Detailed information of TA system TA109265

Bioinformatically predicted

Overview

TA module

• Type: II
• Classification (family/domain): relB-parE/ParE-RHH
• Location: 2839617..2840173
• Replicon: chromosome
• Accession: NZ_CP031469
• Organism: Xanthomonas oryzae pv. oryzae strain ScYc-b

Toxin (Protein)

• Gene name: parE
• Uniprot ID: -
• Locus tag: LA08_RS14070
• Protein ID: WP_027703932.1
• Coordinates: 2839617..2839907 (-)
• Length: 97 a.a.

Antitoxin (Protein)

• Gene name: relB
• Uniprot ID: A0A854CIX2
• Locus tag: LA08_RS14075
• Protein ID: WP_011408759.1
• Coordinates: 2839895..2840173 (-)
• Length: 93 a.a.

Genomic Context

Locus tag	Coordinates	Strand	Size (bp)	Protein ID	Product	Description
LA08_RS14020	2835387..2836478	+	1092	WP_041182166.1	ribonuclease D	-
LA08_RS14025	2836554..2836891	-	338	Protein_2532	ATP-dependent DNA ligase	-
LA08_RS24400	2836951..2837157	-	207	Protein_2533	hypothetical protein	-
LA08_RS14035	2837173..2837349	-	177	Protein_2534	DUF3606 domain-containing protein	-
LA08_RS14040	2837571..2837972	+	402	WP_011259345.1	H-NS histone family protein	-
LA08_RS14060	2838836..2839015	-	180	WP_015463309.1	hypothetical protein	-
LA08_RS14065	2839286..2839540	-	255	WP_198912806.1	hypothetical protein	-
LA08_RS14070	2839617..2839907	-	291	WP_027703932.1	type II toxin-antitoxin system RelE/ParE family toxin	Toxin
LA08_RS14075	2839895..2840173	-	279	WP_011408759.1	CopG family ribbon-helix-helix protein	Antitoxin
LA08_RS24655	2840254..2840457	-	204	WP_199285669.1	hypothetical protein	-
LA08_RS24660	2840369..2840713	-	345	WP_199285675.1	hypothetical protein	-
LA08_RS14085	2840658..2840858	-	201	WP_027703931.1	ribbon-helix-helix protein, CopG family	-
LA08_RS14090	2841619..2842803	-	1185	WP_011408760.1	IS256 family transposase	-
LA08_RS14100	2843384..2844349	+	966	WP_109181928.1	IS1595-like element ISXo5 family transposase	-
LA08_RS14105	2844451..2845056	+	606	Protein_2545	DNA-3-methyladenine glycosylase	-

Associated MGEs

MGE detail	Similar MGEs	Relative position	MGE Type	Cargo ARG	Virulence gene	Coordinates	Length (bp)

Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.

Domains

Predicted by InterproScan

Toxin

• Toxin-antitoxin system, RelE/ParE toxin family (4-94)

Antitoxin

• Ribbon-helix-helix protein, CopG (5-42)

Sequences

Toxin

Protein

• Length: 97 a.a.
• Molecular weight: 10915.48 Da
• Isoelectric Point: 9.5554

>T109265 WP_027703932.1 NZ_CP031469:c2839907-2839617 [Xanthomonas oryzae pv. oryzae]
MPQVIFAPAAIGDMLRLREFLRPKNPDAARRAGEAIRRGVQALGAHPRMGRLIEDLSEQYREWLIDFGDSGYVARYRFDG
DTVTILAVRHQKEAGY

Nucleotide

• Length: 291 bp

>T109265 NZ_CP031469:c2839907-2839617 [Xanthomonas oryzae pv. oryzae]
ATGCCACAAGTAATCTTTGCGCCGGCGGCGATCGGGGACATGCTACGGCTGCGTGAATTCCTGAGGCCGAAGAATCCCGA
TGCCGCGAGGCGGGCCGGCGAAGCGATTAGGCGCGGCGTCCAGGCTCTCGGTGCCCACCCTCGAATGGGGCGGCTCATAG
AAGATCTGTCTGAACAGTATCGGGAGTGGCTTATCGATTTTGGGGATAGCGGCTATGTGGCTCGGTACCGCTTCGATGGG
GATACCGTCACGATTTTGGCCGTGCGACACCAGAAGGAAGCGGGGTACTGA

Antitoxin

Protein

• Length: 93 a.a.
• Molecular weight: 10826.11 Da
• Isoelectric Point: 4.9736

>AT109265 WP_011408759.1 NZ_CP031469:c2840173-2839895 [Xanthomonas oryzae pv. oryzae]
MVTATSIKLDDELKGRVQHLAESRRRTPHWIMREAIEQYVEREEKREALNRDTLKAWDEFQATGLHVTAEEVDKWLASWG
TDDELPPPECHK

Nucleotide

• Length: 279 bp

>AT109265 NZ_CP031469:c2840173-2839895 [Xanthomonas oryzae pv. oryzae]
ATGGTTACGGCAACTTCCATCAAGCTTGATGATGAATTGAAAGGGCGGGTTCAGCACTTGGCAGAGTCGCGCCGGCGTAC
CCCGCATTGGATCATGCGCGAAGCCATTGAGCAGTACGTCGAGCGCGAGGAAAAGCGCGAGGCGCTGAACCGGGACACGC
TCAAGGCATGGGATGAATTTCAGGCGACTGGCCTGCATGTGACCGCTGAGGAAGTGGACAAGTGGCTCGCTAGCTGGGGA
ACTGACGACGAACTGCCTCCGCCAGAATGCCACAAGTAA

Structures

Antitoxin

• AlphaFold DB: A0A854CIX2