109237

Detailed information of TA system    

insolicoBioinformatically predicted

Overview


TA module


Type II Classification (family/domain) EcnAB/-
Location 426868..427218 Replicon chromosome
Accession NZ_CP031460
Organism Xanthomonas oryzae pv. oryzae strain JP01

Toxin (Protein)


Gene name EcnB Uniprot ID G7TLC7
Locus tag BRM88_RS02140 Protein ID WP_011257368.1
Coordinates 427084..427218 (+) Length 45 a.a.

Antitoxin (Protein)


Gene name EcnA Uniprot ID G7TLC8
Locus tag BRM88_RS02135 Protein ID WP_011407410.1
Coordinates 426868..427020 (+) Length 51 a.a.

Genomic Context


Locus tag Coordinates Strand Size (bp) Protein ID Product Description
BRM88_RS02105 423139..423822 - 684 WP_011257363.1 dTMP kinase -
BRM88_RS02115 424302..424598 - 297 WP_011257364.1 hypothetical protein -
BRM88_RS02120 424605..424844 - 240 WP_011257365.1 hypothetical protein -
BRM88_RS02125 424841..425515 - 675 WP_011257366.1 hypothetical protein -
BRM88_RS02130 425837..426760 + 924 WP_011407409.1 arginase -
BRM88_RS02135 426868..427020 + 153 WP_011407410.1 entericidin A/B family lipoprotein Antitoxin
BRM88_RS02140 427084..427218 + 135 WP_011257368.1 entericidin A/B family lipoprotein Toxin
BRM88_RS02145 427462..427671 + 210 WP_011407411.1 CsbD family protein -
BRM88_RS02150 427840..429129 + 1290 WP_011257370.1 tryptophan--tRNA ligase -
BRM88_RS02155 429182..430204 + 1023 WP_011257371.1 MBL fold metallo-hydrolase -

Associated MGEs


MGE
detail
Similar
MGEs
Relative
position
MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains


Predicted by InterproScan

Toxin

(23-42)

Antitoxin

(23-42)


Sequences


Toxin        


Download         Length: 45 a.a.        Molecular weight: 4457.33 Da        Isoelectric Point: 10.2040

>T109237 WP_011257368.1 NZ_CP031460:427084-427218 [Xanthomonas oryzae pv. oryzae]
MKRAIVLLVLSMLSVGLLSGCNTVAGAGKDVKGAGEKVEDAARK

Download         Length: 135 bp

>T109237 NZ_CP031460:427084-427218 [Xanthomonas oryzae pv. oryzae]
ATGAAGCGTGCAATTGTGCTGCTCGTGCTGTCCATGTTGTCGGTCGGTCTGCTGTCGGGCTGCAACACCGTCGCAGGTGC
CGGCAAGGACGTGAAGGGCGCCGGCGAGAAGGTGGAAGACGCAGCGCGTAAGTAA

Antitoxin


Download         Length: 51 a.a.        Molecular weight: 5046.99 Da        Isoelectric Point: 8.7942

>AT109237 WP_011407410.1 NZ_CP031460:426868-427020 [Xanthomonas oryzae pv. oryzae]
MKRLLTLMVLGLFSAGVMTGCNTVAGAGKDLQGAGGKVEKTAEKCSDGKC

Download         Length: 153 bp

>AT109237 NZ_CP031460:426868-427020 [Xanthomonas oryzae pv. oryzae]
ATGAAGCGACTGCTGACACTGATGGTGCTGGGCCTGTTTTCGGCCGGCGTGATGACGGGCTGCAACACCGTGGCTGGCGC
TGGCAAGGACTTGCAGGGCGCGGGTGGGAAGGTCGAGAAAACGGCCGAAAAATGCAGCGATGGTAAGTGCTGA

Similar Proteins


Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures


Toxin

Source ID Structure
AlphaFold DB A0A0C5UG40


Antitoxin

Source ID Structure
AlphaFold DB A0A0C5V759

References