Detailed information of TA system TA109246

Bioinformatically predicted

Overview

TA module

• Type: II
• Classification (family/domain): relB-parE/ParE-RHH
• Location: 1980138..1980694
• Replicon: chromosome
• Accession: NZ_CP031462
• Organism: Xanthomonas oryzae pv. oryzae strain PX079

Toxin (Protein)

• Gene name: parE
• Uniprot ID: -
• Locus tag: BRN51_RS09685
• Protein ID: WP_041182647.1
• Coordinates: 1980404..1980694 (+)
• Length: 97 a.a.

Antitoxin (Protein)

• Gene name: relB
• Uniprot ID: A0A854CIX2
• Locus tag: BRN51_RS09680
• Protein ID: WP_011408759.1
• Coordinates: 1980138..1980416 (+)
• Length: 93 a.a.

Genomic Context

Locus tag	Coordinates	Strand	Size (bp)	Protein ID	Product	Description
BRN51_RS09650	1975255..1975860	-	606	Protein_1771	DNA-3-methyladenine glycosylase	-
BRN51_RS09655	1975962..1976927	-	966	WP_109181928.1	IS1595-like element ISXo5 family transposase	-
BRN51_RS09665	1977508..1978692	+	1185	WP_011408397.1	IS256 family transposase	-
BRN51_RS09670	1979453..1979653	+	201	WP_027703931.1	ribbon-helix-helix protein, CopG family	-
BRN51_RS25330	1979598..1979942	+	345	WP_198912817.1	hypothetical protein	-
BRN51_RS25335	1979854..1980057	+	204	WP_198912807.1	hypothetical protein	-
BRN51_RS09680	1980138..1980416	+	279	WP_011408759.1	CopG family ribbon-helix-helix protein	Antitoxin
BRN51_RS09685	1980404..1980694	+	291	WP_041182647.1	type II toxin-antitoxin system RelE/ParE family toxin	Toxin
BRN51_RS09690	1980771..1981025	+	255	WP_198912806.1	hypothetical protein	-
BRN51_RS09695	1981296..1981475	+	180	WP_015463309.1	hypothetical protein	-
BRN51_RS09710	1981977..1982775	+	799	WP_094187731.1	IS5 family transposase	-
BRN51_RS09720	1983191..1983592	-	402	WP_011259345.1	H-NS histone family protein	-
BRN51_RS25340	1983814..1983990	+	177	Protein_1783	DUF3606 domain-containing protein	-
BRN51_RS24995	1984006..1984212	+	207	Protein_1784	hypothetical protein	-
BRN51_RS09735	1984272..1984588	+	317	Protein_1785	ATP-dependent DNA ligase	-

Associated MGEs

MGE detail	Similar MGEs	Relative position	MGE Type	Cargo ARG	Virulence gene	Coordinates	Length (bp)
	-	inside	IScluster/Tn	-	-	1975962..1982775	6813

Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.

Domains

Predicted by InterproScan

Toxin

• Toxin-antitoxin system, RelE/ParE toxin family (4-94)

Antitoxin

• Ribbon-helix-helix protein, CopG (5-42)

Sequences

Toxin

Protein

• Length: 97 a.a.
• Molecular weight: 10929.51 Da
• Isoelectric Point: 9.5554

>T109246 WP_041182647.1 NZ_CP031462:1980404-1980694 [Xanthomonas oryzae pv. oryzae]
MPQVIFAPAAIGDMLRLREFLRPKNPDAARRAGEAIRRGVQALGAHPRMGRLIEDLSEQYREWLIDFGDSGYVARYRFDG
DTVTILALRHQKEAGY

Nucleotide

• Length: 291 bp

>T109246 NZ_CP031462:1980404-1980694 [Xanthomonas oryzae pv. oryzae]
ATGCCACAAGTAATCTTTGCGCCGGCGGCGATCGGGGACATGCTACGGCTGCGTGAATTCCTGAGGCCGAAGAATCCCGA
TGCCGCGAGGCGGGCCGGCGAAGCGATTAGGCGCGGCGTCCAGGCTCTCGGTGCCCACCCTCGAATGGGGCGGCTCATAG
AAGATCTGTCTGAACAGTATCGGGAGTGGCTTATCGATTTTGGGGATAGCGGCTATGTGGCTCGGTACCGCTTCGATGGG
GATACCGTCACGATTTTGGCCCTGCGACACCAGAAGGAAGCGGGGTACTGA

Antitoxin

Protein

• Length: 93 a.a.
• Molecular weight: 10826.11 Da
• Isoelectric Point: 4.9736

>AT109246 WP_011408759.1 NZ_CP031462:1980138-1980416 [Xanthomonas oryzae pv. oryzae]
MVTATSIKLDDELKGRVQHLAESRRRTPHWIMREAIEQYVEREEKREALNRDTLKAWDEFQATGLHVTAEEVDKWLASWG
TDDELPPPECHK

Nucleotide

• Length: 279 bp

>AT109246 NZ_CP031462:1980138-1980416 [Xanthomonas oryzae pv. oryzae]
ATGGTTACGGCAACTTCCATCAAGCTTGATGATGAATTGAAAGGGCGGGTTCAGCACTTGGCAGAGTCGCGCCGGCGTAC
CCCGCATTGGATCATGCGCGAAGCCATTGAGCAGTACGTCGAGCGCGAGGAAAAGCGCGAGGCGCTGAACCGGGACACGC
TCAAGGCATGGGATGAATTTCAGGCGACTGGCCTGCATGTGACCGCTGAGGAAGTGGACAAGTGGCTCGCGAGCTGGGGA
ACTGACGACGAACTGCCTCCGCCAGAATGCCACAAGTAA

Structures

Antitoxin

• AlphaFold DB: A0A854CIX2