Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type II Classification (family/domain) EcnAB/-
Location 4720822..4721172 Replicon chromosome
Accession NZ_CP031463
Organism Xanthomonas oryzae pv. oryzae strain PX086

Toxin (Protein)


Gene name EcnB Uniprot ID G7TLC7
Locus tag BRN52_RS23140 Protein ID WP_011257368.1
Coordinates 4720822..4720956 (-) Length 45 a.a.

Antitoxin (Protein)


Gene name EcnA Uniprot ID G7TLC8
Locus tag BRN52_RS23145 Protein ID WP_011407410.1
Coordinates 4721020..4721172 (-) Length 51 a.a.

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
BRN52_RS23125 4717836..4718858 - 1023 WP_075240574.1 MBL fold metallo-hydrolase -
BRN52_RS23130 4718911..4720200 - 1290 WP_011257370.1 tryptophan--tRNA ligase -
BRN52_RS23135 4720369..4720578 - 210 WP_011407411.1 CsbD family protein -
BRN52_RS23140 4720822..4720956 - 135 WP_011257368.1 entericidin A/B family lipoprotein Toxin
BRN52_RS23145 4721020..4721172 - 153 WP_011407410.1 entericidin A/B family lipoprotein Antitoxin
BRN52_RS23150 4721280..4722203 - 924 WP_011407409.1 arginase -
BRN52_RS23155 4722525..4723199 + 675 WP_011257366.1 hypothetical protein -
BRN52_RS23160 4723196..4723435 + 240 WP_011257365.1 hypothetical protein -
BRN52_RS23165 4723442..4723738 + 297 WP_012446308.1 hypothetical protein -
BRN52_RS23175 4724218..4724901 + 684 WP_011257363.1 dTMP kinase -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin

Entericidin A/B

(23-42)

Antitoxin

Entericidin A/B

(23-42)


Sequences

Toxin        


Download         Length: 45 a.a.        Molecular weight: 4457.33 Da        Isoelectric Point: 10.2040

>T109252 WP_011257368.1 NZ_CP031463:c4720956-4720822 [Xanthomonas oryzae pv. oryzae]
MKRAIVLLVLSMLSVGLLSGCNTVAGAGKDVKGAGEKVEDAARK

Download         Length: 135 bp

>T109252 NZ_CP031463:c4720956-4720822 [Xanthomonas oryzae pv. oryzae]
ATGAAGCGTGCAATTGTGCTGCTCGTGCTGTCCATGTTGTCGGTCGGTCTGCTGTCGGGCTGCAACACCGTCGCAGGTGC
CGGCAAGGACGTGAAGGGCGCCGGCGAGAAGGTGGAAGACGCAGCGCGTAAGTAA

Antitoxin


Download         Length: 51 a.a.        Molecular weight: 5046.99 Da        Isoelectric Point: 8.7942

>AT109252 WP_011407410.1 NZ_CP031463:c4721172-4721020 [Xanthomonas oryzae pv. oryzae]
MKRLLTLMVLGLFSAGVMTGCNTVAGAGKDLQGAGGKVEKTAEKCSDGKC

Download         Length: 153 bp

>AT109252 NZ_CP031463:c4721172-4721020 [Xanthomonas oryzae pv. oryzae]
ATGAAGCGACTGCTGACACTGATGGTGCTGGGCCTGTTTTCGGCCGGCGTGATGACGGGCTGCAACACCGTGGCTGGCGC
TGGCAAGGACTTGCAGGGCGCGGGTGGGAAGGTCGAGAAAACGGCCGAAAAATGCAGCGATGGTAAGTGCTGA

Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure
AlphaFold DB A0A0C5UG40

Antitoxin

Source ID Structure
AlphaFold DB A0A0C5V759

References