Detailed information of TA system TA109254

Bioinformatically predicted

Overview

TA module

• Type: II
• Classification (family/domain): relB-parE/ParE-RHH
• Location: 2798882..2799438
• Replicon: chromosome
• Accession: NZ_CP031464
• Organism: Xanthomonas oryzae pv. oryzae strain YC11

Toxin (Protein)

• Gene name: parE
• Uniprot ID: -
• Locus tag: BRN66_RS13865
• Protein ID: WP_027703932.1
• Coordinates: 2798882..2799172 (-)
• Length: 97 a.a.

Antitoxin (Protein)

• Gene name: relB
• Uniprot ID: A0A854CIX2
• Locus tag: BRN66_RS13870
• Protein ID: WP_011408759.1
• Coordinates: 2799160..2799438 (-)
• Length: 93 a.a.

Genomic Context

Locus tag	Coordinates	Strand	Size (bp)	Protein ID	Product	Description
BRN66_RS13815	2794652..2795743	+	1092	WP_041182166.1	ribonuclease D	-
BRN66_RS13820	2795819..2796156	-	338	Protein_2484	ATP-dependent DNA ligase	-
BRN66_RS24325	2796216..2796422	-	207	Protein_2485	hypothetical protein	-
BRN66_RS24590	2796438..2796614	-	177	Protein_2486	DUF3606 domain-containing protein	-
BRN66_RS13835	2796836..2797237	+	402	WP_011259345.1	H-NS histone family protein	-
BRN66_RS13855	2798101..2798280	-	180	WP_015463309.1	hypothetical protein	-
BRN66_RS24330	2798424..2798621	-	198	WP_004541336.1	hypothetical protein	-
BRN66_RS13865	2798882..2799172	-	291	WP_027703932.1	type II toxin-antitoxin system RelE/ParE family toxin	Toxin
BRN66_RS13870	2799160..2799438	-	279	WP_011408759.1	CopG family ribbon-helix-helix protein	Antitoxin
BRN66_RS24595	2799519..2799722	-	204	WP_199285669.1	hypothetical protein	-
BRN66_RS24600	2799634..2800020	-	387	WP_205412094.1	hypothetical protein	-
BRN66_RS13880	2799923..2800123	-	201	WP_027703931.1	ribbon-helix-helix protein, CopG family	-
BRN66_RS13885	2800884..2802068	-	1185	WP_011408760.1	IS256 family transposase	-
BRN66_RS13895	2802649..2803614	+	966	WP_109181928.1	IS1595-like element ISXo5 family transposase	-
BRN66_RS13900	2803716..2804321	+	606	Protein_2497	DNA-3-methyladenine glycosylase	-

Associated MGEs

MGE detail	Similar MGEs	Relative position	MGE Type	Cargo ARG	Virulence gene	Coordinates	Length (bp)

Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.

Domains

Predicted by InterproScan

Toxin

• Toxin-antitoxin system, RelE/ParE toxin family (4-94)

Antitoxin

• Ribbon-helix-helix protein, CopG (5-42)

Sequences

Toxin

Protein

• Length: 97 a.a.
• Molecular weight: 10915.48 Da
• Isoelectric Point: 9.5554

>T109254 WP_027703932.1 NZ_CP031464:c2799172-2798882 [Xanthomonas oryzae pv. oryzae]
MPQVIFAPAAIGDMLRLREFLRPKNPDAARRAGEAIRRGVQALGAHPRMGRLIEDLSEQYREWLIDFGDSGYVARYRFDG
DTVTILAVRHQKEAGY

Nucleotide

• Length: 291 bp

>T109254 NZ_CP031464:c2799172-2798882 [Xanthomonas oryzae pv. oryzae]
ATGCCACAAGTAATCTTTGCGCCGGCGGCGATCGGGGACATGCTACGGCTGCGTGAATTCCTGAGGCCGAAGAATCCCGA
TGCCGCGAGGCGGGCCGGCGAAGCGATTAGGCGCGGCGTCCAGGCTCTCGGTGCCCACCCTCGAATGGGGCGGCTCATAG
AAGATCTGTCTGAACAGTATCGGGAGTGGCTTATCGATTTTGGGGATAGCGGCTATGTGGCTCGGTACCGCTTCGATGGG
GATACCGTCACGATTTTGGCCGTGCGACACCAGAAGGAAGCGGGGTACTGA

Antitoxin

Protein

• Length: 93 a.a.
• Molecular weight: 10826.11 Da
• Isoelectric Point: 4.9736

>AT109254 WP_011408759.1 NZ_CP031464:c2799438-2799160 [Xanthomonas oryzae pv. oryzae]
MVTATSIKLDDELKGRVQHLAESRRRTPHWIMREAIEQYVEREEKREALNRDTLKAWDEFQATGLHVTAEEVDKWLASWG
TDDELPPPECHK

Nucleotide

• Length: 279 bp

>AT109254 NZ_CP031464:c2799438-2799160 [Xanthomonas oryzae pv. oryzae]
ATGGTTACGGCAACTTCCATCAAGCTTGATGATGAATTGAAAGGGCGGGTTCAGCACTTGGCAGAGTCGCGCCGGCGTAC
CCCGCATTGGATCATGCGCGAAGCCATTGAGCAGTACGTCGAGCGCGAGGAAAAGCGCGAGGCGCTGAACCGGGACACGC
TCAAGGCATGGGATGAATTTCAGGCGACTGGCCTGCATGTGACCGCTGAGGAAGTGGACAAGTGGCTCGCTAGCTGGGGA
ACTGACGACGAACTGCCTCCGCCAGAATGCCACAAGTAA

Structures

Antitoxin

• AlphaFold DB: A0A854CIX2