Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type IV Classification (family/domain) cptAB/Cpta(toxin)
Location 798855..799533 Replicon chromosome
Accession NZ_CP031505
Organism Dickeya fangzhongdai strain LN1

Toxin (Protein)


Gene name cptA Uniprot ID A0A2K8QJH4
Locus tag DYD82_RS03820 Protein ID WP_049854564.1
Coordinates 799102..799533 (+) Length 144 a.a.

Antitoxin (Protein)


Gene name cptB Uniprot ID A0A2K8QSU7
Locus tag DYD82_RS03815 Protein ID WP_023637600.1
Coordinates 798855..799121 (+) Length 89 a.a.

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
DYD82_RS03795 795284..795934 + 651 WP_038917839.1 LysE family translocator -
DYD82_RS03800 796005..796613 - 609 WP_100848933.1 HD domain-containing protein -
DYD82_RS03805 796824..797474 + 651 WP_038917842.1 hemolysin III family protein -
DYD82_RS03810 797564..798544 - 981 WP_100848934.1 tRNA-modifying protein YgfZ -
DYD82_RS03815 798855..799121 + 267 WP_023637600.1 FAD assembly factor SdhE Antitoxin
DYD82_RS03820 799102..799533 + 432 WP_049854564.1 protein YgfX Toxin
DYD82_RS03825 799633..800151 - 519 WP_038662307.1 flavodoxin FldB -
DYD82_RS03830 800280..801605 - 1326 WP_038662304.1 MHS family MFS transporter -
DYD82_RS03835 801868..802767 + 900 WP_038917846.1 site-specific tyrosine recombinase XerD -
DYD82_RS03840 802856..803572 + 717 WP_038917847.1 bifunctional protein-disulfide isomerase/oxidoreductase DsbC -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin

Inner membrane protein YgfX

(2-132)

Antitoxin

Flavinator of succinate dehydrogenase

(8-79)


Sequences

Toxin        


Download         Length: 144 a.a.        Molecular weight: 16793.54 Da        Isoelectric Point: 11.7737

>T109274 WP_049854564.1 NZ_CP031505:799102-799533 [Dickeya fangzhongdai]
VAQWQCDLRVSWRMQLFSLLTHGFLVLMILLAPWPDGYAPLWLGLVTLVVFGFVRSQRIIKSRQGEISLHGENQLHWQQR
DWQIARRPWVMRNGVLLSLRATTGKGHQRLWLASDSMGNEEWRLLRQLLLQHPLQGTESSRHH

Download         Length: 432 bp

>T109274 NZ_CP031505:799102-799533 [Dickeya fangzhongdai]
GTGGCCCAGTGGCAATGTGATTTGCGTGTATCCTGGCGCATGCAGTTGTTTTCTCTGCTGACGCACGGGTTCCTGGTGCT
GATGATCCTGCTGGCTCCCTGGCCGGACGGCTATGCGCCGCTGTGGCTGGGGTTGGTGACGCTGGTGGTGTTCGGTTTCG
TGCGCAGTCAGCGCATCATCAAGTCGCGTCAGGGGGAAATTTCCCTGCATGGGGAAAACCAACTGCACTGGCAACAGCGT
GACTGGCAGATAGCCCGGCGACCGTGGGTGATGCGCAACGGCGTGTTGCTGTCGTTGCGGGCGACGACCGGCAAAGGGCA
TCAGCGCTTGTGGCTGGCGTCAGACAGTATGGGCAATGAAGAGTGGCGGCTGTTGCGCCAACTGTTGCTGCAGCATCCGC
TGCAGGGCACGGAATCCTCCCGCCATCATTAA

Antitoxin


Download         Length: 89 a.a.        Molecular weight: 10544.03 Da        Isoelectric Point: 5.5535

>AT109274 WP_023637600.1 NZ_CP031505:798855-799121 [Dickeya fangzhongdai]
MDINNKSRIHWACRRGMRELDISIMPFFEHEYDTLSDDDKQHFIRLLQCDDPDLFNWLMNHGEPVDPELKRMVSLIQTRN
KDRGPVAM

Download         Length: 267 bp

>AT109274 NZ_CP031505:798855-799121 [Dickeya fangzhongdai]
ATGGACATCAATAACAAATCACGCATTCACTGGGCGTGCAGACGCGGAATGCGTGAACTGGATATTTCCATCATGCCGTT
TTTCGAGCATGAGTACGACACGCTGAGCGACGACGACAAGCAGCATTTCATCCGTCTGTTGCAGTGCGACGATCCCGACT
TGTTCAACTGGCTGATGAACCACGGCGAGCCGGTGGATCCGGAGCTGAAGCGCATGGTTTCCCTTATTCAGACGCGAAAT
AAAGACCGTGGCCCAGTGGCAATGTGA

Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure
AlphaFold DB A0A2K8QJH4

Antitoxin

Source ID Structure
AlphaFold DB A0A2K8QSU7

References