109225

Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type II Classification (family/domain) EcnAB/-
Location 426196..426546 Replicon chromosome
Accession NZ_CP031457
Organism Xanthomonas oryzae pv. oryzae strain JL25

Toxin (Protein)


Gene name EcnB Uniprot ID G7TLC7
Locus tag BRM77_RS02130 Protein ID WP_011257368.1
Coordinates 426412..426546 (+) Length 45 a.a.

Antitoxin (Protein)


Gene name EcnA Uniprot ID G7TLC8
Locus tag BRM77_RS02125 Protein ID WP_011407410.1
Coordinates 426196..426348 (+) Length 51 a.a.

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
BRM77_RS02095 422467..423150 - 684 WP_011257363.1 dTMP kinase -
BRM77_RS02105 423630..423926 - 297 WP_011257364.1 hypothetical protein -
BRM77_RS02110 423933..424172 - 240 WP_011257365.1 hypothetical protein -
BRM77_RS02115 424169..424843 - 675 WP_011257366.1 hypothetical protein -
BRM77_RS02120 425165..426088 + 924 WP_011407409.1 arginase -
BRM77_RS02125 426196..426348 + 153 WP_011407410.1 entericidin A/B family lipoprotein Antitoxin
BRM77_RS02130 426412..426546 + 135 WP_011257368.1 entericidin A/B family lipoprotein Toxin
BRM77_RS02135 426790..426999 + 210 WP_011407411.1 CsbD family protein -
BRM77_RS02140 427168..428457 + 1290 WP_011257370.1 tryptophan--tRNA ligase -
BRM77_RS02145 428510..429532 + 1023 WP_011257371.1 MBL fold metallo-hydrolase -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin

Entericidin A/B

(23-42)

Antitoxin

Entericidin A/B

(23-42)


Sequences

Toxin        


Download         Length: 45 a.a.        Molecular weight: 4457.33 Da        Isoelectric Point: 10.2040

>T109225 WP_011257368.1 NZ_CP031457:426412-426546 [Xanthomonas oryzae pv. oryzae]
MKRAIVLLVLSMLSVGLLSGCNTVAGAGKDVKGAGEKVEDAARK

Download         Length: 135 bp

>T109225 NZ_CP031457:426412-426546 [Xanthomonas oryzae pv. oryzae]
ATGAAGCGTGCAATTGTGCTGCTCGTGCTGTCCATGTTGTCGGTCGGTCTGCTGTCGGGCTGCAACACCGTCGCAGGTGC
CGGCAAGGACGTGAAGGGCGCCGGCGAGAAGGTGGAAGACGCAGCGCGTAAGTAA

Antitoxin


Download         Length: 51 a.a.        Molecular weight: 5046.99 Da        Isoelectric Point: 8.7942

>AT109225 WP_011407410.1 NZ_CP031457:426196-426348 [Xanthomonas oryzae pv. oryzae]
MKRLLTLMVLGLFSAGVMTGCNTVAGAGKDLQGAGGKVEKTAEKCSDGKC

Download         Length: 153 bp

>AT109225 NZ_CP031457:426196-426348 [Xanthomonas oryzae pv. oryzae]
ATGAAGCGACTGCTGACACTGATGGTGCTGGGCCTGTTTTCGGCCGGCGTGATGACGGGCTGCAACACCGTGGCTGGCGC
TGGCAAGGACTTGCAGGGCGCGGGTGGGAAGGTCGAGAAAACGGCCGAAAAATGCAGCGATGGTAAGTGCTGA

Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure
AlphaFold DB A0A0C5UG40

Antitoxin

Source ID Structure
AlphaFold DB A0A0C5V759

References