Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type II Classification (family/domain) EcnAB/-
Location 426012..426362 Replicon chromosome
Accession NZ_CP031461
Organism Xanthomonas oryzae pv. oryzae strain OS198

Toxin (Protein)


Gene name EcnB Uniprot ID G7TLC7
Locus tag BRN32_RS02180 Protein ID WP_011257368.1
Coordinates 426228..426362 (+) Length 45 a.a.

Antitoxin (Protein)


Gene name EcnA Uniprot ID G7TLC8
Locus tag BRN32_RS02175 Protein ID WP_011407410.1
Coordinates 426012..426164 (+) Length 51 a.a.

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
BRN32_RS02145 (BRN32_02145) 422283..422966 - 684 WP_011257363.1 dTMP kinase -
BRN32_RS24925 423446..423988 - 543 Protein_386 GTPase -
BRN32_RS02165 (BRN32_02165) 423985..424449 - 465 Protein_387 hypothetical protein -
BRN32_RS24930 424441..424659 - 219 Protein_388 hypothetical protein -
BRN32_RS02170 (BRN32_02170) 424981..425904 + 924 WP_011407409.1 arginase -
BRN32_RS02175 (BRN32_02175) 426012..426164 + 153 WP_011407410.1 entericidin A/B family lipoprotein Antitoxin
BRN32_RS02180 (BRN32_02180) 426228..426362 + 135 WP_011257368.1 entericidin A/B family lipoprotein Toxin
BRN32_RS02185 (BRN32_02185) 426606..426815 + 210 WP_011407411.1 CsbD family protein -
BRN32_RS02190 (BRN32_02190) 426984..428273 + 1290 WP_069959696.1 tryptophan--tRNA ligase -
BRN32_RS02195 (BRN32_02195) 428404..429348 + 945 WP_027704118.1 MBL fold metallo-hydrolase -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin

Entericidin A/B

(23-42)

Antitoxin

Entericidin A/B

(23-42)


Sequences

Toxin        


Download         Length: 45 a.a.        Molecular weight: 4457.33 Da        Isoelectric Point: 10.2040

>T109241 WP_011257368.1 NZ_CP031461:426228-426362 [Xanthomonas oryzae pv. oryzae]
MKRAIVLLVLSMLSVGLLSGCNTVAGAGKDVKGAGEKVEDAARK

Download         Length: 135 bp

>T109241 NZ_CP031461:426228-426362 [Xanthomonas oryzae pv. oryzae]
ATGAAGCGTGCAATTGTGCTGCTCGTGCTGTCCATGTTGTCGGTCGGTCTGCTGTCGGGCTGCAACACCGTCGCAGGTGC
CGGCAAGGACGTGAAGGGCGCCGGCGAGAAGGTGGAAGACGCAGCGCGTAAGTAA

Antitoxin


Download         Length: 51 a.a.        Molecular weight: 5046.99 Da        Isoelectric Point: 8.7942

>AT109241 WP_011407410.1 NZ_CP031461:426012-426164 [Xanthomonas oryzae pv. oryzae]
MKRLLTLMVLGLFSAGVMTGCNTVAGAGKDLQGAGGKVEKTAEKCSDGKC

Download         Length: 153 bp

>AT109241 NZ_CP031461:426012-426164 [Xanthomonas oryzae pv. oryzae]
ATGAAGCGACTGCTGACACTGATGGTGCTGGGCCTGTTTTCGGCCGGCGTGATGACGGGCTGCAACACCGTGGCTGGCGC
TGGCAAGGACTTGCAGGGCGCGGGTGGGAAGGTCGAGAAAACGGCCGAAAAATGCAGCGATGGTAAGTGCTGA

Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure
AlphaFold DB A0A0C5UG40

Antitoxin

Source ID Structure
AlphaFold DB A0A0C5V759

References