Detailed information of TA system TA109231

Bioinformatically predicted

Overview

TA module

• Type: II
• Classification (family/domain): relB-parE/ParE-RHH
• Location: 2039771..2040327
• Replicon: chromosome
• Accession: NZ_CP031458
• Organism: Xanthomonas oryzae pv. oryzae strain JL28

Toxin (Protein)

• Gene name: parE
• Uniprot ID: -
• Locus tag: BRM78_RS10125
• Protein ID: WP_027703932.1
• Coordinates: 2040037..2040327 (+)
• Length: 97 a.a.

Antitoxin (Protein)

• Gene name: relB
• Uniprot ID: A0A854CIX2
• Locus tag: BRM78_RS10120
• Protein ID: WP_011408759.1
• Coordinates: 2039771..2040049 (+)
• Length: 93 a.a.

Genomic Context

Locus tag	Coordinates	Strand	Size (bp)	Protein ID	Product	Description
BRM78_RS10090	2034888..2035493	-	606	Protein_1820	DNA-3-methyladenine glycosylase	-
BRM78_RS10095	2035595..2036560	-	966	WP_109181928.1	IS1595-like element ISXo5 family transposase	-
BRM78_RS10105	2037141..2038325	+	1185	WP_011408760.1	IS256 family transposase	-
BRM78_RS10110	2039086..2039286	+	201	WP_027703931.1	ribbon-helix-helix protein, CopG family	-
BRM78_RS23715	2039231..2039575	+	345	WP_199285675.1	hypothetical protein	-
BRM78_RS23720	2039487..2039690	+	204	WP_199285669.1	hypothetical protein	-
BRM78_RS10120	2039771..2040049	+	279	WP_011408759.1	CopG family ribbon-helix-helix protein	Antitoxin
BRM78_RS10125	2040037..2040327	+	291	WP_027703932.1	type II toxin-antitoxin system RelE/ParE family toxin	Toxin
BRM78_RS23385	2040588..2040785	+	198	WP_004541336.1	hypothetical protein	-
BRM78_RS10135	2040929..2041108	+	180	WP_015463309.1	hypothetical protein	-
BRM78_RS10155	2041972..2042373	-	402	WP_011259345.1	H-NS histone family protein	-
BRM78_RS23725	2042595..2042771	+	177	Protein_1831	DUF3606 domain-containing protein	-
BRM78_RS23390	2042787..2042993	+	207	Protein_1832	hypothetical protein	-
BRM78_RS10170	2043053..2043390	+	338	Protein_1833	ATP-dependent DNA ligase	-
BRM78_RS10175	2043466..2044557	-	1092	WP_041182166.1	ribonuclease D	-

Associated MGEs

MGE detail	Similar MGEs	Relative position	MGE Type	Cargo ARG	Virulence gene	Coordinates	Length (bp)

Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.

Domains

Predicted by InterproScan

Toxin

• Toxin-antitoxin system, RelE/ParE toxin family (4-94)

Antitoxin

• Ribbon-helix-helix protein, CopG (5-42)

Sequences

Toxin

Protein

• Length: 97 a.a.
• Molecular weight: 10915.48 Da
• Isoelectric Point: 9.5554

>T109231 WP_027703932.1 NZ_CP031458:2040037-2040327 [Xanthomonas oryzae pv. oryzae]
MPQVIFAPAAIGDMLRLREFLRPKNPDAARRAGEAIRRGVQALGAHPRMGRLIEDLSEQYREWLIDFGDSGYVARYRFDG
DTVTILAVRHQKEAGY

Nucleotide

• Length: 291 bp

>T109231 NZ_CP031458:2040037-2040327 [Xanthomonas oryzae pv. oryzae]
ATGCCACAAGTAATCTTTGCGCCGGCGGCGATCGGGGACATGCTACGGCTGCGTGAATTCCTGAGGCCGAAGAATCCCGA
TGCCGCGAGGCGGGCCGGCGAAGCGATTAGGCGCGGCGTCCAGGCTCTCGGTGCCCACCCTCGAATGGGGCGGCTCATAG
AAGATCTGTCTGAACAGTATCGGGAGTGGCTTATCGATTTTGGGGATAGCGGCTATGTGGCTCGGTACCGCTTCGATGGG
GATACCGTCACGATTTTGGCCGTGCGACACCAGAAGGAAGCGGGGTACTGA

Antitoxin

Protein

• Length: 93 a.a.
• Molecular weight: 10826.11 Da
• Isoelectric Point: 4.9736

>AT109231 WP_011408759.1 NZ_CP031458:2039771-2040049 [Xanthomonas oryzae pv. oryzae]
MVTATSIKLDDELKGRVQHLAESRRRTPHWIMREAIEQYVEREEKREALNRDTLKAWDEFQATGLHVTAEEVDKWLASWG
TDDELPPPECHK

Nucleotide

• Length: 279 bp

>AT109231 NZ_CP031458:2039771-2040049 [Xanthomonas oryzae pv. oryzae]
ATGGTTACGGCAACTTCCATCAAGCTTGATGATGAATTGAAAGGGCGGGTTCAGCACTTGGCAGAGTCGCGCCGGCGTAC
CCCGCATTGGATCATGCGCGAAGCCATTGAGCAGTACGTCGAGCGCGAGGAAAAGCGCGAGGCGCTGAACCGGGACACGC
TCAAGGCATGGGATGAATTTCAGGCGACTGGCCTGCATGTGACCGCTGAGGAAGTGGACAAGTGGCTCGCTAGCTGGGGA
ACTGACGACGAACTGCCTCCGCCAGAATGCCACAAGTAA

Structures

Antitoxin

• AlphaFold DB: A0A854CIX2