Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type II Classification (family/domain) ccdAB/CcdA(antitoxin)
Location 1737404..1737957 Replicon chromosome
Accession NZ_CP031515
Organism Dickeya zeae strain EC2

Toxin (Protein)


Gene name ccdB Uniprot ID -
Locus tag DWV07_RS07615 Protein ID WP_019844797.1
Coordinates 1737643..1737957 (+) Length 105 a.a.

Antitoxin (Protein)


Gene name ccdA Uniprot ID -
Locus tag DWV07_RS07610 Protein ID WP_016941021.1
Coordinates 1737404..1737640 (+) Length 79 a.a.

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
DWV07_RS20305 1733999..1734126 - 128 Protein_1477 DNA polymerase V subunit UmuC -
DWV07_RS07590 1734126..1734587 - 462 Protein_1478 hypothetical protein -
DWV07_RS07595 1734914..1735693 + 780 WP_168365428.1 DUF1738 domain-containing protein -
DWV07_RS07605 1736880..1737083 + 204 Protein_1481 DNA primase -
DWV07_RS07610 1737404..1737640 + 237 WP_016941021.1 type II toxin-antitoxin system CcdA family antitoxin Antitoxin
DWV07_RS07615 1737643..1737957 + 315 WP_019844797.1 CcdB family protein Toxin
DWV07_RS07620 1737954..1738175 - 222 WP_168366881.1 mobilization protein mobC -
DWV07_RS07625 1738165..1739064 - 900 WP_168365430.1 AraC family transcriptional regulator -
DWV07_RS07630 1739597..1740088 - 492 WP_038904892.1 DUF2569 domain-containing protein -
DWV07_RS07635 1740252..1741853 + 1602 WP_168366882.1 sigma-54 dependent transcriptional regulator -
DWV07_RS07640 1741957..1742130 - 174 WP_168365431.1 hypothetical protein -
DWV07_RS07645 1742190..1742708 + 519 WP_038904890.1 Hcp family type VI secretion system effector -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin

Toxin CcdB

(2-103)

Antitoxin

Post-segregation antitoxin CcdA

(9-78)


Sequences

Toxin        


Download         Length: 105 a.a.        Molecular weight: 11486.40 Da        Isoelectric Point: 7.9859

>T109312 WP_019844797.1 NZ_CP031515:1737643-1737957 [Dickeya zeae]
MQFTVYGNTGKSAIYPLLLDVTSDIIGQLNRRIVIPLLPVEKYPAGRRPDRLVPVVRLTDGKEYAVMTHELASIPVQALG
AVFCDASQYRNQVKAAIDFLIDGI

Download         Length: 315 bp

>T109312 NZ_CP031515:1737643-1737957 [Dickeya zeae]
ATGCAATTCACCGTATACGGTAATACCGGGAAAAGCGCCATTTACCCGCTGTTGCTCGATGTCACGAGCGATATTATTGG
GCAGTTGAATCGTCGGATAGTGATCCCGTTGCTCCCTGTTGAAAAGTACCCGGCAGGCCGCCGACCGGATCGCCTTGTCC
CCGTCGTCAGGCTGACGGACGGCAAAGAATACGCCGTAATGACGCACGAGCTGGCAAGTATCCCTGTGCAGGCGTTGGGT
GCGGTGTTCTGTGATGCATCGCAGTACCGTAATCAGGTAAAAGCCGCAATAGATTTCCTCATTGACGGCATTTAA

Antitoxin


Download         Length: 79 a.a.        Molecular weight: 9039.06 Da        Isoelectric Point: 5.8500

>AT109312 WP_016941021.1 NZ_CP031515:1737404-1737640 [Dickeya zeae]
MTAKQRNTQSVTMTVERALLVRAREAGINLSATLSTALDAELRRYEAKKWQEENREAIDALNRFHDENGCFSDEYRTF

Download         Length: 237 bp

>AT109312 NZ_CP031515:1737404-1737640 [Dickeya zeae]
ATGACCGCGAAACAACGTAACACGCAGAGCGTGACCATGACGGTAGAGCGTGCCTTACTGGTCCGGGCGCGTGAAGCGGG
CATTAACCTGAGTGCCACGCTGTCAACCGCACTGGATGCGGAGCTTCGCCGTTATGAGGCGAAAAAATGGCAGGAAGAGA
ACAGGGAGGCTATCGACGCATTAAATCGCTTTCATGATGAAAACGGCTGTTTCAGTGACGAATACAGGACGTTTTAA

Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure

Antitoxin

Source ID Structure

References