Detailed information of TA system TA109262

Bioinformatically predicted

Overview

TA module

• Type: II
• Classification (family/domain): shpA-AbkA/BrnT_toxin-BrnA
• Location: 1906816..1907419
• Replicon: chromosome
• Accession: NZ_CP031467
• Organism: Paraburkholderia caffeinilytica strain CF1

Toxin (Protein)

• Gene name: shpA
• Uniprot ID: -
• Locus tag: DSC91_RS24790
• Protein ID: WP_208645770.1
• Coordinates: 1907114..1907419 (-)
• Length: 102 a.a.

Antitoxin (Protein)

• Gene name: AbkA
• Uniprot ID: -
• Locus tag: DSC91_RS24785
• Protein ID: WP_115781285.1
• Coordinates: 1906816..1907073 (-)
• Length: 86 a.a.

Genomic Context

Locus tag	Coordinates	Strand	Size (bp)	Protein ID	Product	Description
DSC91_RS24770	1901887..1902843	+	957	WP_115781282.1	DUF979 domain-containing protein	-
DSC91_RS24775	1902943..1904547	-	1605	WP_115781283.1	tetratricopeptide repeat protein	-
DSC91_RS24780	1904924..1906729	+	1806	WP_115781284.1	tetratricopeptide repeat protein	-
DSC91_RS24785	1906816..1907073	-	258	WP_115781285.1	BrnA antitoxin family protein	Antitoxin
DSC91_RS24790	1907114..1907419	-	306	WP_208645770.1	BrnT family toxin	Toxin
DSC91_RS24795	1907592..1908743	-	1152	WP_115781287.1	TraB/GumN family protein	-
DSC91_RS24800	1908736..1909755	-	1020	WP_115781288.1	ABC transporter ATP-binding protein	-
DSC91_RS24805	1909752..1910756	-	1005	WP_115781289.1	ABC transporter ATP-binding protein	-
DSC91_RS24810	1910758..1911675	-	918	WP_115781290.1	ABC transporter permease subunit	-

Associated MGEs

MGE detail	Similar MGEs	Relative position	MGE Type	Cargo ARG	Virulence gene	Coordinates	Length (bp)

Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.

Domains

Predicted by InterproScan

Toxin

• Ribonuclease toxin, BrnT, of type II toxin-antitoxin system (14-91)

Antitoxin

• BrnA antitoxin of type II toxin-antitoxin system (27-77)

Sequences

Toxin

Protein

• Length: 102 a.a.
• Molecular weight: 12056.82 Da
• Isoelectric Point: 7.9216

>T109262 WP_208645770.1 NZ_CP031467:c1907419-1907114 [Paraburkholderia caffeinilytica]
MYRRQYRCCVRFEWDEIKNQINIHKHGIDFIDAIDVFDHPVLTAIDQREDYGEDRWIALGWIAAIVGVVVYVERSADVIR
IISARKATKHEVKRYKHSVWN

Nucleotide

• Length: 306 bp

>T109262 NZ_CP031467:c1907419-1907114 [Paraburkholderia caffeinilytica]
ATGTACAGACGTCAATACAGGTGCTGTGTGCGGTTTGAATGGGACGAAATCAAGAATCAGATCAACATCCATAAGCATGG
CATCGACTTCATAGATGCGATCGACGTGTTTGATCATCCCGTGCTGACGGCGATAGACCAGCGGGAAGATTATGGCGAGG
ATCGCTGGATCGCACTGGGCTGGATTGCTGCCATCGTAGGCGTAGTGGTGTATGTCGAACGGAGTGCGGATGTGATCCGT
ATCATTTCGGCCCGCAAGGCGACCAAACACGAAGTCAAACGCTACAAGCACAGCGTCTGGAATTGA

Antitoxin

Protein

• Length: 86 a.a.
• Molecular weight: 9794.08 Da
• Isoelectric Point: 8.5543

>AT109262 WP_115781285.1 NZ_CP031467:c1907073-1906816 [Paraburkholderia caffeinilytica]
MGKTSGTDWKRLAKTDDAQIDTSDVPELGDDFFDRAELHVPPKQAVTMRLDADVLNWFKEQGAGYQTRINKLLRAYMLAQ
QRRRP

Nucleotide

• Length: 258 bp

>AT109262 NZ_CP031467:c1907073-1906816 [Paraburkholderia caffeinilytica]
ATGGGTAAAACATCGGGAACCGACTGGAAGCGACTTGCAAAGACAGACGACGCGCAGATCGACACGAGCGACGTGCCTGA
ACTGGGCGACGACTTTTTTGACCGGGCTGAGCTGCACGTTCCGCCGAAACAGGCTGTGACGATGCGCCTGGATGCGGACG
TGCTGAACTGGTTCAAGGAACAGGGAGCGGGATATCAGACGCGCATCAACAAGTTGTTGCGCGCCTACATGCTGGCGCAG
CAGCGTCGTCGTCCTTAA