Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type II Classification (family/domain) ataRT/DUF1778(antitoxin)
Location 470652..471394 Replicon chromosome
Accession NZ_CP031505
Organism Dickeya fangzhongdai strain LN1

Toxin (Protein)


Gene name ataT Uniprot ID C6C3X4
Locus tag DYD82_RS02210 Protein ID WP_015855199.1
Coordinates 470652..471131 (-) Length 160 a.a.

Antitoxin (Protein)


Gene name ataR Uniprot ID A0A3N0G0N1
Locus tag DYD82_RS02215 Protein ID WP_019843650.1
Coordinates 471122..471394 (-) Length 91 a.a.

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
DYD82_RS02180 466499..466699 + 201 WP_188726100.1 AlpA family transcriptional regulator -
DYD82_RS02185 466696..467235 + 540 WP_100848772.1 ash family protein -
DYD82_RS02190 467228..469270 + 2043 WP_100848773.1 AAA family ATPase -
DYD82_RS02195 469493..469759 - 267 WP_013316114.1 helix-turn-helix domain-containing protein -
DYD82_RS02200 469865..470077 + 213 Protein_418 transcriptional regulator -
DYD82_RS02205 470222..470623 - 402 WP_100848774.1 hypothetical protein -
DYD82_RS02210 470652..471131 - 480 WP_015855199.1 GNAT family N-acetyltransferase Toxin
DYD82_RS02215 471122..471394 - 273 WP_019843650.1 DUF1778 domain-containing protein Antitoxin
DYD82_RS02220 471660..472778 + 1119 Protein_422 IS3 family transposase -
DYD82_RS02225 473041..473763 - 723 WP_100848775.1 methyltransferase domain-containing protein -
DYD82_RS02230 473771..474028 - 258 WP_049855262.1 YjhX family toxin -
DYD82_RS02235 474481..474819 - 339 WP_100848776.1 hypothetical protein -
DYD82_RS02240 475207..475905 - 699 WP_145958393.1 hypothetical protein -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)
- inside Prophage - - 460706..480573 19867


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin

GNAT domain

(28-147)

Antitoxin

Vibrio phage ICP1, Orf50

(10-85)


Sequences

Toxin        


Download         Length: 160 a.a.        Molecular weight: 17538.30 Da        Isoelectric Point: 9.5367

>T109272 WP_015855199.1 NZ_CP031505:c471131-470652 [Dickeya fangzhongdai]
VGITAPELLLPQHAVVDFHCSEPSLNEWLKRKALKNQTLGASRTFVVCEAGTQRVVGFYALASGSIQRQVAPGAFRRNMP
DPIPVLVLGRLAVDERYQRMGIGAGLLKDAVLRSRNVAQQVGNKALLVHALSDEAKAFYQYWGFVASEIQEHTLLLSLW

Download         Length: 480 bp

>T109272 NZ_CP031505:c471131-470652 [Dickeya fangzhongdai]
GTGGGAATAACGGCACCTGAATTATTGCTGCCTCAACATGCGGTTGTGGATTTTCATTGTTCAGAGCCGTCATTGAATGA
ATGGCTGAAACGCAAGGCGTTAAAAAATCAGACACTGGGCGCTTCACGCACCTTCGTGGTGTGTGAAGCCGGTACACAGC
GTGTGGTGGGGTTCTATGCCCTCGCGTCGGGTAGCATCCAGCGTCAGGTTGCGCCGGGCGCATTCCGGCGCAATATGCCT
GACCCCATTCCTGTTCTGGTACTTGGCCGATTAGCCGTTGATGAACGTTATCAACGCATGGGGATCGGTGCCGGGCTCCT
GAAAGATGCGGTACTCCGCTCCCGCAATGTAGCGCAGCAGGTAGGCAACAAAGCGTTATTGGTACATGCGTTATCTGATG
AGGCAAAAGCGTTCTACCAATACTGGGGTTTTGTCGCGTCAGAAATACAGGAACACACCTTATTATTATCGTTATGGTAA

Antitoxin


Download         Length: 91 a.a.        Molecular weight: 10388.86 Da        Isoelectric Point: 4.6702

>AT109272 WP_019843650.1 NZ_CP031505:c471394-471122 [Dickeya fangzhongdai]
MRTETKEMPINIRAKASQRELIDVAAKLLSKSRTEFILDAACREAEDVLLDQRLFLVNDEQYDAFIQVLESPVTDNPRVN
ALLNRKSPWE

Download         Length: 273 bp

>AT109272 NZ_CP031505:c471394-471122 [Dickeya fangzhongdai]
ATGCGAACAGAGACAAAAGAAATGCCGATTAATATTCGTGCTAAAGCATCACAGCGGGAGCTGATTGATGTCGCTGCTAA
ATTGCTGTCGAAATCAAGAACAGAGTTTATCCTTGATGCTGCCTGCCGTGAGGCTGAGGATGTGTTGTTGGATCAACGGC
TGTTTCTGGTCAATGATGAACAATATGATGCTTTCATTCAGGTGTTGGAATCACCTGTCACAGATAATCCGCGTGTGAAT
GCATTACTGAACAGGAAATCTCCGTGGGAATAA

Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure
AlphaFold DB A0A2K8QHE3

Antitoxin

Source ID Structure
AlphaFold DB A0A3N0G0N1

References