin

Antitoxin ParD

(1-75)


Sequences

Toxin        


Download         Length: 100 a.a.        Molecular weight: 11549.18 Da        Isoelectric Point: 6.2284

>T109499 WP_057815874.1 NZ_CP031598:c3217791-3217492 [Roseovarius indicus]
VSRQILWRPRAEADLDDIWRYTVERWSEGQAVAYLTGLDRTLGVLAEFPETARLREEFVPPVRIHPYRAHLIVFLADERG
LDVVRVVHARANWQAILSE

Download         Length: 300 bp

>T109499 NZ_CP031598:c3217791-3217492 [Roseovarius indicus]
GTGAGCCGCCAGATTCTGTGGCGCCCCAGGGCCGAGGCCGACCTGGACGATATCTGGCGATACACGGTCGAGAGGTGGTC
GGAGGGGCAGGCGGTTGCCTATCTGACGGGGCTCGACCGAACGCTGGGGGTGCTGGCGGAATTTCCGGAGACGGCCCGAT
TGCGGGAAGAGTTCGTGCCGCCTGTGCGTATACATCCCTACAGGGCGCATCTGATCGTTTTCCTGGCGGATGAGCGGGGT
CTGGACGTGGTGCGCGTGGTGCATGCGCGGGCGAACTGGCAGGCAATTCTGTCGGAGTGA

Antitoxin


Download         Length: 81 a.a.        Molecular weight: 8933.07 Da        Isoelectric Point: 5.0914

>AT109499 WP_057815872.1 NZ_CP031598:c3218030-3217788 [Roseovarius indicus]
MATMNVSLPDHMKTCVEARAKGGQYSNVSDYVRDLIRKDLERQQAIGELQGMIEEGLRSGEPQAFDMAGFIDRKTRGQGE

Download         Length: 243 bp

>AT109499 NZ_CP031598:c3218030-3217788 [Roseovarius indicus]
ATGGCCACGATGAACGTCTCCCTTCCCGATCACATGAAAACATGCGTCGAAGCGCGCGCCAAGGGCGGGCAGTACAGCAA
TGTCAGCGATTACGTGCGCGACCTGATCCGGAAGGATCTGGAGCGGCAGCAGGCGATCGGCGAGTTGCAGGGGATGATCG
AGGAGGGGCTTCGGAGCGGCGAGCCGCAGGCGTTCGACATGGCCGGGTTCATTGACAGGAAGACGCGCGGTCAGGGCGAG
TGA

Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure

Antitoxin

Source ID Structure

References