Detailed information of TA system    

insolicoBioinformatically predicted

Overview


TA module


Type VIII Classification (family/domain) SdsR-RyeA/-
Location 4259765..4259910 Replicon chromosome
Accession NZ_CP031577
Organism Klebsiella pneumoniae strain N4b

Toxin (RNA)


Gene name SdsR
Locus tag -
Coordinates 4259801..4259903 (+)

Antitoxin (RNA)


Gene name RyeA
Locus tag -
Coordinates 4259765..4259910 (-)

Genomic Context


Locus tag Coordinates Strand Size (bp) Protein ID Product Description
AXA58_RS21250 4254895..4256955 + 2061 WP_004151449.1 oligopeptidase B -
AXA58_RS21255 4256959..4257618 - 660 WP_002911407.1 exodeoxyribonuclease X -
AXA58_RS21260 4257697..4257927 - 231 WP_002911406.1 DNA polymerase III subunit theta -
AXA58_RS21265 4258040..4258414 + 375 WP_004151448.1 CopC domain-containing protein YobA -
AXA58_RS21270 4258418..4259287 + 870 WP_004189267.1 copper homeostasis membrane protein CopD -
AXA58_RS21275 4259304..4259642 + 339 WP_002911404.1 YebY family protein -
- 4259765..4259910 - 146 - - Antitoxin
- 4259801..4259903 + 103 - - Toxin
AXA58_RS31120 4260279..4260422 - 144 WP_002911398.1 Ecr family regulatory small membrane protein -
AXA58_RS21285 4260527..4261495 - 969 WP_004151446.1 VirK/YbjX family protein -
AXA58_RS21290 4261652..4262305 + 654 WP_002911396.1 protein-serine/threonine phosphatase -
AXA58_RS21295 4262302..4262493 - 192 WP_002911395.1 YebW family protein -
AXA58_RS21300 4262591..4262830 - 240 WP_002911393.1 YebV family protein -
AXA58_RS21305 4262946..4264379 - 1434 WP_004148845.1 16S rRNA (cytosine(1407)-C(5))-methyltransferase RsmF -

Associated MGEs


MGE
detail
Similar
MGEs
Relative
position
MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Sequences


Toxin        


Download         Length: 103 bp

>T109484 NZ_CP031577:4259801-4259903 [Klebsiella pneumoniae]
GCAAGGCGACTTAGCCTGCATTAATGCCAACTTTTAGCGCACGGCTCTCTCCCAAGAGCCATTTCCCTGGACCGAATACA
GGAATCGTATTCGGTCTCTTTTT

Antitoxin


Download         Length: 146 bp

>AT109484 NZ_CP031577:c4259910-4259765 [Klebsiella pneumoniae]
TAAAGATAAAAAGAGACCGAATACGATTCCTGTATTCGGTCCAGGGAAATGGCTCTTGGGAGAGAGCCGTGCGCTAAAAG
TTGGCATTAATGCAGGCTAAGTCGCCTTGCACTATAAGAATAGTTTAACGCGTCAGCTTTTCCAGT

Structures


Antitoxin

Download structure file

Antitoxin

Download structure file

References