Detailed information of TA system TA109251

Bioinformatically predicted

Overview

TA module

• Type: II
• Classification (family/domain): relB-parE/ParE-RHH
• Location: 2126774..2127330
• Replicon: chromosome
• Accession: NZ_CP031463
• Organism: Xanthomonas oryzae pv. oryzae strain PX086

Toxin (Protein)

• Gene name: parE
• Uniprot ID: -
• Locus tag: BRN52_RS10440
• Protein ID: WP_027703932.1
• Coordinates: 2127040..2127330 (+)
• Length: 97 a.a.

Antitoxin (Protein)

• Gene name: relB
• Uniprot ID: A0A854CIX2
• Locus tag: BRN52_RS10435
• Protein ID: WP_011408759.1
• Coordinates: 2126774..2127052 (+)
• Length: 93 a.a.

Genomic Context

Locus tag	Coordinates	Strand	Size (bp)	Protein ID	Product	Description
BRN52_RS10410	2121926..2123110	+	1185	WP_011408397.1	IS256 family transposase	-
BRN52_RS10415	2123514..2124482	+	969	WP_012445118.1	IS5-like element ISXo1 family transposase	-
BRN52_RS10420	2124884..2125840	+	957	WP_041182719.1	IS30-like element IS1112b family transposase	-
BRN52_RS10425	2126089..2126289	+	201	WP_027703931.1	ribbon-helix-helix protein, CopG family	-
BRN52_RS25140	2126234..2126578	+	345	WP_198912817.1	hypothetical protein	-
BRN52_RS25145	2126490..2126693	+	204	WP_198912807.1	hypothetical protein	-
BRN52_RS10435	2126774..2127052	+	279	WP_011408759.1	CopG family ribbon-helix-helix protein	Antitoxin
BRN52_RS10440	2127040..2127330	+	291	WP_027703932.1	type II toxin-antitoxin system RelE/ParE family toxin	Toxin
BRN52_RS10445	2127407..2127661	+	255	WP_198912806.1	hypothetical protein	-
BRN52_RS10450	2127932..2128111	+	180	WP_015463309.1	hypothetical protein	-
BRN52_RS10470	2128975..2129376	-	402	WP_011259345.1	H-NS histone family protein	-
BRN52_RS25150	2129598..2129774	+	177	Protein_1900	DUF3606 domain-containing protein	-
BRN52_RS24815	2129790..2129996	+	207	Protein_1901	hypothetical protein	-
BRN52_RS10485	2130056..2130372	+	317	Protein_1902	ATP-dependent DNA ligase	-
BRN52_RS10490	2130469..2131560	-	1092	WP_011408756.1	ribonuclease D	-

Associated MGEs

MGE detail	Similar MGEs	Relative position	MGE Type	Cargo ARG	Virulence gene	Coordinates	Length (bp)

Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.

Domains

Predicted by InterproScan

Toxin

• Toxin-antitoxin system, RelE/ParE toxin family (4-94)

Antitoxin

• Ribbon-helix-helix protein, CopG (5-42)

Sequences

Toxin

Protein

• Length: 97 a.a.
• Molecular weight: 10915.48 Da
• Isoelectric Point: 9.5554

>T109251 WP_027703932.1 NZ_CP031463:2127040-2127330 [Xanthomonas oryzae pv. oryzae]
MPQVIFAPAAIGDMLRLREFLRPKNPDAARRAGEAIRRGVQALGAHPRMGRLIEDLSEQYREWLIDFGDSGYVARYRFDG
DTVTILAVRHQKEAGY

Nucleotide

• Length: 291 bp

>T109251 NZ_CP031463:2127040-2127330 [Xanthomonas oryzae pv. oryzae]
ATGCCACAAGTAATCTTTGCGCCGGCGGCGATCGGGGACATGCTACGGCTGCGTGAATTCCTGAGGCCGAAGAATCCCGA
TGCCGCGAGGCGGGCCGGCGAAGCGATTAGGCGCGGCGTCCAGGCTCTCGGTGCCCACCCTCGAATGGGGCGGCTCATAG
AAGATCTGTCTGAACAGTATCGGGAGTGGCTTATCGATTTTGGGGATAGCGGCTATGTGGCTCGGTACCGCTTCGATGGG
GATACCGTCACGATTTTGGCCGTGCGACACCAGAAGGAAGCGGGGTACTGA

Antitoxin

Protein

• Length: 93 a.a.
• Molecular weight: 10826.11 Da
• Isoelectric Point: 4.9736

>AT109251 WP_011408759.1 NZ_CP031463:2126774-2127052 [Xanthomonas oryzae pv. oryzae]
MVTATSIKLDDELKGRVQHLAESRRRTPHWIMREAIEQYVEREEKREALNRDTLKAWDEFQATGLHVTAEEVDKWLASWG
TDDELPPPECHK

Nucleotide

• Length: 279 bp

>AT109251 NZ_CP031463:2126774-2127052 [Xanthomonas oryzae pv. oryzae]
ATGGTTACGGCAACTTCCATCAAGCTTGATGATGAATTGAAAGGGCGGGTTCAGCACTTGGCAGAGTCGCGCCGGCGTAC
CCCGCATTGGATCATGCGCGAAGCCATTGAGCAGTACGTCGAGCGCGAGGAAAAGCGCGAGGCGCTGAACCGGGACACGC
TCAAGGCATGGGATGAATTTCAGGCGACTGGCCTGCATGTGACCGCTGAGGAAGTGGACAAGTGGCTCGCGAGCTGGGGA
ACTGACGACGAACTGCCTCCGCCAGAATGCCACAAGTAA

Structures

Antitoxin

• AlphaFold DB: A0A854CIX2