Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type IV Classification (family/domain) ykfI-yfjZ/CbtA-CbeA
Location 430431..431110 Replicon chromosome
Accession NZ_CP031571
Organism Enterobacter hormaechei strain N1

Toxin (Protein)


Gene name ykfI Uniprot ID -
Locus tag AXA51_RS02220 Protein ID WP_129541224.1
Coordinates 430769..431110 (+) Length 114 a.a.

Antitoxin (Protein)


Gene name yfjZ Uniprot ID -
Locus tag AXA51_RS02215 Protein ID WP_129541223.1
Coordinates 430431..430748 (+) Length 106 a.a.

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
AXA51_RS02175 425638..426462 + 825 WP_129541216.1 DUF945 domain-containing protein -
AXA51_RS02180 426671..427384 + 714 WP_129541217.1 DeoR family transcriptional regulator -
AXA51_RS02185 427675..428541 + 867 WP_129541218.1 hypothetical protein -
AXA51_RS02190 428635..428855 + 221 Protein_421 DUF905 family protein -
AXA51_RS02195 428975..429433 + 459 WP_129541219.1 antirestriction protein -
AXA51_RS02200 429443..429661 + 219 WP_129541220.1 hypothetical protein -
AXA51_RS02205 429704..430183 + 480 WP_129541221.1 DNA repair protein RadC -
AXA51_RS02210 430192..430413 + 222 WP_129541222.1 DUF987 domain-containing protein -
AXA51_RS02215 430431..430748 + 318 WP_129541223.1 type IV toxin-antitoxin system YeeU family antitoxin Antitoxin
AXA51_RS02220 430769..431110 + 342 WP_129541224.1 TA system toxin CbtA family protein Toxin
AXA51_RS02225 431430..432443 - 1014 WP_023206295.1 tyrosine-type recombinase/integrase -
AXA51_RS02230 432449..432994 - 546 WP_023206294.1 hypothetical protein -
AXA51_RS02235 433020..433670 - 651 WP_095908289.1 phage repressor protein CI -
AXA51_RS02240 433758..433994 + 237 WP_023206292.1 hypothetical protein -
AXA51_RS02245 434029..434538 + 510 WP_015386351.1 phage regulatory CII family protein -
AXA51_RS02250 434546..434746 + 201 WP_015386352.1 DUF2724 domain-containing protein -
AXA51_RS02255 434710..435051 + 342 WP_000963477.1 DUF5347 domain-containing protein -
AXA51_RS02260 435119..435352 + 234 WP_095908288.1 DUF2732 domain-containing protein -
AXA51_RS02265 435352..435579 + 228 WP_095908287.1 TraR/DksA family transcriptional regulator -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)
- inside Prophage - - 425638..469509 43871


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin

CbtA toxin of type IV toxin-antitoxin system

(1-110)

Antitoxin

Antitoxin CbeA

(5-104)


Sequences

Toxin        


Download         Length: 114 a.a.        Molecular weight: 12723.66 Da        Isoelectric Point: 8.9919

>T109439 WP_129541224.1 NZ_CP031571:430769-431110 [Enterobacter hormaechei]
MKLQPATTSRAVKLCLSPVAVWQMLLTRLLEQHYGLTLNDTPFSDKTVIQEHIDAGITLADAVNFLVDKYELVRIDRRGF
SGQEQSPYLRAVDILRARQATGLLRQSRDNAAL

Download         Length: 342 bp

>T109439 NZ_CP031571:430769-431110 [Enterobacter hormaechei]
ATGAAACTTCAACCTGCAACAACTTCGCGGGCGGTAAAGCTCTGCCTGTCACCTGTGGCTGTCTGGCAAATGTTACTGAC
ACGCCTGCTGGAGCAACACTATGGCTTGACCCTGAACGACACGCCGTTCAGTGATAAAACAGTTATTCAGGAACATATTG
ATGCCGGGATTACCCTGGCGGATGCAGTCAACTTCCTGGTAGATAAGTACGAACTGGTTCGTATCGATCGCAGAGGATTT
AGCGGGCAGGAGCAATCACCTTATCTTCGCGCGGTAGATATCCTGCGAGCGCGGCAGGCAACTGGCTTGTTGCGACAAAG
CCGTGATAACGCGGCATTATGA

Antitoxin


Download         Length: 106 a.a.        Molecular weight: 11871.52 Da        Isoelectric Point: 6.3109

>AT109439 WP_129541223.1 NZ_CP031571:430431-430748 [Enterobacter hormaechei]
MSNTTWGLQRDITPRLGARLVQEGNRLHYLADRSSITGKFSEAECLMLDVIFPHFISQMESMLTTGEMNPRHAHCVTLCH
NDFTCEADTLGSCGYVYIAVYPTQR

Download         Length: 318 bp

>AT109439 NZ_CP031571:430431-430748 [Enterobacter hormaechei]
ATGAGCAACACCACATGGGGTCTGCAGCGGGATATCACGCCGCGCCTGGGTGCACGTCTGGTGCAGGAGGGCAACCGGCT
GCACTATCTGGCTGACCGGTCCAGTATTACAGGGAAGTTCAGCGAAGCAGAATGTCTTATGCTGGATGTGATATTTCCAC
ATTTTATCAGCCAGATGGAATCCATGCTGACCACAGGTGAAATGAACCCTCGGCATGCCCACTGCGTCACTCTGTGCCAC
AACGATTTTACCTGCGAAGCCGATACTCTTGGTAGTTGTGGCTACGTATACATCGCTGTTTATCCCACTCAACGCTAA

Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure

Antitoxin

Source ID Structure

References